In(X)1H is a long paracentric inversion involving approximately 85% of the X Chromosome with the proximal breakpoint originally reported by Evans and Phillips (1975) to be just within the dark centric band A1 and the distal breakpoint found distal to band E. This strain can be maintained by breeding homozygous females with hemizygous males, but litter size is smaller than normal. When breeding involves heterozygous females there is a significant number of X/O mice produced because of meiotic non-disjunction. O/Y are not viable in mice, but X/O generally are. This strain is valuable in the study of chromosomal pairing, meiotic non-disjunction, imprinting and X Chromosome inactivation, as well the generation of X/O mice which can model Turner syndrome.

In(X)1H is a long inversion in the X Chromosome that is valuable in the study of chromosomal pairing, meiotic non-disjunction, imprinting and X Chromosome inactivation, as well the generation of X/O mice which can model Turner syndrome.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

<a target="_blank" href="https://www.jax.org/jax-mice-and-services/customer-support" rel="noreferrer">Contact Customer Service</a> for more information.