JAX
Mouse Strain Datasheet - 001145
WSB/EiJ
Watkins Star Line B (WSB) was derived from wild mice trapped in Eastern Shore, Maryland. Wild-derived mice are genetically distinct from common laboratory mice for a number of complex phenotypic characteristics and are valuable tools for genetic mapping, evolution and systematics research.
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Research Areas By Genotype
This mouse can be used to support research in many areas including:
- Dermatology Research
- Color and White Spotting Defects
- Research Tools
- Genetics Research
- Evolution and Systematics Research
- Gene Mapping
- Genetics Research
Phenotype Information
References
- Petkov PM; Cassell MA; Sargent EE; Donnelly CJ; Robinson P; Crew V; Asquith S; Haar RV; Wiles MV. 2004. Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse. Genomics 83(5):902-11. PubMed: 15081119MGI: J:89298
- Timmermans S; Van Montagu M; Libert C. 2017. Complete overview of protein-inactivating sequence variations in 36 sequenced mouse inbred strains. Proc Natl Acad Sci U S A 114(34):9158-9163. PubMed: 28784771MGI: J:244295
Additional References
- Aylor DL; Valdar W; Foulds-Mathes W; Buus RJ; Verdugo RA; Baric RS; Ferris MT; Frelinger JA; Heise M; Frieman MB; Gralinski LE; Bell TA; Didion JD; Hua K; Nehrenberg DL; Powell CL; Steigerwalt J; Xie Y; Kelada SN; Collins FS; Yang IV; Schwartz DA; Branstetter LA; Chesler EJ; Miller DR; Spence J; Liu EY; McMillan L; Sarkar A; Wang J; Wang W; Zhang Q; Broman KW; Korstanje R; Durrant C; Mott R; Iraqi FA; Pomp D; Threadgill D; de Villena FP; Churchill GA. 2011. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res 21(8):1213-22. PubMed: 21406540MGI: J:169740
- Bell TA; de la Casa-Esperon E; Doherty HE; Ideraabdullah F; Kim K; Wang Y; Lange LA; Wilhemsen K; Lange EM; Sapienza C; de Villena FP. 2006. The Paternal Gene of the DDK Syndrome Maps to the Schlafen Gene Cluster on Mouse Chromosome 11. Genetics 172(1):411-23. PubMed: 16172501MGI: J:105162
- Didion JP; Morgan AP; Clayshulte AM; Mcmullan RC; Yadgary L; Petkov PM; Bell TA; Gatti DM; Crowley JJ; Hua K; Aylor DL; Bai L; Calaway M; Chesler EJ; French JE; Geiger TR; Gooch TJ; Garland T Jr; Harrill AH; Hunter K; McMillan L; Holt M; Miller DR; O'Brien DA; Paigen K; Pan W; Rowe LB; Shaw GD; Simecek P; Sullivan PF; Svenson KL; Weinstock GM; Threadgill DW; Pomp D; Churchill GA; Pardo-Manuel de Villena F. 2015. A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2. PLoS Genet 11(2):e1004850. PubMed: 25679959MGI: J:224006
- Ho MM; Hu X; Karunakaran S; Johnson JD; Clee SM. 2014. Altered pancreatic growth and insulin secretion in WSB/EiJ mice. PLoS One 9(2):e88352. PubMed: 24505481MGI: J:212961
- Keane TM; Goodstadt L; Danecek P; White MA; Wong K; Yalcin B; Heger A; Agam A; Slater G; Goodson M; Furlotte NA; Eskin E; Nellaker C; Whitley H; Cleak J; Janowitz D; Hernandez-Pliego P; Edwards A; Belgard TG; Oliver PL; McIntyre RE; Bhomra A; Nicod J; Gan X; Yuan W; van der Weyden L; Steward CA; Bala S; Stalker J; Mott R; Durbin R; Jackson IJ; Czechanski A; Guerra-Assuncao JA; Donahue LR; Reinholdt LG; Payseur BA; Ponting CP; Birney E; Flint J; Adams DJ. 2011. Mouse genomic variation and its effect on phenotypes and gene regulation. Nature 477(7364):289-94. PubMed: 21921910MGI: J:177037
- Odet F; Pan W; Bell TA; Goodson SG; Stevans AM; Yun Z; Aylor DL; Kao CY; McMillan L; de Villena FP; O'Brien DA. 2015. The Founder Strains of the Collaborative Cross Express a Complex Combination of Advantageous and Deleterious Traits for Male Reproduction. G3 (Bethesda) 5(12):2671-83. PubMed: 26483008MGI: J:244582
Additional - A related
- Blewitt ME; Vickaryous NK; Hemley SJ; Ashe A; Bruxner TJ; Preis JI; Arkell R; Whitelaw E. 2005. An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse. Proc Natl Acad Sci U S A 102(21):7629-34. PubMed: 15890782MGI: J:99816
- Bultman SJ; Michaud EJ; Woychik RP. 1992. Molecular characterization of the mouse agouti locus. Cell 71(7):1195-204. PubMed: 1473152MGI: J:3523
- Bundschuh VG; Madry M. 1988. [atwp mutation in an albino mouse substrain (AB/Hum-1)] Z Versuchstierkd 31(6):249-54. PubMed: 3227730MGI: J:16568
- Cota CD; Liu RR; Sumberac TM; Jung S; Vencato D; Millet YH; Gunn TM. 2008. Genetic and phenotypic studies of the dark-like mutant mouse. Genesis 46(10):562-73. PubMed: 18821597MGI: J:143333
- Czyzyk TA; Sikorski MA; Yang L; McKnight GS. 2008. Disruption of the RIIbeta subunit of PKA reverses the obesity syndrome of Agouti lethal yellow mice. Proc Natl Acad Sci U S A 105(1):276-81. PubMed: 18172198MGI: J:131039
- Dickie MM. 1969. Mutations at the agouti locus in the mouse. J Hered 60(1):20-5. PubMed: 5798139MGI: J:30922
- Dry FW. 1928. The agouti coloration of the mouse (Mus Musculus) and the rat (Mus Norvegicus). J Genet 20:131-144. MGI: J:46318
- Dunn LC. 1945. A New Eye Color Mutant in the Mouse with Asymmetrical Expression. Proc Natl Acad Sci U S A 31(11):343-6. PubMed: 16578176MGI: J:13122
- Galbraith DB; Wolff GL; Brewer NL. 1979. Tissue microenvironment and the genetic control of hair pigment patterns in mice Dev Genet 1(2):167-179. MGI: J:156092
- Green EL. 1968. . In: Handbook on Genetically Standardized Jax Mice. The Jackson Laboratory, Bar Harbor, ME. MGI: J:36414
- Guido V; and The Mouse Mutant Resource (MMR) at The Jackson Laboratory. 2002. Two new mutations of white bellied agouti, w-46J and w-47J MGI Direct Data Submission :. MGI: J:77218
- Jackson IJ; Budd PS; Keighren M; McKie L. 2007. Humanized MC1R transgenic mice reveal human specific receptor function. Hum Mol Genet 16(19):2341-8. PubMed: 17652101MGI: J:129904
- Kelly EM. 1957. Beige, bg Mouse News Lett 16:36. MGI: J:29744
- Mather K; North SB. 1940. Umbrous: a case of dominance modification in mice. J Genet 40:229-41. MGI: J:280
- MouseBookTM. 2005. Information obtained from MouseBook<sup>TM</sup>, Medical Research Council Mammalian Genetics Unit, Harwell, UK. Unpublished :. MGI: J:169366
- Mutant Mouse Regional Resource Centers. 2004. Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC) Unpublished :. MGI: J:94077
- Perry WL; Copeland NG; Jenkins NA. 1994. The molecular basis for dominant yellow agouti coat color mutations. Bioessays 16(10):705-7. PubMed: 7980472MGI: J:21244
- Phillips RJS. 1966. A cis-trans position effect at the A locus of the house mouse. Genetics 54(2):485-95. PubMed: 5968639MGI: J:5027
- Quevedo WC Jr.; Chase HB. 1958. An analysis of the light mutation of coat color in mice. J Morphol 102:329-345. MGI: J:13094
- Silvers WK. 1979. The Coat Colors of Mice; A Model for Mammalian Gene Action and Interaction. In: The Coat Colors of Mice. Springer-Verlag, New York. MGI: J:78801
- Siracusa LD; Washburn LL; Swing DA; Argeson AC; Jenkins NA; Copeland NG. 1995. Hypervariable yellow (Ahvy), a new murine agouti mutation: Ahvy displays the largest variation in coat color phenotypes of all known agouti alleles. J Hered 86(2):121-8. PubMed: 7751596MGI: J:24247
- Zheng B; Sage M; Cai WW; Thompson DM; Tavsanli BC; Cheah YC; Bradley A. 1999. Engineering a mouse balancer chromosome. Nat Genet 22(4):375-8. PubMed: 10431243MGI: J:56548
- von Lehmann E. 1973. Coat colour genetics of the tobacco-mouse (Mus poschiavinus Fatio) Mouse News Lett 48:23. MGI: J:22593
Additional - Kitlsl-blz related
- Aylor DL; Valdar W; Foulds-Mathes W; Buus RJ; Verdugo RA; Baric RS; Ferris MT; Frelinger JA; Heise M; Frieman MB; Gralinski LE; Bell TA; Didion JD; Hua K; Nehrenberg DL; Powell CL; Steigerwalt J; Xie Y; Kelada SN; Collins FS; Yang IV; Schwartz DA; Branstetter LA; Chesler EJ; Miller DR; Spence J; Liu EY; McMillan L; Sarkar A; Wang J; Wang W; Zhang Q; Broman KW; Korstanje R; Durrant C; Mott R; Iraqi FA; Pomp D; Threadgill D; de Villena FP; Churchill GA. 2011. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res 21(8):1213-22. PubMed: 21406540MGI: J:169740
- Washburn LL; Harris BS. 2010. The recessive mutation blaze (blz) that characterizes the WSB/EiJ strain is an allele of Kitl, Kitl<blz> Personal Communication :. MGI: J:179958