The mutation semidominant lethal spotting arose spontaneously in 1997 in the C57BL/6J colony of the Mouse Mutant Resource at The Jackson Laboratory. It has been maintained on this background by sibling inbreeding heterozygotes and wild type siblings.
|Allele Name||semidominant lethal spotting|
|Gene Symbol and Name||Sls, semidominant lethal spotting|
|Strain of Origin||C57BL/6J|
|Molecular Note||This spontaneous mutation arose at The Jackson Laboratory. This mutation causes a phenotype similar to that of the original lethal spotting mutation, and maps to the same region of Chr 2; however, as this allele is dominant, no complementation test was performed.|
When using the C57BL/6J-Sls/GrsrJ mouse strain in a publication, please cite the originating article(s) and include JAX stock #005135 in your Materials and Methods section.