This strain has been discontinued. The Jackson Laboratory Repository has been provided with sufficient evidence that the mutation is not targeted to the Bcl3 gene in the manner described in the primary publication (Schwarz et al. 1997 Genes Dev 11:187). While the exact targeting event is in question, published data demonstrate the lack of functional BCL3 protein in this mutant stock (Hunter and Kandarian 2004 J Clin Invest 114:1504). Should new data describing the targeting event in Stock No. 003127 become available, we will update our strain data sheet and reconsider the availability of this stock. Please search the <a href="http://www.jax.org/jaxmice/query">JAX&reg; Mice Database</a> for an alternative strain.

Please contact <a target="_blank" href="https://www.jax.org/jax-mice-and-services/customer-support/technical-support/contact-technical-support-form">Technical Support</a> for more information.