C3H/HeJ-Mfs/J

Stock number: 004806
Research areas: Dermatology Research

Detailed description

Both male and female mice homozygous or heterozygous for the Mfs mutation have a striped pattern in their coats that is visible by 3 weeks of age.

Development

The Mfs mutation arose spontaneously in a mutant coisogenic subline of C3H/HeJ at The Jackson Laboratory in 1997 and has been maintained by sibling inbreeding heterozygotes and wildtype siblings, with the pre-existing dominant mutation selected against yielding this strain with Mfs on an otherwise pure C3H/HeJ background.

Allele

Symbol: Mfs
Name: mutant fur is striped
MGI accession ID: MGI:2673985
Generation method: Spontaneous
Marker symbol: Mfs
Marker name: mutant fur striped
Chromosome: 13
Strain of origin: C3H/HeJ