ZALENDE/EiJ

Stock number: 001392
Research areas: Dermatology Research, Research Tools

Description

This wild-derived inbred strain is homozygous for 7 Robertsonian translocations: Rb(1.3)1Bnr, Rb(4.6)2Bnr, Rb(5.15)3Bnr, Rb(11.13)4Bnr, Rb(8.12)5Bnr, Rb(9.14)6Bnr, and Rb(16.17)7Bnr (abbreviated Rb1Bnr - Rb7Bnr, respectively).

Detailed description

This wild-derived inbred strain is homozygous for 7 Robertsonian translocations: Rb(1.3)1Bnr, Rb(4.6)2Bnr, Rb(5.15)3Bnr, Rb(11.13)4Bnr, Rb(8.12)5Bnr, Rb(9.14)6Bnr, and Rb(16.17)7Bnr (abbreviated Rb1Bnr - Rb7Bnr, respectively)(LL Washburn, pers. comm.).

Development

The ZALENDE/EiJ inbred strain is descended from mice trapped by RD Sage in the Poschiavinus Valley, Zalende, Switzerland; mice from Sage's colony were transferred to M Potter, at NIH, in 1981. The colony at The Jackson Laboratory was initiated from a single pair of mice obtained from Potter by EM Eicher in 1982 (LL Washburn, personal communication).

Allele

Symbol: Cox7a2l^l
Name: long
MGI accession ID: MGI:6276121
Generation method: Not Applicable
Attributes: Not Specified
Marker symbol: Cox7a2l
Marker name: cytochrome c oxidase subunit 7A2 like
Chromosome: 17
Strain of origin: multiple strains
Molecular note: This allele encodes the long isoform with 113 amino acids. It is found in 129S2/SvPasCrl, CBA/CaOlaHsd, Hsd:ICR, and NZB/OlaHsd.
General note: Querying the sequences of the Sanger Mouse Genomes Project reveals that the short allele with its 6 bp deletion exists in C57BL/6J, C57BL/10J, C57BL/6NJ, C58/J, BALB/cJ, C3H/HeH, 129S5/SvEvBrd, NZW/LacZ, and SEA/GnJ, but the long allele lacking the deletion exists in 129S1/SvImJ, A/J, AKR/J, BTBR T⁺ Itpr3^tf/J, BUB/BnJ, C3H/HeJ, C57BR/cdJ, C57L/J, CAST/EiJ, CBA/J, DBA/1J, DBA/2J, FVB/NJ, I/LnJ, KK/HiJ, LEWES/EiJ, LP/J, MOLF/EiJ, NOD/ShiLtJ, NZB/BlNJ, NZO/HlLtJ, PWK/PhJ, RF/J, SPRET/EiJ, ST/bJ, WSB/EiJ, ZALENDE/EiJ.

Allele

MGI accession ID: MGI:104098
Marker symbol: Rb(11.13)4Bnr
Marker name: Robertsonian translocation, Chr 11 and 13, Universitat Bonn/Rhein 4
Chromosome: 11

Allele

MGI accession ID: MGI:103783
Marker symbol: Rb(4.6)2Bnr
Marker name: Robertsonian translocation, Chr 4 and 6, Universitat Bonn/Rhein 2
Chromosome: 4

Allele

MGI accession ID: MGI:103615
Marker symbol: Rb(1.3)1Bnr
Marker name: Robertsonian translocation, Chr 1 and 3, Universitat Bonn/Rhein 1
Chromosome: 1

Allele

MGI accession ID: MGI:104028
Marker symbol: Rb(9.14)6Bnr
Marker name: Robertsonian translocation, Chr 9 and 14, Universitat Bonn/Rhein 6
Chromosome: 9

Allele

MGI accession ID: MGI:103848
Marker symbol: Rb(5.15)3Bnr
Marker name: Robertsonian translocation, Chr 5 and 15, Universitat Bonn/Rhein 3
Chromosome: 5

Allele

MGI accession ID: MGI:103992
Marker symbol: Rb(8.12)5Bnr
Marker name: Robertsonian translocation, Chr 8 and 12, Universitat Bonn/Rhein 5
Chromosome: 8

Allele

MGI accession ID: MGI:104200
Marker symbol: Rb(16.17)7Bnr
Marker name: Robertsonian translocation, Chr 16 and 17, Universitat Bonn/Rhein 7
Chromosome: 16