Genetic Background | Generation |
---|---|
|
Allele Type | Gene Symbol | Gene Name |
---|---|---|
Spontaneous | Ap3b1 | adaptor-related protein complex 3, beta 1 subunit |
Allele Type | Gene Symbol | Gene Name |
---|---|---|
Not Applicable (Not Applicable) | H2-T18 | histocompatibility 2, T region locus 18 |
Allele Type | Gene Symbol | Gene Name |
---|---|---|
Not Applicable | H2 | histocompatibility-2, MHC |
Marker Symbol | Marker Name | |
---|---|---|
H2 | histocompatibility-2, MHC | |
H2-T18 | histocompatibility 2, T region locus 18 |
Allele Name | pearl 11 Jackson |
---|---|
Allele Type | Spontaneous |
Allele Synonym(s) | |
Gene Symbol and Name | Ap3b1, adaptor-related protein complex 3, beta 1 subunit |
Gene Synonym(s) | |
Strain of Origin | B10.RIII-H2r/(71NS)SnJ |
Chromosome | 13 |
General Note | This remutation arose spontaneously on the B10.RIII-H2r(71NS)/Sn strain. Homozygotes have lighter eye color at birth and a diluted gray coat color not different from the original pearl allele. Both homozygous males and females are fertile, and females are good mothers. Mice from this strain were not tested for differences in lysosomal enzymes or for platelet storage pool deficiency, both of which are common in other Ap3b1 mutations. DNA was saved from this remutation (J:51014, J:51188) |
Molecular Note | The molecular lesion in pe11J has not yet been resolved. |
Allele Name | b variant |
---|---|
Allele Type | Not Applicable (Not Applicable) |
Allele Synonym(s) | TL-; Tlab |
Gene Symbol and Name | H2-T18, histocompatibility 2, T region locus 18 |
Gene Synonym(s) | |
Strain of Origin | Not Applicable |
Chromosome | 17 |
Molecular Note | The allele H2-T18b determines absence of the antigen (TL-) and occurs in strains C57BL/6, AKR, C3H/An, and many others. |
Marker Synonym(s) | |
---|---|
Chromosome(s) | 17 |
Marker Synonym(s) | |
---|---|
Chromosome(s) | 17 |
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