Both male and female mice homozygous or heterozygous for the Mfs mutation have a striped pattern in their coats that is visible by 3 weeks of age.
Genetic Background | Generation |
---|---|
|
Allele Type | Gene Symbol | Gene Name |
---|---|---|
Spontaneous | Mfs | mutant fur striped |
This strain may carry a chromosomal inversion on Chromosome 6 (see C3H/HeJ, Stock No. 000659).
Both male and female mice homozygous or heterozygous for the Mfs mutation have a striped pattern in their coats that is visible by 3 weeks of age.
The Mfs mutation arose spontaneously in a mutant coisogenic subline of C3H/HeJ at The Jackson Laboratory in 1997 and has been maintained by sibling inbreeding heterozygotes and wildtype siblings, with the pre-existing dominant mutation selected against yielding this strain with Mfs on an otherwise pure C3H/HeJ background.
When using the C3H/HeJ-Mfs/J mouse strain in a publication, please cite the originating article(s) and include JAX stock #004806 in your Materials and Methods section.
Facility Barrier Level Descriptions
Service/Product | Description | Price |
---|---|---|
Heterozygous or Wild type for Mfs |
Frozen Mouse Embryo | C3H/HeJ-Mfs/J | $2595.00 |
Frozen Mouse Embryo | C3H/HeJ-Mfs/J | $2595.00 |
Frozen Mouse Embryo | C3H/HeJ-Mfs/J | $3373.50 |
Frozen Mouse Embryo | C3H/HeJ-Mfs/J | $3373.50 |
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.
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