This strain is currently available as cryopreserved stocks.
J. C. Schofield, University of Otago
In 1930 W.H. Hall brought random bred mice from the Imperial Cancer Research Fund Laboratories at Mill Hill, London to the Univiersity of Otago Medical School, New Zealand. In 1948 several pairs of mice from this colony, which had no systematic relationship, were sent to Marianne Bielschowsky and C. M. Goodall at the Hugh Adam Department of Cancer Research and these researchers generated several inbred strains from these mice. A pair of agouti mice became the founders for inbreeding and at F3 some offspring were found to have black coats. One pair of black siblings was used as the foundation for the NZB/Bl inbred strain, which reached generation F82 in 1970. Hemolytic anemia developed as a strain characteristic, identified as early as F11 (Bielschowsky and Goodall, 1970). In the spring of 1999, when that strain was at inbreeding generation F105, mice were sent from Dr. J. C. Schofield of The University of Otago, Dunedin, New Zealand, to The Jackson Laboratory. This strain continued to be maintained by sibling intercross and in 2003 embryos were cryopreserved from parents at generation F109.
Currently there are no related genes or alleles for this strain.
When using the NZB/OsuJ mouse strain in a publication, please include JAX stock #003559 in your Materials and Methods section.
Facility Barrier Level Descriptions
Service/Product | Description | Price |
---|---|---|
Inbred, 1 pair minimum will be supplied |
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.
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