Mice homozygous for this recessive mutation are recognizable by 2.5 - 3 weeks of age by their smaller body size, gaunt torso, frailty, and constant quivering which is most obvious from the nose to the abdominal-thoracic area. Mutants also show poor ability to hold onto an edge with either their fore- or hindlimbs. Adult mutants may chatter excessively. Some homozygous mutants die before weaning; others survive through adulthood but they are unreliable breeders. twithas been mapped between the flanking markers D14Mit44 and D14Mit175 in the B band of Chr 14 at 22.9 Mb and 27.9 Mb, respectively.

These mice carry a spontaneous, recessive mutation characterized by smaller body size, gaunt torso, frailty, and constant quivering.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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