JAX Mouse Strain Datasheet - 000679

P/J

Stock No:: 000679

Inbred Strain

Cryo Recovery

Overview

P/J mice exhibit a high incidence of lymphatic leukaemia. They also show a high susceptibility to audiogenic and electroconvulsive seizures. P/J mice are also homozygous for a number of other mutations including nonagouti (a), brown (Tyrp1^b), pink-eyed dilution (Oca2^p), short ear (Bmp5^se), dilute Myo5a^d), and retinal degeneration 1 (Pdeb1^rd1

Genetic overview

Genetic Background	Generation

View Genetics

Research Applications

Cancer Research
Dermatology Research
Developmental Biology Research
Neurobiology Research
Sensorineural Research

View All Research Applications

Base Price

Starting at:

$2,595.00 Domestic price Cryo Recovery

View Price List

Details

Important Note

This strain is homozygous for Cdh23^ahl, the age related hearing loss 1 mutation, which on this background results in progressive hearing loss with onset after 10 months of age. This strain is also homozygous for the retinal degeneration allele Pde6b^rd1. See article "Genetic Background Effects: Can Your Mice See?", JAX^® NOTES Spring 2002, No. 485.

Detailed Description

Development

The P/J inbred strain was created by G.D. Snell by extracting the genes a, Tyrp1^b (originally b), Myo5a^d (originally d), Bmp5^se (originally se), Oca2^p (originally p), Pde6b (originally rd) from strain BDP, developed by W. H. Gates, following an outcross.

Selected References

Petkov PM; Cassell MA; Sargent EE; Donnelly CJ; Robinson P; Crew V; Asquith S; Haar RV; Wiles MV. 2004. Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse. Genomics 83(5):902-11. PubMed: 15081119 MGI: J:89298

View All References

Genetics

Ahr^b-2

Allele Symbol: Ahr^b-2

Allele Name	b-2 variant
Allele Type	Not Applicable
Allele Synonym(s)	Ah^b-2; Ah^h
Gene Symbol and Name	Ahr, aryl-hydrocarbon receptor
Gene Synonym(s)	Ah; Ahh; Ahre; In; aromatic hydrocarbon responsiveness; aryl hydrocarbon hydroxylase; bHLHe76; dioxin receptor; inflammatory reactivity
Strain of Origin	BALB/cBy
Chromosome	12
General Note	C57BL/6 carries the responsive Ahr^b allele; DBA/2 carries nonresponsive Ahr^d. Heterozygotes (Ahr^b/Ahr^d) are responsive (J:5282). Later work identified a second (J:8895) and later a third (J:22144) allele conferring response. Thus the allele in C57, C58, and MA/My strains is now Ahr^b-1; Ahr^b-2 is carried by BALB/cBy, A, and C3H; and Ahr^b-3 by Mus spretus, M. caroli, and MOLF/Ei. The nonresponsive strains AKR, DBA/2, and 129 carry Ahrd (J:22144). Nucleotide and amino acid sequence differences between Ahr^b-1 and Ahr^d have been determined (J:17460). Strain of origin - this allele was found in BALB/cByJ, A/J, C3H/HeJ, CBA strains
Molecular Note	This allele encodes a high affinity, heat labile, 104 kDa receptor containing 848 amino acids. Sequencing studies of cDNA from C57BL/6J congenic mice homozygous for this allele identified nucleotide substitutions in the ORF that would cause 5 amino acid differences between the C57BL/6J and BALB/cBy peptides, and 2 amino acid differences between the BALB/cBy and DBA/2J peptides. A T to C transition in exon 11 replaces the opal termination codon in the C57BL/6J allele with an arginine codon in the BALB/cBy allele. This change would extend translation of the BALB/cBy mRNA by 43 amino acids, accounting for the larger size of the peptide produced by this allele (104 kDa, vs 95 kDa for the C57BL/6J allele).

Bmp5^se

Allele Symbol: Bmp5^se

Allele Name	short ear
Allele Type	Spontaneous
Allele Synonym(s)	se^GnJ
Gene Symbol and Name	Bmp5, bone morphogenetic protein 5
Gene Synonym(s)	AU023399; expressed sequence AU023399; se; short ear
Strain of Origin	mice from Abbie Lathrop mouse farm
Chromosome	9
General Note	Phenotypic Similarity to Human Syndrome: Ear, Patella, Short Stature Syndrome (Meier-Gorlin Syndrome) in homozygous mice (J:24474)
Molecular Note	The C to T transition creates a stop codon at amino acid 208. The resulting truncated protein does not include the carboxy terminal signaling portion of the molecule.

Cdh23^ahl

Allele Symbol: Cdh23^ahl

Allele Name	age related hearing loss 1
Allele Type	Spontaneous
Allele Synonym(s)	Cdh23^753A; mdfw
Gene Symbol and Name	Cdh23, cadherin 23 (otocadherin)
Gene Synonym(s)	4930542A03Rik; 4930542A03Rik; CDHR23; RIKEN cDNA 4930542A03 gene; USH1D; W; age related hearing loss 1; ahl; ahl; bob; bob; bobby; bus; bustling; mdfw; mdfw; modifier of deaf waddler; neuroscience mutagenesis facility, 112; neuroscience mutagenesis facility, 181; neuroscience mutagenesis facility, 252; nmf112; nmf112; nmf181; nmf181; nmf252; nmf252; sals; sals; salsa; v; waltzer
Strain of Origin	multiple strains
Chromosome	10
Molecular Note	Genetic complementation tests have shown allelism between the mdfw (modifier of deaf waddler) locus and the ahl locus. Further analysis has shown this is caused by a G to A transition at nucleotide position 753 of Cdh23. This hypomorphic allele causes in frame skipping of exon 7, which is predicted to delete part of the 2nd and 3rd ectodomains, and cause reduced message stability. Twenty-seven strains classified with ahl and carrying the 753A allele include: CD1, RBF/DnJ, PL/J, AKR/J, RF/J, BALB/cBy, A/WySnJ, P/J, SENCARA/PtJ, DBA/1J, ALS/LtJ, C58/J, C57BLKS/J, 129P1/ReJ, C57BR/cd, SKH2/J, BUB/Bn, MA/MyJ, LP/J, 129X1/SvJ, NOR/LtJ, A/J, C57BL/6, NOD/LtJ, DBA/2J, ALR/LtJ, C57L/J. Strains classified with ahl that DO NOT carry this mutation include: C3H/HeSnJ, I/LnJ, YBR/Ei, MRL/MpJ.

Gpr84^del

Allele Symbol: Gpr84^del

Allele Name	deletion
Allele Type	Spontaneous (Not Specified)
Allele Synonym(s)
Gene Symbol and Name	Gpr84, G protein-coupled receptor 84
Gene Synonym(s)	EX33; GPCR4
Strain of Origin	multiple strains
Chromosome	15
Molecular Note	This spontaneously arising frameshift deletion is located in exon 2 at position 103308576 bp (NCBI Build 37) and results in a premature stop codon. The mutation is predicted to result in a truncated protein lacking the transmembrane domains 4-7. The inbred strains BDP/J, DBA/1J, DBA/2J, I/LnJ, FVB/NJ, LG/J, MRL/MpJ, NODShi/LtJ, NOR/LtJ, P/J, PL/J, SKHIN/Sprd, SJL/J, SM/J are homozygous for the deletion. The allele is segregating in the outbred stocks ICR and CD-1.

Myo5a^d

Allele Symbol: Myo5a^d

Allele Name	dilute
Allele Type	Spontaneous
Allele Synonym(s)	Maltese dilution; blue dilution; d; d^v
Gene Symbol and Name	Myo5a, myosin VA
Gene Synonym(s)	9630007J19Rik; 9630007J19Rik; AI413174; AI661011; D; Dbv; Dbv; Dop; GS1; MVa; MYH12; MYO5; MYR12; Myh12; Myo5; Myo5; MyoVA; RIKEN cDNA 9630007J19 gene; d; dilute; expressed sequence AI413174; expressed sequence AI661011; flail; flail; flailer; flr; myosin V; nmf244
Strain of Origin	old mutant of the mouse fancy
Chromosome	9
Molecular Note	This mutation is the result of the integration of ecotropic murine leukemia virus Emv-3 into a noncoding region of the Myo5a^d gene. Reversions of Myo5a^d to wild-type are caused by excision of the virus leaving exactly one long terminal repeat in place.

Pde6b^rd1

Allele Symbol: Pde6b^rd1

Allele Name	retinal degeneration 1
Allele Type	Spontaneous
Allele Synonym(s)	Pdeb^rd1; rd; rd-1; rd1; rodless retina
Gene Symbol and Name	Pde6b, phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide
Gene Synonym(s)	CSNB3; CSNBAD2; GMP-PDEbeta; PDEB; Pdeb; Pdeb; RP40; nmf137; phosphodiesterase, cGMP, rod receptor, beta polypeptide; r; r; rd; rd; rd-1; rd1; rd1; rd10; rd10; retinal degeneration; retinal degeneration 1; retinal degeneration 10
Strain of Origin	various
Chromosome	5
General Note	The following inbred strains are known to be homozygous for Pde6b: C3H sublines, CBA/J, FVB/NJ, PL/J, SB, SJL/J, and SWR/J.
Molecular Note	Two mutations have been identified in rd1 mice. A murine leukimia virus (Xmv-28) insertion in reverse orientation in intron 1 is found in all mouse strains with the rd1 phenotype. Further, a nonsense mutation (C to A transversion) in codon 347 that results in a truncation eliminating more than half of the predicted encoded protein, including the catalytic domain has also been identified in all rd1 strains of mice. A specific degradation of mutant transcript during or after pre-mRNA splicing is suggested.

Disease/Phenotype

Disease Terms

Research Areas By Genotype

This mouse can be used to support research in many areas including:

Cancer Research
- Increased Tumor Incidence
  - Leukemia
Dermatology Research
- Color and White Spotting Defects
Developmental Biology Research
- Growth Defects
- Skeletal Defects
Neurobiology Research
- Angelman syndrome
- Epilepsy
  - audiogenic seizures
  - electroconvulsive seizures
- Hearing Defects
  - Age related hearing loss
Sensorineural Research
- Hearing Defects
  - Age related hearing loss
- Retinal Degeneration
  - Homozygous for Pde6b^rd1

Genotype: Bmp5^se related

Developmental Biology Research
- Craniofacial and Palate Defects
- Growth Defects
- Skeletal Defects

Genotype: Cdh23^ahl related

Neurobiology Research
- Hearing Defects
  - Age related hearing loss
Sensorineural Research
- Hearing Defects
  - Age related hearing loss

Genotype: Myo5a^d related

Dermatology Research
- Color and White Spotting Defects

Genotype: Pde6b^rd1 related

Sensorineural Research
- Retinal Degeneration

Phenotype Information

Festing Inbred Strain Characteristics: P

References

Petkov PM; Cassell MA; Sargent EE; Donnelly CJ; Robinson P; Crew V; Asquith S; Haar RV; Wiles MV. 2004. Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse. Genomics 83(5):902-11. PubMed: 15081119 MGI: J:89298

Additional References

Deckard BS; Lieff B; Schlesinger K; DeFries JC. 1976. Developmental patterns of seizure susceptibility in inbred strains of mice. Dev Psychobiol 9(1):17-24. PubMed: 1254102 MGI: J:25363
Hoag WG. 1963. Spontaneous cancer in mice Ann N Y Acad Sci 108:805-831. PubMed: 14081516 MGI: J:2434
Poland A; Glover E. 1990. Characterization and strain distribution pattern of the murine Ah receptor specified by the Ahd and Ahb-3 alleles. Mol Pharmacol 38(3):306-12. PubMed: 2169579 MGI: J:34840
Xie C; Sharma R; Wang H; Zhou XJ; Mohan C. 2004. Strain distribution pattern of susceptibility to immune-mediated nephritis. J Immunol 172(8):5047-55. PubMed: 15067087 MGI: J:122988
Zheng QY; Johnson KR; Erway LC. 1999. Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses. Hear Res 130(1-2):94-107. PubMed: 10320101 MGI: J:54812

Additional - Ahr^b-2 related

Nebert DW; Considine N; Owens IS. 1973. Genetic expression of aryl hydrocarbon hydroxylase induction. VI. Control of other aromatic hydrocarbon-inducible mono-oxygenase activities at or near the same genetic locus. Arch Biochem Biophys 157(1):148-59. PubMed: 4716952 MGI: J:84313
Nebert DW; Gielen JE. 1972. Genetic regulation of aryl hydrocarbon hydroxylase induction in the mouse. Fed Proc 31(4):1315-25. PubMed: 4114109 MGI: J:5282
Nebert DW; Jensen NM; Shinozuka H; Kunz HW; Gill TJ 3rd. 1982. The Ah phenotype. Survey of forty-eight rat strains and twenty inbred mouse strains. Genetics 100(1):79-87. PubMed: 7095422 MGI: J:6809
Nebert DW; Robinson JR; Niwa A; Kumaki K; Poland AP. 1975. Genetic expression of aryl hydrocarbon hydroxylase activity in the mouse. J Cell Physiol 85(2 Pt 2 Suppl 1):393-414. PubMed: 1091656 MGI: J:84317
Niwa A; Kumaki K; Nebert DW; Poland AP. 1975. Genetic expression of aryl hydrocarbon hydroxylase activity in the mouse. Distinction between the 'responsive' homozygote and heterozygote at the Ah locus. Arch Biochem Biophys 166(2):559-64. PubMed: 1119809 MGI: J:84316
Poland A; Glover E. 1990. Characterization and strain distribution pattern of the murine Ah receptor specified by the Ahd and Ahb-3 alleles. Mol Pharmacol 38(3):306-12. PubMed: 2169579 MGI: J:34840
Poland A; Glover E; Taylor BA. 1987. The murine Ah locus: a new allele and mapping to chromosome 12. Mol Pharmacol 32(4):471-8. PubMed: 2823093 MGI: J:8895
Poland A; Palen D; Glover E. 1994. Analysis of the four alleles of the murine aryl hydrocarbon receptor. Mol Pharmacol 46(5):915-21. PubMed: 7969080 MGI: J:22144
Robinson JR; Considine N; Nebert DW. 1974. Genetic expression of aryl hydrocarbon hydroxylase induction. Evidence for the involvement of other genetic loci. J Biol Chem 249(18):5851-9. PubMed: 4413562 MGI: J:84315
Schmid FA; Pena RC; Robinson W; Tarnowski GS. 1967. Toxicity of intraperitoneal injections of 7, 12-dimethylbenz[a]anthracene in inbred mice. Cancer Res 27(3):558-62. PubMed: 6021513 MGI: J:26440
Schmidt JV; Carver LA; Bradfield CA. 1993. Molecular characterization of the murine Ahr gene. Organization, promoter analysis, and chromosomal assignment. J Biol Chem 268(29):22203-9. PubMed: 8408082 MGI: J:15153
Smith AG; Clothier B; Robinson S; Scullion MJ; Carthew P; Edwards R; Luo J; Lim CK; Toledano M. 1998. Interaction between iron metabolism and 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice with variants of the Ahr gene: a hepatic oxidative mechanism. Mol Pharmacol 53(1):52-61. PubMed: 9443932 MGI: J:45850
Thomas PE; Hutton JJ; Taylor BA. 1973. Genetic relationship between aryl hydrocarbon hydroxylase inducibility and chemical carcinogen induced skin ulceration in mice. Genetics 74(4):655-9. PubMed: 4750810 MGI: J:5387

Additional - Bmp5^se related

Cattanach BM. 1961. A chemically-induced variegated-type position effect in the mouse. Z Vererbungsl 92:165-82. PubMed: 13877379 MGI: J:160128
Deol MS; Green MC. 1966. Snell's waltzer, a new mutation affecting behaviour and the inner ear in the mouse. Genet Res 8(3):339-45. PubMed: 5980120 MGI: J:5044
DiLeone RJ; Russell LB; Kingsley DM. 1998. An extensive 3' regulatory region controls expression of Bmp5 in specific anatomical structures of the mouse embryo. Genetics 148(1):401-8. PubMed: 9475750 MGI: J:45426
GREEN MC. 1958. Effects of the short ear gene in the mouse on cartilage formation in healing bone fractures. J Exp Zool 137(1):75-88. PubMed: 13563786 MGI: J:13011
Green EL; Green MC. 1946. Effect of the short ear gene on number of ribs and presacral vertebrae in the house mouse Am Naturalist 80:619-25. MGI: J:100198
Green EL; Green MC. 1942. The development of three manifestations of the short ear gene in the mouse J Morphol 70:1-19. MGI: J:15478
Green MC. 1968. Mechanism of the pleiotropic effects of the short-ear mutant gene in the mouse. J Exp Zool 167(2):129-50. PubMed: 5692092 MGI: J:5086
Green MC. 1951. Further morphological effects of the short ear gene in the house mouse. J Morphol 88:1-22. MGI: J:13091
Hashimoto M; Morita H; Ueno N. 2014. Molecular and cellular mechanisms of development underlying congenital diseases. Congenit Anom (Kyoto) 54(1):1-7. PubMed: 24666178 MGI: J:209580
Johnson DR. 1976. The interfrontal bone and mutant genes in the mouse. J Anat 121(3):507-13. PubMed: 1018005 MGI: J:5776
Jones JM; Huang JD; Mermall V; Hamilton BA; Mooseker MS; Escayg A; Copeland NG; Jenkins NA; Meisler MH. 2000. The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5a. Hum Mol Genet 9(5):821-8. PubMed: 10749990 MGI: J:61324
Kangsamaksin T; Morris RJ. 2011. Bone morphogenetic protein 5 regulates the number of keratinocyte stem cells from the skin of mice. J Invest Dermatol 131(3):580-5. PubMed: 21179110 MGI: J:182086
Katagiri T; Boorla S; Frendo JL; Hogan BL; Karsenty G. 1998. Skeletal abnormalities in doubly heterozygous Bmp4 and Bmp7 mice. Dev Genet 22(4):340-8. PubMed: 9664686 MGI: J:48538
King JA; Marker PC; Seung KJ; Kingsley DM. 1994. BMP5 and the molecular, skeletal, and soft-tissue alterations in short ear mice. Dev Biol 166(1):112-22. PubMed: 7958439 MGI: J:21484
Kingsley DM; Bland AE; Grubber JM; Marker PC; Russell LB; Copeland NG; Jenkins NA. 1992. The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGF beta superfamily. Cell 71(3):399-410. PubMed: 1339316 MGI: J:3046
Lacombe D; Toutain A; Gorlin RJ; Oley CA; Battin J. 1994. Clinical identification of a human equivalent to the short ear (se) murine phenotype. Ann Genet 37(4):184-91. PubMed: 7710253 MGI: J:24474
Lynch CJ. 1921. Short ears, an autosomal mutation in the house mouse Am Naturalist 55:421-426. MGI: J:14849
Nadeau JH. 2001. Modifier genes in mice and humans. Nat Rev Genet 2(3):165-74. PubMed: 11256068 MGI: J:88013
Oak Ridge National Laboratory. 2005. Information obtained from the Oak Ridge National Laboratory Mutant Mouse Database (ORNL), Oak Ridge, TN Unpublished :. MGI: J:100221
Pfendler KC; Yoon J; Taborn GU; Kuehn MR; Iannaccone PM. 2000. Nodal and bone morphogenetic protein 5 interact in murine mesoderm formation and implantation. Genesis 28(1):1-14. PubMed: 11020711 MGI: J:65690
Russell LB. 1971. Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res 11(1):107-23. PubMed: 5556347 MGI: J:12013
Sloane JA; Vartanian TK. 2007. Myosin Va controls oligodendrocyte morphogenesis and myelination. J Neurosci 27(42):11366-75. PubMed: 17942731 MGI: J:126066
Solloway MJ; Dudley AT; Bikoff EK; Lyons KM; Hogan BL; Robertson EJ. 1998. Mice lacking Bmp6 function. Dev Genet 22(4):321-39. PubMed: 9664685 MGI: J:48561
Solloway MJ; Robertson EJ. 1999. Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. Development 126(8):1753-68. PubMed: 10079236 MGI: J:53294
The Mammalian Genetics Unit at Harwell. 2004. Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK Unpublished :. MGI: J:90559
Tilleman H; Hakim V; Novikov O; Liser K; Nashelsky L; Di Salvio M; Krauthammer M; Scheffner O; Maor I; Mayseless O; Meir I; Kayam G; Sela-Donenfeld D; Simeone A; Brodski C. 2010. Bmp5/7 in concert with the mid-hindbrain organizer control development of noradrenergic locus coeruleus neurons. Mol Cell Neurosci 45(1):1-11. PubMed: 20493948 MGI: J:171333

Additional - Cdh23^ahl related

Bosco A; Crish SD; Steele MR; Romero CO; Inman DM; Horner PJ; Calkins DJ; Vetter ML. 2012. Early reduction of microglia activation by irradiation in a model of chronic glaucoma. PLoS One 7(8):e43602. PubMed: 22952717 MGI: J:191663
Davis RR; Newlander JK; Ling X; Cortopassi GA; Krieg EF; Erway LC. 2001. Genetic basis for susceptibility to noise-induced hearing loss in mice. Hear Res 155(1-2):82-90. PubMed: 11335078 MGI: J:69679
Di Palma F; Pellegrino R; Noben-Trauth K. 2001. Genomic structure, alternative splice forms and normal and mutant alleles of cadherin 23 (Cdh23). Gene 281(1-2):31-41. PubMed: 11750125 MGI: J:73941
Fetoni AR; Picciotti PM; Paludetti G; Troiani D. 2011. Pathogenesis of presbycusis in animal models: a review. Exp Gerontol 46(6):413-25. PubMed: 21211561 MGI: J:186964
Han F; Yu H; Tian C; Chen HE; Benedict-Alderfer C; Zheng Y; Wang Q; Han X; Zheng QY. 2010. A new mouse mutant of the Cdh23 gene with early-onset hearing loss facilitates evaluation of otoprotection drugs. Pharmacogenomics J :. PubMed: 20644563 MGI: J:174758
Hurd EA; Adams ME; Layman WS; Swiderski DL; Beyer LA; Halsey KE; Benson JM; Gong TW; Dolan DF; Raphael Y; Martin DM. 2011. Mature middle and inner ears express Chd7 and exhibit distinctive pathologies in a mouse model of CHARGE syndrome. Hear Res 282(1-2):184-95. PubMed: 21875659 MGI: J:220430
Johnson KR; Erway LC; Cook SA; Willott JF; Zheng QY. 1997. A major gene affecting age-related hearing loss in C57BL/6J mice Hear Res 114(1-2):83-92. PubMed: 9447922 MGI: J:44966
Johnson KR; Longo-Guess C; Gagnon LH; Yu H; Zheng QY. 2008. A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice. Genomics 92(4):219-25. PubMed: 18662770 MGI: J:139223
Johnson KR; Tian C; Gagnon LH; Jiang H; Ding D; Salvi R. 2017. Effects of Cdh23 single nucleotide substitutions on age-related hearing loss in C57BL/6 and 129S1/Sv mice and comparisons with congenic strains. Sci Rep 7:44450. PubMed: 28287619 MGI: J:241137
Johnson KR; Yu H; Ding D; Jiang H; Gagnon LH; Salvi RJ. 2010. Separate and combined effects of Sod1 and Cdh23 mutations on age-related hearing loss and cochlear pathology in C57BL/6J mice. Hear Res 268(1-2):85-92. PubMed: 20470874 MGI: J:163035
Johnson KR; Zheng QY; Bykhovskaya Y; Spirina O; Fischel-Ghodsian N. 2001. A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice. Nat Genet 27(2):191-4. PubMed: 11175788 MGI: J:67312
Johnson KR; Zheng QY; Noben-Trauth K. 2006. Strain background effects and genetic modifiers of hearing in mice. Brain Res 1091(1):79-88. PubMed: 16579977 MGI: J:110459
Johnson KR; Zheng QY; Weston MD; Ptacek LJ; Noben-Trauth K. 2005. The Mass1(frings) mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC. Genomics 85(5):582-90. PubMed: 15820310 MGI: J:97534
Kane KL; Longo-Guess CM; Gagnon LH; Ding D; Salvi RJ; Johnson KR. 2012. Genetic background effects on age-related hearing loss associated with Cdh23 variants in mice. Hear Res 283(1-2):80-8. PubMed: 22138310 MGI: J:183757
Keithley EM; Canto C; Zheng QY; Fischel-Ghodsian N; Johnson KR. 2004. Age-related hearing loss and the ahl locus in mice. Hear Res 188(1-2):21-8. PubMed: 14759567 MGI: J:87783
Liu X; Bulgakov OV; Darrow KN; Pawlyk B; Adamian M; Liberman MC; Li T. 2007. Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells. Proc Natl Acad Sci U S A 104(11):4413-8. PubMed: 17360538 MGI: J:118927
Manji SS; Williams LH; Miller KA; Ooms LM; Bahlo M; Mitchell CA; Dahl HH. 2011. A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart. PLoS One 6(3):e17607. PubMed: 21423608 MGI: J:171701
Mathews CE; Leiter EH. 1999. Resistance of ALR/Lt islets to free radical-mediated diabetogenic stress is inherited as a dominant trait. Diabetes 48(11):2189-96. PubMed: 10535453 MGI: J:109893
Murillo-Cuesta S; Rodriguez-de la Rosa L; Contreras J; Celaya AM; Camarero G; Rivera T; Varela-Nieto I. 2015. Transforming growth factor beta1 inhibition protects from noise-induced hearing loss. Front Aging Neurosci 7:32. PubMed: 25852546 MGI: J:242536
Nadeau JH. 2003. Modifier genes and protective alleles in humans and mice. Curr Opin Genet Dev 13(3):290-5. PubMed: 12787792 MGI: J:88012
Nagtegaal AP; Rainey RN; van der Pluijm I; Brandt RM; van der Horst GT; Borst JG; Segil N. 2015. Cockayne syndrome group B (csb) and group a (csa) deficiencies predispose to hearing loss and cochlear hair cell degeneration in mice. J Neurosci 35(10):4280-6. PubMed: 25762674 MGI: J:219993
Noben-Trauth K; Latoche JR; Neely HR; Bennett B. 2010. Phenotype and genetics of progressive sensorineural hearing loss (Snhl1) in the LXS set of recombinant inbred strains of mice. PLoS One 5(7):e11459. PubMed: 20628639 MGI: J:163117
Noben-Trauth K; Zheng QY; Johnson KR. 2003. Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss. Nat Genet 35(1):21-3. PubMed: 12910270 MGI: J:86905
Noben-Trauth K; Zheng QY; Johnson KR; Nishina PM. 1997. mdfw: a deafness susceptibility locus that interacts with deaf waddler (dfw). Genomics 44(3):266-72. PubMed: 9325047 MGI: J:38429
Perrin BJ; Sonnemann KJ; Ervasti JM. 2010. beta-actin and gamma-actin are each dispensable for auditory hair cell development but required for Stereocilia maintenance. PLoS Genet 6(10):e1001158. PubMed: 20976199 MGI: J:167543
Perrin BJ; Strandjord DM; Narayanan P; Henderson DM; Johnson KR; Ervasti JM. 2013. beta-Actin and Fascin-2 Cooperate to Maintain Stereocilia Length. J Neurosci 33(19):8114-21. PubMed: 23658152 MGI: J:197137
Vazquez AE; Jimenez AM; Martin GK; Luebke AE; Lonsbury-Martin BL. 2004. Evaluating cochlear function and the effects of noise exposure in the B6.CAST+Ahl mouse with distortion product otoacoustic emissions. Hear Res 194(1-2):87-96. PubMed: 15276680 MGI: J:117746
Watson CJ; Tempel BL. 2013. A new Atp2b2 deafwaddler allele, dfw(i5), interacts strongly with Cdh23 and other auditory modifiers. Hear Res 304:41-8. PubMed: 23792079 MGI: J:220660
Zheng QY; Johnson KR. 2001. Hearing loss associated with the modifier of deaf waddler (mdfw) locus corresponds with age-related hearing loss in 12 inbred strains of mice. Hear Res 154(1-2):45-53. PubMed: 11423214 MGI: J:70964
Zheng QY; Scarborough JD; Zheng Y; Yu H; Choi D; Gillespie PG. 2012. Digenic inheritance of deafness caused by 8J allele of myosin-VIIA and mutations in other Usher I genes. Hum Mol Genet 21(11):2588-98. PubMed: 22381527 MGI: J:183898
Zilberstein Y; Liberman MC; Corfas G. 2012. Inner hair cells are not required for survival of spiral ganglion neurons in the adult cochlea. J Neurosci 32(2):405-10. PubMed: 22238076 MGI: J:179911

Additional - Gpr84^del related

Perez CJ; Dumas A; Vallieres L; Guenet JL; Benavides F. 2013. Several classical mouse inbred strains, including DBA/2, NOD/Lt, FVB/N, and SJL/J, carry a putative loss-of-function allele of Gpr84. J Hered 104(4):565-71. PubMed: 23616478 MGI: J:237405

Additional - Myo5a^d related

Cattanach BM. 1961. A chemically-induced variegated-type position effect in the mouse. Z Vererbungsl 92:165-82. PubMed: 13877379 MGI: J:160128
Coleman DL. 1962. Effect of genic substitution on the incorporation of tyrosine into the melanin of mouse skin. Arch Biochem Biophys 96:562-8. PubMed: 13880466 MGI: J:12173
Copeland NG; Hutchison KW; Jenkins NA. 1983. Excision of the DBA ecotropic provirus in dilute coat-color revertants of mice occurs by homologous recombination involving the viral LTRs. Cell 33(2):379-87. PubMed: 6305507 MGI: J:7092
Engle LJ; Kennett RH. 1994. Cloning, analysis, and chromosomal localization of myoxin (MYH12), the human homologue to the mouse dilute gene. Genomics 19(3):407-16. PubMed: 8188282 MGI: J:16915
Goodwins IR; Vincent MAC. 1955. Further data on linkage between short-ear and Maltese dilution in the house mouse Heredity 9:413-4. MGI: J:259
Grobman AB; Charles DR. 1947. Mutant white mice. A new dominant autosomal mutant affecting coat color in Mus musculus. J Hered 38:381-384. MGI: J:13058
Hearing VJ; Phillips P; Lutzner MA. 1973. The fine structure of melanogenesis in coat color mutants of the mouse. J Ultrastruct Res 43(1):88-106. PubMed: 4634048 MGI: J:5346
Hutchison KW; Copeland NG; Jenkins NA. 1984. Dilute-coat-color locus of mice: nucleotide sequence analysis of the d+2J and d+Ha revertant alleles. Mol Cell Biol 4(12):2899-904. PubMed: 6098826 MGI: J:7751
Jenkins NA; Copeland NG; Taylor BA; Lee BK. 1981. Dilute (d) coat colour mutation of DBA/2J mice is associated with the site of integration of an ecotropic MuLV genome. Nature 293(5831):370-4. PubMed: 6268990 MGI: J:6587
Jenkins NA; Copeland NG; Taylor BA; Lee BK. 1982. Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus. J Virol 43(1):26-36. PubMed: 6287001 MGI: J:6844
Libby RT; Lillo C; Kitamoto J; Williams DS; Steel KP. 2004. Myosin Va is required for normal photoreceptor synaptic activity. J Cell Sci 117(Pt 19):4509-15. PubMed: 15316067 MGI: J:92181
Markert CL; Silvers WK. 1956. The Effects of Genotype and Cell Environment on Melanoblast Differentiation in the House Mouse. Genetics 41(3):429-50. PubMed: 17247639 MGI: J:12970
Medical Research Council (MRC) Harwell. 2012. Direct Data Submission 2012/01/05 MGI Direct Data Submission :. MGI: J:178968
Medical Research Council (MRC) Harwell. 2012. Direct Data Submission 2012/01/18 MGI Direct Data Submission :. MGI: J:179353
Mercer JA; Seperack PK; Strobel MC; Copeland NG; Jenkins NA. 1991. Novel myosin heavy chain encoded by murine dilute coat colour locus [published erratum appears in Nature 1991 Aug 8;352(6335):547] Nature 349(6311):709-13. PubMed: 1996138 MGI: J:11005
Moore KJ; Swing DA; Copeland NG; Jenkins NA. 1994. The murine dilute suppressor gene encodes a cell autonomous suppressor. Genetics 138(2):491-7. PubMed: 7828830 MGI: J:20796
Moore KJ; Swing DA; Copeland NG; Jenkins NA. 1990. Interaction of the murine dilute suppressor gene (dsu) with fourteen coat color mutations [published erratum appears in Genetics 1990 Sep;126(1):285] Genetics 125(2):421-30. PubMed: 2379821 MGI: J:29467
Moore KJ; Swing DA; Rinchik EM; Mucenski ML; Buchberg AM; Copeland NG; Jenkins NA. 1988. The murine dilute suppressor gene dsu suppresses the coat-color phenotype of three pigment mutations that alter melanocyte morphology, d, ash and ln. Genetics 119(4):933-41. PubMed: 3410303 MGI: J:9309
MouseBook^TM. 2005. Information obtained from MouseBook<sup>TM</sup>, Medical Research Council Mammalian Genetics Unit, Harwell, UK. Unpublished :. MGI: J:169366
Murray WS. 1934. The breeding behavior of the dilute brown stock of mice (Little dba) Am J Cancer 20:573-593. MGI: J:2464
O'Sullivan TN; Wu XS; Rachel RA; Huang JD; Swing DA; Matesic LE; Hammer JA 3rd; Copeland NG; Jenkins NA. 2004. dsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice. Proc Natl Acad Sci U S A 101(48):16831-6. PubMed: 15550542 MGI: J:94728
PIERRO LJ; CHASE HB. 1963. Slate--a new coat color mutant in the mouse. J Hered 54:47-50. PubMed: 13943454 MGI: J:25388
Pastural E; Barrat FJ; Dufourcq-Lagelouse R; Certain S; Sanal O ; Jabado N ; Seger R ; Griscelli C ; Fischer A ; de Saint Basile G. 1997. Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene. Nat Genet 16(3):289-92. PubMed: 9207796 MGI: J:41253
Provance DW Jr; Wei M; Ipe V; Mercer JA. 1996. Cultured melanocytes from dilute mutant mice exhibit dendritic morphology and altered melanosome distribution. Proc Natl Acad Sci U S A 93(25):14554-8. PubMed: 8962090 MGI: J:37976
Quevedo WC Jr.; Chase HB. 1958. An analysis of the light mutation of coat color in mice. J Morphol 102:329-345. MGI: J:13094
RIKEN BioResource Center/RIKEN Genomic Sciences Center. 2008. A Large Scale Mutagenesis Program in RIKEN GSC PhenoSITE, World Wide Web (URL: http://www.brc.riken.jp/lab/gsc/mouse/) :. MGI: J:133634
RUSSELL ES. 1949. A quantitative histological study of the pigment found in the coat-color mutants of the house mouse; interdependence among the variable granule attributes. Genetics 34(2):133-45. PubMed: 18117146 MGI: J:148461
Rachel RA; Nagashima K; O'Sullivan TN; Frost LS; Stefano FP; Marigo V; Boesze-Battaglia K. 2012. Melanoregulin, product of the dsu locus, links the BLOC-pathway and OA1 in organelle biogenesis. PLoS One 7(9):e42446. PubMed: 22984402 MGI: J:191882
Russell ES. 1949. A Quantitative Histological Study of the Pigment Found in the Coat-Color Mutants of the House Mouse. IV. the Nature of the Effects of Genic Substitution in Five Major Allelic Series. Genetics 34(2):146-66. PubMed: 17247308 MGI: J:12958
Russell ES. 1948. A Quantitative Histological Study of the Pigment Found in the Coat Color Mutants of the House Mouse. II. Estimates of the Total Volume of Pigment. Genetics 33(3):228-36. PubMed: 17247280 MGI: J:148462
Russell ES. 1946. A Quantitative Histological Study of the Pigment Found in the Coat-Color Mutants of the House Mouse. I. Variable Attributes of the Pigment Granules. Genetics 31(3):327-46. PubMed: 17247200 MGI: J:148463
Sweet HO. 1983. Dilute suppressor, a new suppressor gene in the house mouse. J Hered 74(4):305-6. PubMed: 6886377 MGI: J:7171
Yoshimura A; Fujii R; Watanabe Y; Okabe S; Fukui K; Takumi T. 2006. Myosin-Va facilitates the accumulation of mRNA/protein complex in dendritic spines. Curr Biol 16(23):2345-51. PubMed: 17141617 MGI: J:117928

Additional - Pde6b^rd1 related

Acosta ML; Fletcher EL; Azizoglu S; Foster LE; Farber DB; Kalloniatis M. 2005. Early markers of retinal degeneration in rd/rd mice. Mol Vis 11:717-28. PubMed: 16163270 MGI: J:103970
Aftab U; Jiang C; Tucker B; Kim JY; Klassen H; Miljan E; Sinden J; Young M. 2009. Growth kinetics and transplantation of human retinal progenitor cells. Exp Eye Res 89(3):301-10. PubMed: 19524569 MGI: J:151412
Ahuja S; Ahuja-Jensen P; Johnson LE; Caffe AR; Abrahamson M; Ekstrom PA; van Veen T. 2008. rd1 Mouse retina shows an imbalance in the activity of cysteine protease cathepsins and their endogenous inhibitor cystatin C. Invest Ophthalmol Vis Sci 49(3):1089-96. PubMed: 18326735 MGI: J:133024
Ahuja-Jensen P; Johnsen-Soriano S; Ahuja S; Bosch-Morell F; Sancho-Tello M; Romero FJ; Abrahamson M; van Veen T. 2007. Low glutathione peroxidase in rd1 mouse retina increases oxidative stress and proteases. Neuroreport 18(8):797-801. PubMed: 17471069 MGI: J:122802
Alavi MV; Bette S; Schimpf S; Schuettauf F; Schraermeyer U; Wehrl HF; Ruttiger L; Beck SC; Tonagel F; Pichler BJ; Knipper M; Peters T; Laufs J; Wissinger B. 2007. A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy. Brain 130(Pt 4):1029-42. PubMed: 17314202 MGI: J:154966
Allen AE; Brown TM; Lucas RJ. 2011. A distinct contribution of short-wavelength-sensitive cones to light-evoked activity in the mouse pretectal olivary nucleus. J Neurosci 31(46):16833-43. PubMed: 22090509 MGI: J:177906
Allen AE; Cameron MA; Brown TM; Vugler AA; Lucas RJ. 2010. Visual responses in mice lacking critical components of all known retinal phototransduction cascades. PLoS One 5(11):e15063. PubMed: 21124780 MGI: J:167121
Alvarez-Lopez C; Cernuda-Cernuda R; Alcorta E; Alvarez-Viejo M; Manuel Garcia-Fernandez J. 2004. Altered endogenous activation of CREB in the suprachiasmatic nucleus of mice with retinal degeneration. Brain Res 1024(1-2):137-45. PubMed: 15451375 MGI: J:92980
Alvarez-Lopez C; Cernuda-Cernuda R; Garcia-Fernandez JM. 2006. The mPer1 clock gene expression in the rd mouse suprachiasmatic nucleus is affected by the retinal degeneration. Brain Res 1087(1):134-41. PubMed: 16626665 MGI: J:109668
Alvarez-Lopez C; Cernuda-Cernuda R; Paniagua MA; Alvarez-Viejo M; Fernandez-Lopez A; Garcia-Fernandez JM. 2004. The transcription factor CREB is phosphorylated in neurons of the piriform cortex of blind mice in response to illumination of the retina. Neurosci Lett 357(3):223-6. PubMed: 15003290 MGI: J:121036
Arango-Gonzalez B; Trifunovic D; Sahaboglu A; Kranz K; Michalakis S; Farinelli P; Koch S; Koch F; Cottet S; Janssen-Bienhold U; Dedek K; Biel M; Zrenner E; Euler T; Ekstrom P; Ueffing M; Paquet-Durand F. 2014. Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration. PLoS One 9(11):e112142. PubMed: 25392995 MGI: J:225151
Ardayfio P; Moon J; Leung KK; Youn-Hwang D; Kim KS. 2008. Impaired learning and memory in Pitx3 deficient aphakia mice: A genetic model for striatum-dependent cognitive symptoms in Parkinson's disease. Neurobiol Dis :. PubMed: 18573342 MGI: J:136304
Ash J; McLeod DS; Lutty GA. 2005. Transgenic expression of leukemia inhibitory factor (LIF) blocks normal vascular development but not pathological neovascularization in the eye. Mol Vis 11:298-308. PubMed: 15889014 MGI: J:98579
Ash JA; Velazquez R; Kelley CM; Powers BE; Ginsberg SD; Mufson EJ; Strupp BJ. 2014. Maternal choline supplementation improves spatial mapping and increases basal forebrain cholinergic neuron number and size in aged Ts65Dn mice. Neurobiol Dis 70:32-42. PubMed: 24932939 MGI: J:218355
Atkinson CL; Feng J; Zhang DQ. 2013. Functional integrity and modification of retinal dopaminergic neurons in the rd1 mutant mouse: roles of melanopsin and GABA. J Neurophysiol 109(6):1589-99. PubMed: 23255724 MGI: J:238046
Audo I; Bujakowska K; Orhan E; Poloschek CM; Defoort-Dhellemmes S; Drumare I; Kohl S; Luu TD; Lecompte O; Zrenner E; Lancelot ME; Antonio A; Germain A; Michiels C; Audier C; Letexier M; Saraiva JP; Leroy BP; Munier FL; Mohand-Said S; Lorenz B; Friedburg C; Preising M; Kellner U; Renner AB; Moskova-Doumanova V; Berger W; Wissinger B; Hamel CP; Schorderet DF; De Baere E; Sharon D; Banin E; Jacobson SG; Bonneau D; Zanlonghi X; Le Meur G; Casteels I; Koenekoop R; Long VW; Meire F; Prescott K; de Ravel T; Simm. 2012. Whole-exome sequencing identifies mutations in GPR179 leading to autosomal-recessive complete congenital stationary night blindness. Am J Hum Genet 90(2):321-30. PubMed: 22325361 MGI: J:196741
Ayturk DG; Castrucci AM; Carr DE; Keller SR; Provencio I. 2015. Lack of Melanopsin Is Associated with Extreme Weight Loss in Mice upon Dietary Challenge. PLoS One 10(5):e0127031. PubMed: 26011287 MGI: J:237743
Azadi S; Paquet-Durand F; Medstrand P; van Veen T; Ekstrom PA. 2006. Up-regulation and increased phosphorylation of protein kinase C (PKC) delta, mu and theta in the degenerating rd1 mouse retina. Mol Cell Neurosci 31(4):759-73. PubMed: 16503160 MGI: J:108601
BRUCKNER R. 1951. [Slit-lamp microscopy and ophthalmoscopy in rat and mouse.] Doc Ophthalmol 5-6:452-554. PubMed: 14896883 MGI: J:25576
Ball SL; Powers PA; Shin HS; Morgans CW; Peachey NS; Gregg RG. 2002. Role of the beta(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer. Invest Ophthalmol Vis Sci 43(5):1595-603. PubMed: 11980879 MGI: J:80080
Barabas P; Liu A; Xing W; Chen CK; Tong Z; Watt CB; Jones BW; Bernstein PS; Krizaj D. 2013. Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration. Proc Natl Acad Sci U S A 110(13):5181-6. PubMed: 23479632 MGI: J:194246
Barber AC; Hippert C; Duran Y; West EL; Bainbridge JW; Warre-Cornish K; Luhmann UF; Lakowski J; Sowden JC; Ali RR; Pearson RA. 2013. Repair of the degenerate retina by photoreceptor transplantation. Proc Natl Acad Sci U S A 110(1):354-9. PubMed: 23248312 MGI: J:192521
Bhatti F; Ball G; Hobbs R; Linens A; Munzar S; Akram R; Barber AJ; Anderson M; Elliott M; Edwards M. 2015. Pulmonary surfactant protein a is expressed in mouse retina by Muller cells and impacts neovascularization in oxygen-induced retinopathy. Invest Ophthalmol Vis Sci 56(1):232-42. PubMed: 25406276 MGI: J:230990
Bi A; Cui J; Ma YP; Olshevskaya E; Pu M; Dizhoor AM; Pan ZH. 2006. Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration. Neuron 50(1):23-33. PubMed: 16600853 MGI: J:122947
Blanks JC; Bok D. 1977. An autoradiographic analysis of postnatal cell proliferation in the normal and degenerative mouse retina. J Comp Neurol 174(2):317-27. PubMed: 864040 MGI: J:5812
Borowska J; Trenholm S; Awatramani GB. 2011. An intrinsic neural oscillator in the degenerating mouse retina. J Neurosci 31(13):5000-12. PubMed: 21451038 MGI: J:171202
Bowes C; Danciger M; Kozak CA; Farber DB. 1989. Isolation of a candidate cDNA for the gene causing retinal degeneration in the rd mouse [published erratum appears in Proc Natl Acad Sci U S A 1990 Feb;87(4):1625] Proc Natl Acad Sci U S A 86(24):9722-6. PubMed: 2481314 MGI: J:10184
Bowes C; Li T; Danciger M; Baxter LC; Applebury ML; Farber DB. 1990. Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase [see comments] Nature 347(6294):677-80. PubMed: 1977087 MGI: J:10777
Bowes C; Li T; Frankel WN; Danciger M; Coffin JM; Applebury ML; Farber DB. 1993. Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase. Proc Natl Acad Sci U S A 90(7):2955-9. PubMed: 8385352 MGI: J:4366
Bramall AN; Szego MJ; Pacione LR; Chang I; Diez E; D'Orleans-Juste P; Stewart DJ; Hauswirth WW; Yanagisawa M; McInnes RR. 2013. Endothelin-2-mediated protection of mutant photoreceptors in inherited photoreceptor degeneration. PLoS One 8(2):e58023. PubMed: 23469133 MGI: J:198395
Brown TM; Gias C; Hatori M; Keding SR; Semo M; Coffey PJ; Gigg J; Piggins HD; Panda S; Lucas RJ. 2010. Melanopsin contributions to irradiance coding in the thalamo-cortical visual system. PLoS Biol 8(12):e1000558. PubMed: 21151887 MGI: J:170401
Brown TM; Tsujimura S; Allen AE; Wynne J; Bedford R; Vickery G; Vugler A; Lucas RJ. 2012. Melanopsin-based brightness discrimination in mice and humans. Curr Biol 22(12):1134-41. PubMed: 22633808 MGI: J:199509
Buhr ED; Van Gelder RN. 2014. Local photic entrainment of the retinal circadian oscillator in the absence of rods, cones, and melanopsin. Proc Natl Acad Sci U S A 111(23):8625-30. PubMed: 24843129 MGI: J:211359
Buhr ED; Yue WW; Ren X; Jiang Z; Liao HW; Mei X; Vemaraju S; Nguyen MT; Reed RR; Lang RA; Yau KW; Van Gelder RN. 2015. Neuropsin (OPN5)-mediated photoentrainment of local circadian oscillators in mammalian retina and cornea. Proc Natl Acad Sci U S A 112(42):13093-8. PubMed: 26392540 MGI: J:227078
Bumsted KM; Rizzolo LJ; Barnstable CJ. 2001. Defects in the MITF(mi/mi) apical surface are associated with a failure of outer segment elongation. Exp Eye Res 73(3):383-92. PubMed: 11520113 MGI: J:115620
Busskamp V; Duebel J; Balya D; Fradot M; Viney TJ; Siegert S; Groner AC; Cabuy E; Forster V; Seeliger M; Biel M; Humphries P; Paques M; Mohand-Said S; Trono D; Deisseroth K; Sahel JA; Picaud S; Roska B. 2010. Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa. Science 329(5990):413-7. PubMed: 20576849 MGI: J:162017
Cai R; Xue W; Liu S; Petersen RB; Huang K; Zheng L. 2015. Overexpression of glyceraldehyde 3-phosphate dehydrogenase prevents neurovascular degeneration after retinal injury. FASEB J 29(7):2749-58. PubMed: 25805836 MGI: J:225470
Caley DW; Johnson C; Liebelt RA. 1972. The postnatal development of the retina in the normal and rodless CBA mouse: a light and electron microscopic study. Am J Anat 133(2):179-212. PubMed: 5009246 MGI: J:5250
Cameron MA; Pozdeyev N; Vugler AA; Cooper H; Iuvone PM; Lucas RJ. 2009. Light regulation of retinal dopamine that is independent of melanopsin phototransduction. Eur J Neurosci 29(4):761-7. PubMed: 19200071 MGI: J:146469
Carter-Dawson LD; LaVail MM; Sidman RL. 1978. Differential effect of the rd mutation on rods and cones in the mouse retina. Invest Ophthalmol Vis Sci 17(6):489-98. PubMed: 659071 MGI: J:5988
Cayouette M; Gravel C. 1997. Adenovirus-mediated gene transfer of ciliary neurotrophic factor can prevent photoreceptor degeneration in the retinal degeneration (rd) mouse. Hum Gene Ther 8(4):423-30. PubMed: 9054517 MGI: J:39262
Cayouette M; Smith SB; Becerra SP; Gravel C. 1999. Pigment epithelium-derived factor delays the death of photoreceptors in mouse models of inherited retinal degenerations. Neurobiol Dis 6(6):523-32. PubMed: 10600408 MGI: J:59343
Chang B; Hawes NL; Hurd RE; Davisson MT; Nusinowitz S; Heckenlively JR. 2002. Retinal degeneration mutants in the mouse. Vision Res 42(4):517-25. PubMed: 11853768 MGI: J:75095
Chang B; Hawes NL; Hurd RE; Wang J; Howell D; Davisson MT; Roderick TH; Nusinowitz S; Heckenlively JR. 2005. Mouse models of ocular diseases. Vis Neurosci 22(5):587-93. PubMed: 16332269 MGI: J:156373
Chang B; Hurd R; Wang J; Nishina P. 2013. Survey of common eye diseases in laboratory mouse strains. Invest Ophthalmol Vis Sci 54(7):4974-81. PubMed: 23800770 MGI: J:198916
Charbel Issa P; Singh MS; Lipinski DM; Chong NV; Delori FC; Barnard AR; MacLaren RE. 2012. Optimization of in vivo confocal autofluorescence imaging of the ocular fundus in mice and its application to models of human retinal degeneration. Invest Ophthalmol Vis Sci 53(2):1066-75. PubMed: 22169101 MGI: J:191520
Chen B; Cepko CL. 2009. HDAC4 regulates neuronal survival in normal and diseased retinas. Science 323(5911):256-9. PubMed: 19131628 MGI: J:143166
Chen Q; Khoury M; Chen J. 2009. Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice. Proc Natl Acad Sci U S A :. PubMed: 19966223 MGI: J:155817
Chua J; Nivison-Smith L; Fletcher EL; Trenholm S; Awatramani GB; Kalloniatis M. 2013. Early remodeling of Muller cells in the rd/rd mouse model of retinal dystrophy. J Comp Neurol 521(11):2439-53. PubMed: 23348616 MGI: J:200732
Cohen AI; Blazynski C. 1990. Dopamine and its agonists reduce a light-sensitive pool of cyclic AMP in mouse photoreceptors. Vis Neurosci 4(1):43-52. PubMed: 1702315 MGI: J:78184
Comitato A; Sanges D; Rossi A; Humphries MM; Marigo V. 2014. Activation of Bax in three models of retinitis pigmentosa. Invest Ophthalmol Vis Sci 55(6):3555-62. PubMed: 24825107 MGI: J:230024
Cornett A; Sucic JF; Hillsburg D; Cyr L; Johnson C; Polanco A; Figuereo J; Cabine K; Russo N; Sturtevant A; Jarvinen MK. 2011. Altered glial gene expression, density, and architecture in the visual cortex upon retinal degeneration. Brain Res 1422:46-56. PubMed: 21983206 MGI: J:179028
Danciger M; Bowes C; Kozak CA; LaVail MM; Farber DB. 1990. Fine mapping of a putative rd cDNA and its co-segregation with rd expression. Invest Ophthalmol Vis Sci 31(8):1427-32. PubMed: 1974892 MGI: J:10689
Daniels DM; Stoddart CW; Martin-Iverson MT; Lai CM; Redmond TM; Rakoczy PE. 2003. Entrainment of circadian rhythm to a photoperiod reversal shows retinal dystrophy in RPE65(-/-) mice. Physiol Behav 79(4-5):701-11. PubMed: 12954412 MGI: J:96439
Davies VJ; Powell KA; White KE; Yip W; Hogan V; Hollins AJ; Davies JR; Piechota M; Brownstein DG; Moat SJ; Nichols PP; Wride MA; Boulton ME; Votruba M. 2008. A missense mutation in the murine Opa3 gene models human Costeff syndrome. Brain 131(Pt 2):368-80. PubMed: 18222992 MGI: J:181670
Davis KE; Eleftheriou CG; Allen AE; Procyk CA; Lucas RJ. 2015. Melanopsin-derived visual responses under light adapted conditions in the mouse dLGN. PLoS One 10(3):e0123424. PubMed: 25822371 MGI: J:233435
Davis RJ; Tosi J; Janisch KM; Kasanuki JM; Wang NK; Kong J; Tsui I; Cilluffo M; Woodruff ML; Fain GL; Lin CS; Tsang SH. 2008. Functional rescue of degenerating photoreceptors in mice homozygous for a hypomorphic cGMP phosphodiesterase 6 b allele (Pde6bH620Q). Invest Ophthalmol Vis Sci 49(11):5067-76. PubMed: 18658088 MGI: J:141984
Del Rio P; Irmler M; Arango-Gonzalez B; Favor J; Bobe C; Bartsch U; Vecino E; Beckers J; Hauck SM; Ueffing M. 2011. GDNF-induced osteopontin from Muller glial cells promotes photoreceptor survival in the Pde6b(rd1) mouse model of retinal degeneration. Glia 59(5):821-32. PubMed: 21360756 MGI: J:169746
Delyfer MN; Forster V; Neveux N; Picaud S; Leveillard T; Sahel JA. 2005. Evidence for glutamate-mediated excitotoxic mechanisms during photoreceptor degeneration in the rd1 mouse retina. Mol Vis 11:688-96. PubMed: 16163266 MGI: J:103968
Demos C; Bandyopadhyay M; Rohrer B. 2008. Identification of candidate genes for human retinal degeneration loci using differentially expressed genes from mouse photoreceptor dystrophy models. Mol Vis 14:1639-49. PubMed: 18776951 MGI: J:140115
Doonan F; Donovan M; Cotter TG. 2003. Caspase-independent photoreceptor apoptosis in mouse models of retinal degeneration. J Neurosci 23(13):5723-31. PubMed: 12843276 MGI: J:84389
Drager UC; Hubel DH. 1978. Studies of visual function and its decay in mice with hereditary retinal degeneration. J Comp Neurol 180(1):85-114. PubMed: 649791 MGI: J:5980
Du Y; Davisson MT; Kafadar K; Gardiner K. 2006. A-to-I pre-mRNA editing of the serotonin 2C receptor: comparisons among inbred mouse strains. Gene 382:39-46. PubMed: 16904273 MGI: J:115050
Ekstrom P; Sanyal S; Narfstrom K; Chader GJ; van Veen T. 1988. Accumulation of glial fibrillary acidic protein in Muller radial glia during retinal degeneration. Invest Ophthalmol Vis Sci 29(9):1363-71. PubMed: 3417421 MGI: J:27850
El Shamieh S; Neuille M; Terray A; Orhan E; Condroyer C; Demontant V; Michiels C; Antonio A; Boyard F; Lancelot ME; Letexier M; Saraiva JP; Leveillard T; Mohand-Said S; Goureau O; Sahel JA; Zeitz C; Audo I. 2014. Whole-exome sequencing identifies KIZ as a ciliary gene associated with autosomal-recessive rod-cone dystrophy. Am J Hum Genet 94(4):625-33. PubMed: 24680887 MGI: J:227870
Feng BS; He SH; Zheng PY; Wu L; Yang PC. 2007. Mast cells play a crucial role in Staphylococcus aureus peptidoglycan-induced diarrhea. Am J Pathol 171(2):537-47. PubMed: 17600127 MGI: J:123928
Flanigan TJ; Xue Y; Kishan Rao S; Dhanushkodi A; McDonald MP. 2014. Abnormal vibrissa-related behavior and loss of barrel field inhibitory neurons in 5xFAD transgenics. Genes Brain Behav 13(5):488-500. PubMed: 24655396 MGI: J:223699
Fletcher RT; Sanyal S; Krishna G; Aguirre G; Chader GJ. 1986. Genetic expression of cyclic GMP phosphodiesterase activity defines abnormal photoreceptor differentiation in neurological mutants of inherited retinal degeneration. J Neurochem 46(4):1240-5. PubMed: 3005510 MGI: J:12044
Foster RG; Argamaso S; Coleman S; Colwell CS; Lederman A; Provencio I. 1993. Photoreceptors regulating circadian behavior: a mouse model. J Biol Rhythms 8 Suppl:S17-23. PubMed: 8274758 MGI: J:17940
Foster RG; Provencio I; Hudson D; Fiske S; De Grip W; Menaker M. 1991. Circadian photoreception in the retinally degenerate mouse (rd/rd). J Comp Physiol [A] 169(1):39-50. PubMed: 1941717 MGI: J:83743
Frasson M; Picaud S; Leveillard T; Simonutti M; Mohand-Said S; Dreyfus H; Hicks D; Sabel J. 1999. Glial cell line-derived neurotrophic factor induces histologic and functional protection of rod photoreceptors in the rd/rd mouse. Invest Ophthalmol Vis Sci 40(11):2724-34. PubMed: 10509671 MGI: J:57866
Frasson M; Sahel JA; Fabre M; Simonutti M; Dreyfus H; Picaud S. 1999. Retinitis pigmentosa: rod photoreceptor rescue by a calcium-channel blocker in the rd mouse. Nat Med 5(10):1183-7. PubMed: 10502823 MGI: J:57986
Gao H; Hollyfield JG. 1995. Basic fibroblast growth factor in retinal development: differential levels of bFGF expression and content in normal and retinal degeneration (rd) mutant mice. Dev Biol 169(1):168-184. PubMed: 7750636 MGI: J:25273
Garcia-Fernandez JM; Jimenez AJ; Foster RG. 1995. The persistence of cone photoreceptors within the dorsal retina of aged retinally degenerate mice (rd/rd): implications for circadian organization. Neurosci Lett 187(1):33-6. PubMed: 7617296 MGI: J:25157
Gaub BM; Berry MH; Holt AE; Reiner A; Kienzler MA; Dolgova N; Nikonov S; Aguirre GD; Beltran WA; Flannery JG; Isacoff EY. 2014. Restoration of visual function by expression of a light-gated mammalian ion channel in retinal ganglion cells or ON-bipolar cells. Proc Natl Acad Sci U S A 111(51):E5574-83. PubMed: 25489083 MGI: J:216941
Gimenez E; Montoliu L. 2001. A simple polymerase chain reaction assay for genotyping the retinal degeneration mutation (Pdeb(rd1)) in FVB/N-derived transgenic mice. Lab Anim 35(2):153-6. PubMed: 11315164 MGI: J:69558
Goel M; Dhingra NK. 2012. Muller glia express rhodopsin in a mouse model of inherited retinal degeneration. Neuroscience 225:152-61. PubMed: 22967839 MGI: J:192477
Golub MS; Germann SL; Mercer M; Gordon MN; Morgan DG; Mayer LP; Hoyer PB. 2008. Behavioral consequences of ovarian atrophy and estrogen replacement in the APPswe mouse. Neurobiol Aging 29(10):1512-23. PubMed: 17451844 MGI: J:140912
Gouras P; Du J; Kjeldbye H; Kwun R; Lopez R; Zack DJ. 1991. Transplanted photoreceptors identified in dystrophic mouse retina by a transgenic reporter gene. Invest Ophthalmol Vis Sci 32(13):3167-74. PubMed: 1748547 MGI: J:607
Gouras P; Du J; Kjeldbye H; Yamamoto S; Zack DJ. 1994. Long-term photoreceptor transplants in dystrophic and normal mouse retina. Invest Ophthalmol Vis Sci 35(8):3145-53. PubMed: 8045709 MGI: J:20769
Grafstein B; Murray M; Ingoglia NA. 1972. Protein synthesis and axonal transport in retinal ganglion cells of mice lacking visual receptors. Brain Res 44(1):37-48. PubMed: 4115728 MGI: J:5292
Graham DR; Overbeek PA; Ash JD. 2005. Leukemia inhibitory factor blocks expression of crx and nrl transcription factors to inhibit photoreceptor differentiation. Invest Ophthalmol Vis Sci 46(7):2601-10. PubMed: 15980254 MGI: J:99409
Greferath U; Goh HC; Chua PY; Astrand E; O'Brien EE; Fletcher EL; Murphy M. 2009. Mapping retinal degeneration and loss-of-function in Rd-FTL mice. Invest Ophthalmol Vis Sci 50(12):5955-64. PubMed: 19661224 MGI: J:158255
Grimm C; Wenzel A; Stanescu D; Samardzija M; Hotop S; Groszer M; Naash M; Gassmann M; Reme C. 2004. Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration. J Neurosci 24(25):5651-8. PubMed: 15215287 MGI: J:133235
Hackam AS; Strom R; Liu D; Qian J; Wang C; Otteson D; Gunatilaka T; Farkas RH; Chowers I; Kageyama M; Leveillard T; Sahel JA; Campochiaro PA; Parmigiani G; Zack DJ. 2004. Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse. Invest Ophthalmol Vis Sci 45(9):2929-42. PubMed: 15326104 MGI: J:92921
Hafezi F; Abegg M; Grimm C; Wenzel A; Munz K; Sturmer J; Farber DB; Reme CE. 1998. Retinal degeneration in the rd mouse in the absence of c-fos. Invest Ophthalmol Vis Sci 39(12):2239-44. PubMed: 9804131 MGI: J:112088
Hanno Y; Nakahira M; Jishage K; Noda T; Yoshihara Y. 2003. Tracking mouse visual pathways with WGA transgene. Eur J Neurosci 18(10):2910-4. PubMed: 14656342 MGI: J:128266
Hart AW; McKie L; Morgan JE; Gautier P; West K; Jackson IJ; Cross SH. 2005. Genotype-phenotype correlation of mouse pde6b mutations. Invest Ophthalmol Vis Sci 46(9):3443-50. PubMed: 16123450 MGI: J:101336
Hatori M; Gill S; Mure LS; Goulding M; O'Leary DD; Panda S. 2014. Lhx1 maintains synchrony among circadian oscillator neurons of the SCN. Elife 3:e03357. PubMed: 25035422 MGI: J:228603
Hatori M; Le H; Vollmers C; Keding SR; Tanaka N; Schmedt C; Jegla T; Panda S. 2008. Inducible ablation of melanopsin-expressing retinal ganglion cells reveals their central role in non-image forming visual responses. PLoS One 3(6):e2451. PubMed: 18545654 MGI: J:137151
Hawes NL; Smith RS; Chang B; Davisson M; Heckenlively JR; John SW. 1999. Mouse fundus photography and angiography: a catalogue of normal and mutant phenotypes. Mol Vis 5:22. PubMed: 10493779 MGI: J:59481
Heckenlively JR; Chang B; Erway LC; Peng C; Hawes NL; Hageman GS; Roderick TH. 1995. Mouse model for Usher syndrome: linkage mapping suggests homology to Usher type I reported at human chromosome 11p15. Proc Natl Acad Sci U S A 92(24):11100-4. PubMed: 7479945 MGI: J:121993
Heynen SR; Tanimoto N; Joly S; Seeliger MW; Samardzija M; Grimm C. 2011. Retinal degeneration modulates intracellular localization of CDC42 in photoreceptors. Mol Vis 17:2934-46. PubMed: 22128240 MGI: J:179662
Hippert C; Graca AB; Barber AC; West EL; Smith AJ; Ali RR; Pearson RA. 2015. Muller glia activation in response to inherited retinal degeneration is highly varied and disease-specific. PLoS One 10(3):e0120415. PubMed: 25793273 MGI: J:233438
Holt R; Brown L; Broadgate S; Butler R; Jagannath A; Downes S; Peirson S; Halford S. 2015. Identification of rod- and cone-specific expression signatures to identify candidate genes for retinal disease. Exp Eye Res 132:161-73. PubMed: 25579607 MGI: J:230269
Hopp RM; Ransom N; Hilsenbeck SG; Papermaster DS; Windle JJ. 1998. Apoptosis in the murine rd1 retinal degeneration is predominantly p53-independent. Mol Vis 4:5. PubMed: 9485488 MGI: J:47520
Horev G; Benjamini Y; Sakov A; Golani I. 2007. Estimating wall guidance and attraction in mouse free locomotor behavior. Genes Brain Behav 6(1):30-41. PubMed: 17233639 MGI: J:132656
Hsiao FC; Liao YH; Tsai LL. 2013. Differential effects of retinal degeneration on sleep and wakefulness responses to short light-dark cycles in albino mice. Neuroscience 248C:459-468. PubMed: 23811394 MGI: J:207054
Huber G; Beck SC; Grimm C; Sahaboglu-Tekgoz A; Paquet-Durand F; Wenzel A; Humphries P; Redmond TM; Seeliger MW; Fischer MD. 2009. Spectral domain optical coherence tomography in mouse models of retinal degeneration. Invest Ophthalmol Vis Sci 50(12):5888-95. PubMed: 19661229 MGI: J:158254
Huerta JJ; Llamosas MM; Cernuda-Cernuda R; Garcia-Fernandez JM. 1999. Spatio-temporal analysis of light-induced Fos expression in the retina of rd mutant mice. Brain Res 834(1-2):122-7. PubMed: 10407100 MGI: J:56973
Huerta JJ; Llamosas MM; Cernuda-Cernuda R; Garcia-Fernandez JM. 1997. Fos expression in the retina of rd/rd mice during the light/dark cycle. Neurosci Lett 232(3):143-6. PubMed: 9310300 MGI: J:43873
Hughes S; Jagannath A; Hickey D; Gatti S; Wood M; Peirson SN; Foster RG; Hankins MW. 2015. Using siRNA to define functional interactions between melanopsin and multiple G Protein partners. Cell Mol Life Sci 72(1):165-79. PubMed: 24958088 MGI: J:232057
Hughes S; Pothecary CA; Jagannath A; Foster RG; Hankins MW; Peirson SN. 2012. Profound defects in pupillary responses to light in TRPM-channel null mice: a role for TRPM channels in non-image-forming photoreception. Eur J Neurosci 35(1):34-43. PubMed: 22211741 MGI: J:184336
Hussain AA; Willmott NJ; Voaden MJ. 1992. Cyclic GMP, calcium and photoreceptor sensitivity in mice heterozygous for the rod dysplasia gene designated rd. Vision Res 32(1):29-36. PubMed: 1323896 MGI: J:611
Hwang DY; Fleming SM; Ardayfio P; Moran-Gates T; Kim H; Tarazi FI; Chesselet MF; Kim KS. 2005. 3,4-dihydroxyphenylalanine reverses the motor deficits in Pitx3-deficient aphakia mice: behavioral characterization of a novel genetic model of Parkinson's disease. J Neurosci 25(8):2132-7. PubMed: 15728853 MGI: J:98209
Ionita MA; Pittler SJ. 2007. Focus on molecules: rod cGMP phosphodiesterase type 6. Exp Eye Res 84(1):1-2. PubMed: 16563379 MGI: J:123170
Ivanova E; Yee CW; Sagdullaev BT. 2016. Disruption in dopaminergic innervation during photoreceptor degeneration. J Comp Neurol 524(6):1208-21. PubMed: 26356010 MGI: J:231114
Ivanova E; Yee CW; Sagdullaev BT. 2015. Increased phosphorylation of Cx36 gap junctions in the AII amacrine cells of RD retina. Front Cell Neurosci 9:390. PubMed: 26483638 MGI: J:239860
Janus C; Flores AY; Xu G; Borchelt DR. 2015. Behavioral abnormalities in APPSwe/PS1dE9 mouse model of AD-like pathology: comparative analysis across multiple behavioral domains. Neurobiol Aging 36(9):2519-32. PubMed: 26089165 MGI: J:226285
Ji X; Liu Y; Hurd R; Wang J; Fitzmaurice B; Nishina PM; Chang B. 2016. Retinal Pigment Epithelium Atrophy 1 (rpea1): A New Mouse Model With Retinal Detachment Caused by a Disruption of Protein Kinase C, theta. Invest Ophthalmol Vis Sci 57(3):877-88. PubMed: 26978024 MGI: J:237977
Jia L; Oh EC; Ng L; Srinivas M; Brooks M; Swaroop A; Forrest D. 2009. Retinoid-related orphan nuclear receptor RORbeta is an early-acting factor in rod photoreceptor development. Proc Natl Acad Sci U S A 106(41):17534-9. PubMed: 19805139 MGI: J:153683
Johnson LE; van Veen T; Ekstrom PA. 2005. Differential Akt activation in the photoreceptors of normal and rd1 mice. Cell Tissue Res 320(2):213-22. PubMed: 15789220 MGI: J:105103
Jomary C; Cullen J; Jones SE. 2006. Inactivation of the Akt survival pathway during photoreceptor apoptosis in the retinal degeneration mouse. Invest Ophthalmol Vis Sci 47(4):1620-9. PubMed: 16565401 MGI: J:108445
Jomary C; Thomas M; Grist J; Milbrandt J; Neal MJ; Jones SE. 1999. Expression patterns of neurturin and its receptor components in developing and degenerative mouse retina. Invest Ophthalmol Vis Sci 40(3):568-74. PubMed: 10067959 MGI: J:53298
Jones BW; Watt CB; Frederick JM; Baehr W; Chen CK; Levine EM; Milam AH; Lavail MM; Marc RE. 2003. Retinal remodeling triggered by photoreceptor degenerations. J Comp Neurol 464(1):1-16. PubMed: 12866125 MGI: J:84675
Jones SE; Jomary C; Grist J; Stewart HJ; Neal MJ. 2000. Identification by array screening of altered nm23-M2/PuF mRNA expression in mouse retinal degeneration. Mol Cell Biol Res Commun 4(1):20-5. PubMed: 11152623 MGI: J:66982
Jones SE; Jomary C; Grist J; Thomas MR; Neal MJ. 1998. Expression of Pax-6 mRNA in the retinal degeneration (rd) mouse. Biochem Biophys Res Commun 252(1):236-40. PubMed: 9813176 MGI: J:50978
Jones SE; Jomary C; Grist J; Thomas MR; Neal MJ. 1998. Expression of alphaB-crystallin in a mouse model of inherited retinal degeneration. Neuroreport 9(18):4161-5. PubMed: 9926867 MGI: J:52955
Joseph RM; Li T. 1996. Overexpression of Bcl-2 or Bcl-XL transgenes and photoreceptor degeneration. Invest Ophthalmol Vis Sci 37(12):2434-46. PubMed: 8933760 MGI: J:37285
Kahle M; Horsch M; Fridrich B; Seelig A; Schultheiss J; Leonhardt J; Irmler M; Beckers J; Rathkolb B; Wolf E; Franke N; Gailus-Durner V; Fuchs H; de Angelis MH; Neschen S. 2013. Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis. Mol Metab 2(4):435-46. PubMed: 24327959 MGI: J:220415
Kanan Y; Hoffhines A; Rauhauser A; Murray A; Al-Ubaidi MR. 2009. Protein tyrosine-O-sulfation in the retina. Exp Eye Res 89(4):559-67. PubMed: 19523945 MGI: J:154498
Kaneko H; Nishiguchi KM; Nakamura M; Kachi S; Terasaki H. 2008. Retardation of photoreceptor degeneration in the detached retina of rd1 mouse. Invest Ophthalmol Vis Sci 49(2):781-7. PubMed: 18235028 MGI: J:132586
Karasawa K; Tanaka A; Jung K; Matsuda A; Okamoto N; Oida K; Ebihara N; Ohmori K; Matsuda H. 2011. Retinal degeneration and rd1 mutation in NC/Tnd mice-a human atopic dermatitis model. Curr Eye Res 36(4):350-7. PubMed: 21275519 MGI: J:179794
Katti C; Butler R; Sekaran S. 2013. Diurnal and circadian regulation of connexin 36 transcript and protein in the mammalian retina. Invest Ophthalmol Vis Sci 54(1):821-9. PubMed: 23307963 MGI: J:214563
Keady BT; Le YZ; Pazour GJ. 2011. IFT20 is required for opsin trafficking and photoreceptor outer segment development. Mol Biol Cell 22(7):921-30. PubMed: 21307337 MGI: J:183002
Keeler C. 1966. Retinal degeneration in the mouse is rodless retina. J Hered 57(2):47-50. PubMed: 5916892 MGI: J:5007
Keeler CE. 1926. On the Occurrence in the House Mouse of Mendelizing Structural Defect of the Retina Producing Blindness. Proc Natl Acad Sci U S A 12(4):255-8. PubMed: 16576989 MGI: J:153354
Keeler CE. 1924. The inheritance of a retinal abnormality in white mice Proc Natl Acad Sci U S A 10(7):329-33. PubMed: 16576828 MGI: J:24999
Keeler CE; Sutcliffe E; Chaffee EL. 1928. Normal and 'Rodless' Retinae of the House Mouse with Respect to the Electromotive Force Generated through Stimulation by Light. Proc Natl Acad Sci U S A 14(6):477-84. PubMed: 16577134 MGI: J:153353
Kida E; Rabe A; Walus M; Albertini G; Golabek AA. 2013. Long-term running alleviates some behavioral and molecular abnormalities in Down syndrome mouse model Ts65Dn. Exp Neurol 240:178-89. PubMed: 23201095 MGI: J:196979
Kirschman LT; Kolandaivelu S; Frederick JM; Dang L; Goldberg AF; Baehr W; Ramamurthy V. 2010. The Leber congenital amaurosis protein, AIPL1, is needed for the viability and functioning of cone photoreceptor cells. Hum Mol Genet 19(6):1076-87. PubMed: 20042464 MGI: J:157652
Klein SL; Kriegsfeld LJ; Hairston JE; Rau V; Nelson RJ; Yarowsky PJ. 1996. Characterization of sensorimotor performance, reproductive and aggressive behaviors in segmental trisomic 16 (Ts65Dn) mice. Physiol Behav 60(4):1159-64. PubMed: 8884947 MGI: J:174274
Kokkinopoulos I; Pearson RA; Macneil A; Dhomen NS; Maclaren RE; Ali RR; Sowden JC. 2008. Isolation and characterisation of neural progenitor cells from the adult Chx10(orJ/orJ) central neural retina. Mol Cell Neurosci 38(3):359-73. PubMed: 18514541 MGI: J:137047
Kolandaivelu S; Chang B; Ramamurthy V. 2011. Rod Phosphodiesterase-6 (PDE6) Catalytic Subunits Restore Cone Function in a Mouse Model Lacking Cone PDE6 Catalytic Subunit. J Biol Chem 286(38):33252-9. PubMed: 21799013 MGI: J:176734
Kolandaivelu S; Huang J; Hurley JB; Ramamurthy V. 2009. AIPL1, a protein associated with childhood blindness, interacts with alpha-subunit of rod phosphodiesterase (PDE6) and is essential for its proper assembly. J Biol Chem 284(45):30853-61. PubMed: 19758987 MGI: J:156330
Komeima K; Rogers BS; Lu L; Campochiaro PA. 2006. Antioxidants reduce cone cell death in a model of retinitis pigmentosa. Proc Natl Acad Sci U S A 103(30):11300-5. PubMed: 16849425 MGI: J:111826
Komeima K; Usui S; Shen J; Rogers BS; Campochiaro PA. 2008. Blockade of neuronal nitric oxide synthase reduces cone cell death in a model of retinitis pigmentosa. Free Radic Biol Med 45(6):905-12. PubMed: 18634866 MGI: J:142007
Kooragayala K; Gotoh N; Cogliati T; Nellissery J; Kaden TR; French S; Balaban R; Li W; Covian R; Swaroop A. 2015. Quantification of Oxygen Consumption in Retina Ex Vivo Demonstrates Limited Reserve Capacity of Photoreceptor Mitochondria. Invest Ophthalmol Vis Sci 56(13):8428-36. PubMed: 26747773 MGI: J:231018
Koso H; Tsuhako A; Lai CY; Baba Y; Otsu M; Ueno K; Nagasaki M; Suzuki Y; Watanabe S. 2016. Conditional rod photoreceptor ablation reveals Sall1 as a microglial marker and regulator of microglial morphology in the retina. Glia 64(11):2005-24. PubMed: 27459098 MGI: J:235625
Kranz K; Paquet-Durand F; Weiler R; Janssen-Bienhold U; Dedek K. 2013. Testing for a gap junction-mediated bystander effect in retinitis pigmentosa: secondary cone death is not altered by deletion of connexin36 from cones. PLoS One 8(2):e57163. PubMed: 23468924 MGI: J:199394
Kucharska J; Del Rio P; Arango-Gonzalez B; Gorza M; Feuchtinger A; Hauck SM; Ueffing M. 2014. Cyr61 activates retinal cells and prolongs photoreceptor survival in rd1 mouse model of retinitis pigmentosa. J Neurochem 130(2):227-40. PubMed: 24593181 MGI: J:213667
Kuenzi F; Rosahl TW; Morton RA; Fitzjohn SM; Collingridge GL; Seabrook GR. 2003. Hippocampal synaptic plasticity in mice carrying the rd mutation in the gene encoding cGMP phosphodiesterase type 6 (PDE6). Brain Res 967(1-2):144-51. PubMed: 12650975 MGI: J:82830
Kulkarni M; Trifunovic D; Schubert T; Euler T; Paquet-Durand F. 2016. Calcium dynamics change in degenerating cone photoreceptors. Hum Mol Genet 25(17):3729-3740. PubMed: 27402880 MGI: J:237860
LaVail MM; Matthes MT; Yasumura D; Steinberg RH. 1997. Variability in rate of cone degeneration in the retinal degeneration (rd/rd) mouse. Exp Eye Res 65(1):45-50. PubMed: 9237863 MGI: J:42223
LaVail MM; Mullen RJ. 1976. Role of the pigment epithelium in inherited retinal degeneration analyzed with experimental mouse chimeras. Exp Eye Res 23(2):227-45. PubMed: 976367 MGI: J:5708
LaVail MW; Yasumura D; Matthes MT; Lau-Villacorta C; Unoki K; Sung CH; Steinberg RH. 1998. Protection of mouse photoreceptors by survival factors in retinal degenerations. Invest Ophthalmol Vis Sci 39(3):592-602. PubMed: 9501871 MGI: J:46230
Lahdenranta J; Pasqualini R; Schlingemann RO; Hagedorn M; Stallcup WB; Bucana CD; Sidman RL; Arap W. 2001. An anti-angiogenic state in mice and humans with retinal photoreceptor cell degeneration. Proc Natl Acad Sci U S A 98(18):10368-73. PubMed: 11526242 MGI: J:126744
Langmann T; Di Gioia SA; Rau I; Stohr H; Maksimovic NS; Corbo JC; Renner AB; Zrenner E; Kumaramanickavel G; Karlstetter M; Arsenijevic Y; Weber BH; Gal A; Rivolta C. 2010. Nonsense mutations in FAM161A cause RP28-associated recessive retinitis pigmentosa. Am J Hum Genet 87(3):376-81. PubMed: 20705278 MGI: J:169189
Lavail MM; Nishikawa S; Duncan JL; Yang H; Matthes MT; Yasumura D; Vollrath D; Overbeek PA; Ash JD; Robinson ML. 2008. Sustained delivery of NT-3 from lens fiber cells in transgenic mice reveals specificity of neuroprotection in retinal degenerations. J Comp Neurol 511(6):724-35. PubMed: 18925574 MGI: J:176641
Lin B; Koizumi A; Tanaka N; Panda S; Masland RH. 2008. Restoration of visual function in retinal degeneration mice by ectopic expression of melanopsin. Proc Natl Acad Sci U S A 105(41):16009-14. PubMed: 18836071 MGI: J:141434
Lin B; Masland RH; Strettoi E. 2009. Remodeling of cone photoreceptor cells after rod degeneration in rd mice. Exp Eye Res 88(3):589-99. PubMed: 19087876 MGI: J:146569
Lin B; Peng EB. 2013. Retinal ganglion cells are resistant to photoreceptor loss in retinal degeneration. PLoS One 8(6):e68084. PubMed: 23840814 MGI: J:204325
Liu SH; Gottsch JD; Vinores SA; Derevjanik NL; McLeod DS; Lutty GA. 2001. EMAP cytokine expression in developing retinas of normal and retinal degeneration (rd) mutant mice. J Neuroimmunol 114(1-2):28-34. PubMed: 11240012 MGI: J:102963
Lohr HR; Kuntchithapautham K; Sharma AK; Rohrer B. 2006. Multiple, parallel cellular suicide mechanisms participate in photoreceptor cell death. Exp Eye Res 83(2):380-9. PubMed: 16626700 MGI: J:116326
Louros SR; Hooks BM; Litvina L; Carvalho AL; Chen C. 2014. A role for stargazin in experience-dependent plasticity. Cell Rep 7(5):1614-25. PubMed: 24882000 MGI: J:211786
Lu B; Coffey P; Lund R. 2004. Increased c-fos-like immunoreactivity in the superior colliculus and lateral geniculate nucleus of the rd mouse. Brain Res 1025(1-2):220-5. PubMed: 15464763 MGI: J:107774
Lucas RJ; Freedman MS; Munoz M; Garcia-Fernandez JM; Foster RG. 1999. Regulation of the mammalian pineal by non-rod, non-cone, ocular photoreceptors. Science 284(5413):505-7. PubMed: 10205062 MGI: J:128478
Lupi D; Oster H; Thompson S; Foster RG. 2008. The acute light-induction of sleep is mediated by OPN4-based photoreception. Nat Neurosci :. PubMed: 18711396 MGI: J:141041
Lupi D; Semo M; Foster RG. 2012. Impact of age and retinal degeneration on the light input to circadian brain structures. Neurobiol Aging 33(2):383-92. PubMed: 20409612 MGI: J:188243
Majumder A; Pahlberg J; Muradov H; Boyd KK; Sampath AP; Artemyev NO. 2015. Exchange of Cone for Rod Phosphodiesterase 6 Catalytic Subunits in Rod Photoreceptors Mimics in Part Features of Light Adaptation. J Neurosci 35(24):9225-35. PubMed: 26085644 MGI: J:222549
Marc RE; Jones BW; Anderson JR; Kinard K; Marshak DW; Wilson JH; Wensel T; Lucas RJ. 2007. Neural reprogramming in retinal degeneration. Invest Ophthalmol Vis Sci 48(7):3364-71. PubMed: 17591910 MGI: J:123271
Margolis DJ; Gartland AJ; Singer JH; Detwiler PB. 2014. Network oscillations drive correlated spiking of ON and OFF ganglion cells in the rd1 mouse model of retinal degeneration. PLoS One 9(1):e86253. PubMed: 24489706 MGI: J:212697
Masana MI; Sumaya IC; Becker-Andre M; Dubocovich ML. 2007. Behavioral characterization and modulation of circadian rhythms by light and melatonin in C3H/HeN mice homozygous for the RORbeta knockout. Am J Physiol Regul Integr Comp Physiol 292(6):R2357-67. PubMed: 17303680 MGI: J:121989
Matynia A; Parikh S; Chen B; Kim P; McNeill DS; Nusinowitz S; Evans C; Gorin MB. 2012. Intrinsically photosensitive retinal ganglion cells are the primary but not exclusive circuit for light aversion. Exp Eye Res 105:60-9. PubMed: 23078956 MGI: J:203664
May A; Nimtschke U; May CA. 2009. The architecture of the mouse ciliary processes and their changes during retinal degeneration. Exp Eye Res 88(3):561-5. PubMed: 19059237 MGI: J:146578
May CA. 2009. Fibrae medullares in the retina of the RD mouse: a case report. Curr Eye Res 34(5):411-3. PubMed: 19401885 MGI: J:149565
McFadyen MP; Kusek G; Bolivar VJ; Flaherty L. 2003. Differences among eight inbred strains of mice in motor ability and motor learning on a rotorod. Genes Brain Behav 2(4):214-9. PubMed: 12953787 MGI: J:104873
McKenzie JA; Fruttiger M; Abraham S; Lange CA; Stone J; Gandhi P; Wang X; Bainbridge J; Moss SE; Greenwood J. 2012. Apelin is required for non-neovascular remodeling in the retina. Am J Pathol 180(1):399-409. PubMed: 22067912 MGI: J:180164
Meng R; Wu J; Harper DC; Wang Y; Kowalska MA; Abrams CS; Brass LF; Poncz M; Stalker TJ; Marks MS. 2015. Defective release of alpha granule and lysosome contents from platelets in mouse Hermansky-Pudlak syndrome models. Blood 125(10):1623-32. PubMed: 25477496 MGI: J:221384
Menu dit Huart L; Lorentz O; Goureau O; Leveillard T; Sahel JA. 2004. DNA repair in the degenerating mouse retina. Mol Cell Neurosci 26(3):441-9. PubMed: 15234348 MGI: J:109747
Menzler J; Channappa L; Zeck G. 2014. Rhythmic ganglion cell activity in bleached and blind adult mouse retinas. PLoS One 9(8):e106047. PubMed: 25153888 MGI: J:219242
Menzler J; Zeck G. 2011. Network oscillations in rod-degenerated mouse retinas. J Neurosci 31(6):2280-91. PubMed: 21307264 MGI: J:169452
Mitton KP; Guzman AE; Deshpande M; Byrd D; DeLooff C; Mkoyan K; Zlojutro P; Wallace A; Metcalf B; Laux K; Sotzen J; Tran T. 2014. Different effects of valproic acid on photoreceptor loss in Rd1 and Rd10 retinal degeneration mice. Mol Vis 20:1527-44. PubMed: 25489226 MGI: J:220255
Mohand-Said S; Deudon-Combe A; Hicks D; Simonutti M; Forster V ; Fintz AC ; Leveillard T ; Dreyfus H ; Sahel JA. 1998. Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse. Proc Natl Acad Sci U S A 95(14):8357-62. PubMed: 9653191 MGI: J:48731
Molnar T; Barabas P; Birnbaumer L; Punzo C; Kefalov V; Krizaj D. 2012. Store-operated channels regulate intracellular calcium in mammalian rods. J Physiol 590(Pt 15):3465-81. PubMed: 22674725 MGI: J:200207
Montana CL; Kolesnikov AV; Shen SQ; Myers CA; Kefalov VJ; Corbo JC. 2013. Reprogramming of adult rod photoreceptors prevents retinal degeneration. Proc Natl Acad Sci U S A 110(5):1732-7. PubMed: 23319618 MGI: J:193697
Morin LP; Studholme KM. 2011. Separation of function for classical and ganglion cell photoreceptors with respect to circadian rhythm entrainment and induction of photosomnolence. Neuroscience 199:213-24. PubMed: 21985934 MGI: J:184037
Mrosovsky N; Foster RG; Salmon PA. 1999. Thresholds for masking responses to light in three strains of retinally degenerate mice. J Comp Physiol [A] 184(4):423-8. PubMed: 10377976 MGI: J:56471
Mrosovsky N; Hampton RR. 1997. Spatial responses to light in mice with severe retinal degeneration. Neurosci Lett 222(3):204-6. PubMed: 9148250 MGI: J:40689
Mure LS; Hatori M; Zhu Q; Demas J; Kim IM; Nayak SK; Panda S. 2016. Melanopsin-Encoded Response Properties of Intrinsically Photosensitive Retinal Ganglion Cells. Neuron 90(5):1016-27. PubMed: 27181062 MGI: J:239646
Nakamura K; Harada C; Okumura A; Namekata K; Mitamura Y; Yoshida K; Ohno S; Yoshida H; Harada T. 2005. Effect of p75NTR on the regulation of photoreceptor apoptosis in the rd mouse. Mol Vis 11:1229-35. PubMed: 16402023 MGI: J:136765
Namekata K; Okumura A; Harada C; Nakamura K; Yoshida H; Harada T. 2006. Effect of photoreceptor degeneration on RNA splicing and expression of AMPA receptors. Mol Vis 12:1586-93. PubMed: 17200657 MGI: J:117332
Nishiguchi KM; Carvalho LS; Rizzi M; Powell K; Holthaus SM; Azam SA; Duran Y; Ribeiro J; Luhmann UF; Bainbridge JW; Smith AJ; Ali RR. 2015. Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179. Nat Commun 6:6006. PubMed: 25613321 MGI: J:219703
Nishiguchi KM; Nakamura M; Kaneko H; Kachi S; Terasaki H. 2007. The role of VEGF and VEGFR2/Flk1 in proliferation of retinal progenitor cells in murine retinal degeneration. Invest Ophthalmol Vis Sci 48(9):4315-20. PubMed: 17724222 MGI: J:126933
Nishikawa S; LaVail MM. 1998. Neovascularization of the RPE: temporal differences in mice with rod photoreceptor gene defects. Exp Eye Res 67(5):509-15. PubMed: 9878212 MGI: J:52112
Nivison-Smith L; Zhu Y; Whatham A; Bui BV; Fletcher EL; Acosta ML; Kalloniatis M. 2014. Sildenafil alters retinal function in mouse carriers of retinitis pigmentosa. Exp Eye Res 128:43-56. PubMed: 25239397 MGI: J:230189
Nuhn JS; Fuerst PG. 2014. Developmental localization of adhesion and scaffolding proteins at the cone synapse. Gene Expr Patterns 16(1):36-50. PubMed: 25176525 MGI: J:216508
O'Leary TP; Brown RE. 2009. Visuo-spatial learning and memory deficits on the Barnes maze in the 16-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease. Behav Brain Res 201(1):120-7. PubMed: 19428625 MGI: J:148386
Ogilvie JM; Hakenewerth AM; Gardner RR; Martak JG; Maggio VM. 2009. Dopamine receptor loss of function is not protective of rd1 rod photoreceptors in vivo. Mol Vis 15:2868-78. PubMed: 20038975 MGI: J:157088
Otani A; Kojima H; Guo C; Oishi A; Yoshimura N. 2012. Low-dose-rate, low-dose irradiation delays neurodegeneration in a model of retinitis pigmentosa. Am J Pathol 180(1):328-36. PubMed: 22074737 MGI: J:180155
Owens L; Buhr E; Tu DC; Lamprecht TL; Lee J; Van Gelder RN. 2012. Effect of circadian clock gene mutations on nonvisual photoreception in the mouse. Invest Ophthalmol Vis Sci 53(1):454-60. PubMed: 22159024 MGI: J:191526
Panda S; Provencio I; Tu DC; Pires SS; Rollag MD; Castrucci AM; Pletcher MT; Sato TK; Wiltshire T; Andahazy M; Kay SA; Van Gelder RN; Hogenesch JB. 2003. Melanopsin is required for non-image-forming photic responses in blind mice. Science 301(5632):525-7. PubMed: 12829787 MGI: J:165769
Panda S; Sato TK; Castrucci AM; Rollag MD; DeGrip WJ; Hogenesch JB; Provencio I; Kay SA. 2002. Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting. Science 298(5601):2213-6. PubMed: 12481141 MGI: J:81501
Pang J; Cheng M; Haire SE; Barker E; Planelles V; Blanks JC. 2006. Efficiency of lentiviral transduction during development in normal and rd mice. Mol Vis 12:756-67. PubMed: 16862069 MGI: J:111621
Paper W; Kroeber M; Heersink S; Stephan DA; Fuchshofer R; Russell P; Tamm ER. 2008. Elevated amounts of myocilin in the aqueous humor of transgenic mice cause significant changes in ocular gene expression. Exp Eye Res 87(3):257-67. PubMed: 18602390 MGI: J:141881
Paquet-Durand F ; Hauck SM ; van Veen T ; Ueffing M ; Ekstrom P. 2009. PKG activity causes photoreceptor cell death in two retinitis pigmentosa models. J Neurochem 108(3):796-810. PubMed: 19187097 MGI: J:146653
Paquet-Durand F; Azadi S; Hauck SM; Ueffing M; van Veen T; Ekstrom P. 2006. Calpain is activated in degenerating photoreceptors in the rd1 mouse. J Neurochem 96(3):802-14. PubMed: 16405498 MGI: J:106017
Paquet-Durand F; Beck S; Michalakis S; Goldmann T; Huber G; Muhlfriedel R; Trifunovic D; Fischer MD; Fahl E; Duetsch G; Becirovic E; Wolfrum U; van Veen T; Biel M; Tanimoto N; Seeliger MW. 2011. A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa. Hum Mol Genet 20(5):941-7. PubMed: 21149284 MGI: J:169039
Park H; Tan CC; Faulkner A; Jabbar SB; Schmid G; Abey J; Iuvone PM; Pardue MT. 2013. Retinal degeneration increases susceptibility to myopia in mice. Mol Vis 19:2068-79. PubMed: 24146540 MGI: J:205341
Park SJ; Lee DS; Lim EJ; Choi SH; Kang WS; Kim IB; Chun MH. 2008. The absence of the clathrin-dependent endocytosis in rod bipolar cells of the FVB/N mouse retina. Neurosci Lett 439(2):165-9. PubMed: 18514403 MGI: J:137049
Peirson SN; Oster H; Jones SL; Leitges M; Hankins MW; Foster RG. 2007. Microarray analysis and functional genomics identify novel components of melanopsin signaling. Curr Biol 17(16):1363-72. PubMed: 17702581 MGI: J:128396
Peng GH; Chen S. 2007. Crx activates opsin transcription by recruiting HAT-containing co-activators and promoting histone acetylation. Hum Mol Genet 16(20):3433-52. PubMed: 17656371 MGI: J:129889
Pennesi ME; Michaels KV; Magee SS; Maricle A; Davin SP; Garg AK; Gale MJ; Tu DC; Wen Y; Erker LR; Francis PJ. 2012. Long-term characterization of retinal degeneration in rd1 and rd10 mice using spectral domain optical coherence tomography. Invest Ophthalmol Vis Sci 53(8):4644-56. PubMed: 22562504 MGI: J:213983
Petrasch-Parwez E; Habbes HW; Weickert S; Lobbecke-Schumacher M; Striedinger K; Wieczorek S; Dermietzel R; Epplen JT. 2004. Fine-structural analysis and connexin expression in the retina of a transgenic model of Huntington's disease. J Comp Neurol 479(2):181-97. PubMed: 15452853 MGI: J:135880
Phelan JK; Bok D. 2000. Analysis and quantitation of mRNAs encoding the alpha- and beta-subunits of rod photoreceptor cGMP phosphodiesterase in neonatal retinal degeneration (rd) mouse retinas. Exp Eye Res 71(2):119-28. PubMed: 10930317 MGI: J:63861
Pickard GE; Baver SB; Ogilvie MD; Sollars PJ. 2009. Light-induced fos expression in intrinsically photosensitive retinal ganglion cells in melanopsin knockout (opn4) mice. PLoS One 4(3):e4984. PubMed: 19319185 MGI: J:147460
Pittler SJ; Baehr W. 1991. Identification of a nonsense mutation in the rod photoreceptor cGMP phosphodiesterase beta-subunit gene of the rd mouse. Proc Natl Acad Sci U S A 88(19):8322-6. PubMed: 1656438 MGI: J:11513
Pittler SJ; Keeler CE; Sidman RL; Baehr W. 1993. PCR analysis of DNA from 70-year-old sections of rodless retina demonstrates identity with the mouse rd defect. Proc Natl Acad Sci U S A 90(20):9616-9. PubMed: 8415750 MGI: J:15231
Popper P; Farber DB; Micevych PE; Minoofar K; Bronstein JM. 1997. TRPM-2 expression and tunel staining in neurodegenerative diseases: studies in wobbler and rd mice. Exp Neurol 143(2):246-54. PubMed: 9056387 MGI: J:38831
Portera-Cailliau C; Sung CH; Nathans J; Adler R. 1994. Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa. Proc Natl Acad Sci U S A 91(3):974-8. PubMed: 8302876 MGI: J:16708
Prigge CL; Yeh PT; Liou NF; Lee CC; You SF; Liu LL; McNeill DS; Chew KS; Hattar S; Chen SK; Zhang DQ. 2016. M1 ipRGCs Influence Visual Function through Retrograde Signaling in the Retina. J Neurosci 36(27):7184-97. PubMed: 27383593 MGI: J:234637
Provencio I; Cooper HM; Foster RG. 1998. Retinal projections in mice with inherited retinal degeneration: implications for circadian photoentrainment. J Comp Neurol 395(4):417-39. PubMed: 9619497 MGI: J:47756
Provencio I; Foster RG. 1995. Circadian rhythms in mice can be regulated by photoreceptors with cone-like characteristics. Brain Res 694(1-2):183-90. PubMed: 8974643 MGI: J:29236
Provencio I; Wong S; Lederman AB; Argamaso SM; Foster RG. 1994. Visual and circadian responses to light in aged retinally degenerate mice. Vision Res 34(14):1799-806. PubMed: 7941382 MGI: J:19843
Punzo C; Cepko C. 2007. Cellular responses to photoreceptor death in the rd1 mouse model of retinal degeneration. Invest Ophthalmol Vis Sci 48(2):849-57. PubMed: 17251487 MGI: J:123282
Punzo C; Kornacker K; Cepko CL. 2009. Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa. Nat Neurosci 12(1):44-52. PubMed: 19060896 MGI: J:144720
Qiao X; Pennesi M; Seong E; Gao H; Burmeister M; Wu SM. 2003. Photoreceptor degeneration and rd1 mutation in the grizzled/mocha mouse strain. Vision Res 43(8):859-65. PubMed: 12668055 MGI: J:88031
RIKEN BioResource Center/RIKEN Genomic Sciences Center. 2008. A Large Scale Mutagenesis Program in RIKEN GSC PhenoSITE, World Wide Web (URL: http://www.brc.riken.jp/lab/gsc/mouse/) :. MGI: J:133634
Rao A; Dallman R; Henderson S; Chen CK. 2007. Gbeta5 is required for normal light responses and morphology of retinal ON-bipolar cells. J Neurosci 27(51):14199-204. PubMed: 18094259 MGI: J:129267
Rattner A; Wang Y; Zhou Y; Williams J; Nathans J. 2014. The role of the hypoxia response in shaping retinal vascular development in the absence of Norrin/Frizzled4 signaling. Invest Ophthalmol Vis Sci 55(12):8614-25. PubMed: 25414188 MGI: J:230295
Read DS; McCall MA; Gregg RG. 2002. Absence of voltage-dependent calcium channels delays photoreceptor degeneration in rd mice. Exp Eye Res 75(4):415-20. PubMed: 12387789 MGI: J:79923
Rich KA; Zhan Y; Blanks JC. 1997. Migration and synaptogenesis of cone photoreceptors in the developing mouse retina. J Comp Neurol 388(1):47-63. PubMed: 9364238 MGI: J:44100
Roesch K; Stadler MB; Cepko CL. 2012. Gene expression changes within Muller glial cells in retinitis pigmentosa. Mol Vis 18:1197-214. PubMed: 22665967 MGI: J:191614
Rohrer B; Demos C; Frigg R; Grimm C. 2007. Classical complement activation and acquired immune response pathways are not essential for retinal degeneration in the rd1 mouse. Exp Eye Res 84(1):82-91. PubMed: 17069800 MGI: J:123183
Rossi C; Strettoi E; Galli-Resta L. 2003. The spatial order of horizontal cells is not affected by massive alterations in the organization of other retinal cells. J Neurosci 23(30):9924-8. PubMed: 14586022 MGI: J:120041
Ruan GX; Allen GC; Yamazaki S; McMahon DG. 2008. An autonomous circadian clock in the inner mouse retina regulated by dopamine and GABA. PLoS Biol 6(10):e249. PubMed: 18959477 MGI: J:141081
Ruggiero L; Allen CN; Lane Brown R; Robinson DW. 2009. The development of melanopsin-containing retinal ganglion cells in mice with early retinal degeneration. Eur J Neurosci 29(2):359-67. PubMed: 19200239 MGI: J:146465
Ryu SB; Ye JH; Goo YS; Kim CH; Kim KH. 2010. Temporal response properties of retinal ganglion cells in rd1 mice evoked by amplitude-modulated electrical pulse trains. Invest Ophthalmol Vis Sci 51(12):6762-9. PubMed: 20671284 MGI: J:171389
SIDMAN RL; GREEN MC. 1965. RETINAL DEGENERATION IN THE MOUSE: LOCATION OF THE RD LOCUS IN LINKAGE GROUP XVII. J Hered 56:23-9. PubMed: 14276177 MGI: J:114
Sahaboglu A; Tanimoto N; Kaur J; Sancho-Pelluz J; Huber G; Fahl E; Arango-Gonzalez B; Zrenner E; Ekstrom P; Lowenheim H; Seeliger M; Paquet-Durand F. 2010. PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function. PLoS One 5(11):e15495. PubMed: 21124852 MGI: J:167317
Samardzija M; Wenzel A; Aufenberg S; Thiersch M; Reme C; Grimm C. 2006. Differential role of Jak-STAT signaling in retinal degenerations. FASEB J 20(13):2411-3. PubMed: 16966486 MGI: J:114638
Samardzija M; Wenzel A; Thiersch M; Frigg R; Reme C; Grimm C. 2006. Caspase-1 ablation protects photoreceptors in a model of autosomal dominant retinitis pigmentosa. Invest Ophthalmol Vis Sci 47(12):5181-90. PubMed: 17122101 MGI: J:123100
Sancho-Pelluz J; Wunderlich KA; Rauch U; Romero FJ; van Veen T; Limb GA; Crocker PR; Perez MT. 2008. Sialoadhesin expression in intact degenerating retinas and following transplantation. Invest Ophthalmol Vis Sci 49(12):5602-10. PubMed: 18641281 MGI: J:142000
Sanz MM; Johnson LE; Ahuja S; Ekstrom PA; Romero J; van Veen T. 2007. Significant photoreceptor rescue by treatment with a combination of antioxidants in an animal model for retinal degeneration. Neuroscience 145(3):1120-9. PubMed: 17293057 MGI: J:121644
Sasahara M; Otani A; Oishi A; Kojima H; Yodoi Y; Kameda T; Nakamura H; Yoshimura N. 2008. Activation of bone marrow-derived microglia promotes photoreceptor survival in inherited retinal degeneration. Am J Pathol 172(6):1693-703. PubMed: 18483210 MGI: J:136339
Schmidt SY; Lolley RN. 1973. Cyclic-nucleotide phosphodiesterase: an early defect in inherited retinal degeneration of C3H mice. J Cell Biol 57(1):117-23. PubMed: 4347974 MGI: J:5332
Scott A; Powner MB; Fruttiger M. 2014. Quantification of vascular tortuosity as an early outcome measure in oxygen induced retinopathy (OIR). Exp Eye Res 120:55-60. PubMed: 24418725 MGI: J:210367
Selby CP; Thompson C; Schmitz TM; Van Gelder RN; Sancar A. 2000. Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice Proc Natl Acad Sci U S A 97(26):14697-702. PubMed: 11114194 MGI: J:66580
Semo M; Gias C; Ahmado A; Sugano E; Allen AE; Lawrence JM; Tomita H; Coffey PJ; Vugler AA. 2010. Dissecting a role for melanopsin in behavioural light aversion reveals a response independent of conventional photoreception. PLoS One 5(11):e15009. PubMed: 21124784 MGI: J:167120
Semo M; Lupi D; Peirson SN; Butler JN; Foster RG. 2003. Light-induced c-fos in melanopsin retinal ganglion cells of young and aged rodless/coneless (rd/rd cl) mice. Eur J Neurosci 18(11):3007-17. PubMed: 14656296 MGI: J:89691
Semo M; Peirson S; Lupi D; Lucas RJ; Jeffery G; Foster RG. 2003. Melanopsin retinal ganglion cells and the maintenance of circadian and pupillary responses to light in aged rodless/coneless (rd/rd cl) mice. Eur J Neurosci 17(9):1793-801. PubMed: 12752778 MGI: J:128149
Sharma AK; Rohrer B. 2007. Sustained elevation of intracellular cGMP causes oxidative stress triggering calpain-mediated apoptosis in photoreceptor degeneration. Curr Eye Res 32(3):259-69. PubMed: 17453946 MGI: J:121112
Sheedlo HJ; Jaynes D; Bolan AL; Turner JE. 1995. Mullerian glia in dystrophic rodent retinas: an immunocytochemical analysis. Brain Res Dev Brain Res 85(2):171-80. PubMed: 7600664 MGI: J:24543
Sooy K; Noble J; McBride A; Binnie M; Yau JL; Seckl JR; Walker BR; Webster SP. 2015. Cognitive and Disease-Modifying Effects of 11beta-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease. Endocrinology 156(12):4592-603. PubMed: 26305888 MGI: J:232753
Srinivasan Y; Lovicu FJ; Overbeek PA. 1998. Lens-specific expression of transforming growth factor beta1 in transgenic mice causes anterior subcapsular cataracts. J Clin Invest 101(3):625-34. PubMed: 9449696 MGI: J:135895
Srivastava P; Sinha-Mahapatra SK; Ghosh A; Srivastava I; Dhingra NK. 2015. Differential alterations in the expression of neurotransmitter receptors in inner retina following loss of photoreceptors in rd1 mouse. PLoS One 10(4):e0123896. PubMed: 25835503 MGI: J:233420
Stone C; Pinto LH. 1993. Response properties of ganglion cells in the isolated mouse retina. Vis Neurosci 10(1):31-9. PubMed: 8424927 MGI: J:116795
Strettoi E; Pignatelli V. 2000. Modifications of retinal neurons in a mouse model of retinitis pigmentosa Proc Natl Acad Sci U S A 97(20):11020-5. PubMed: 10995468 MGI: J:64742
Strettoi E; Pignatelli V; Rossi C; Porciatti V; Falsini B. 2003. Remodeling of second-order neurons in the retina of rd/rd mutant mice. Vision Res 43(8):867-77. PubMed: 12668056 MGI: J:92316
Strettoi E; Porciatti V; Falsini B; Pignatelli V; Rossi C. 2002. Morphological and functional abnormalities in the inner retina of the rd/rd mouse. J Neurosci 22(13):5492-504. PubMed: 12097501 MGI: J:109225
Sumaya IC; Masana MI; Dubocovich ML. 2005. The antidepressant-like effect of the melatonin receptor ligand luzindole in mice during forced swimming requires expression of MT2 but not MT1 melatonin receptors. J Pineal Res 39(2):170-7. PubMed: 16098095 MGI: J:114318
Sun J; Mandai M; Kamao H; Hashiguchi T; Shikamura M; Kawamata S; Sugita S; Takahashi M. 2015. Protective Effects of Human iPS-Derived Retinal Pigmented Epithelial Cells in Comparison with Human Mesenchymal Stromal Cells and Human Neural Stem Cells on the Degenerating Retina in rd1 mice. Stem Cells 33(5):1543-53. PubMed: 25728228 MGI: J:224164
Syeda S; Patel AK; Lee T; Hackam AS. 2015. Reduced photoreceptor death and improved retinal function during retinal degeneration in mice lacking innate immunity adaptor protein MyD88. Exp Neurol 267:1-12. PubMed: 25725353 MGI: J:221046
Takahashi M; Miyoshi H; Verma IM; Gage FH. 1999. Rescue from photoreceptor degeneration in the rd mouse by human immunodeficiency virus vector-mediated gene transfer. J Virol 73(9):7812-6. PubMed: 10438872 MGI: J:56759
Tansley K. 1954. An inherited retinal degeneration in the mouse J Hered 45:123-27. MGI: J:15333
Thaung C; Arnold K; Jackson IJ; Coffey PJ. 2002. Presence of visual head tracking differentiates normal sighted from retinal degenerate mice. Neurosci Lett 325(1):21-4. PubMed: 12023058 MGI: J:107978
Thompson CL; Selby CP; Partch CL; Plante DT; Thresher RJ; Araujo F; Sancar A. 2004. Further evidence for the role of cryptochromes in retinohypothalamic photoreception/phototransduction. Brain Res Mol Brain Res 122(2):158-66. PubMed: 15010208 MGI: J:88468
Thompson S; Blodi FR; Lee S; Welder CR; Mullins RF; Tucker BA; Stasheff SF; Stone EM. 2014. Photoreceptor cells with profound structural deficits can support useful vision in mice. Invest Ophthalmol Vis Sci 55(3):1859-66. PubMed: 24569582 MGI: J:229505
Thompson S; Foster RG; Stone EM; Sheffield VC; Mrosovsky N. 2008. Classical and melanopsin photoreception in irradiance detection: negative masking of locomotor activity by light. Eur J Neurosci 27(8):1973-9. PubMed: 18412618 MGI: J:136825
Thompson S; Lupi D; Hankins MW; Peirson SN; Foster RG. 2008. The effects of rod and cone loss on the photic regulation of locomotor activity and heart rate. Eur J Neurosci 28(4):724-9. PubMed: 18702692 MGI: J:140577
Thompson S; Mullins RF; Philp AR; Stone EM; Mrosovsky N. 2008. Divergent phenotypes of vision and accessory visual function in mice with visual cycle dysfunction (Rpe65 rd12) or retinal degeneration (rd/rd). Invest Ophthalmol Vis Sci 49(6):2737-42. PubMed: 18515598 MGI: J:137044
Thompson S; Stasheff SF; Hernandez J; Nylen E; East JS; Kardon RH; Pinto LH; Mullins RF; Stone EM. 2011. Different inner retinal pathways mediate rod-cone input in irradiance detection for the pupillary light reflex and regulation of behavioral state in mice. Invest Ophthalmol Vis Sci 52(1):618-23. PubMed: 20847113 MGI: J:171559
Thyagarajan S; van Wyk M; Lehmann K; Lowel S; Feng G; Wassle H. 2010. Visual function in mice with photoreceptor degeneration and transgenic expression of channelrhodopsin 2 in ganglion cells. J Neurosci 30(26):8745-58. PubMed: 20592196 MGI: J:161847
Tochitsky I; Polosukhina A; Degtyar VE; Gallerani N; Smith CM; Friedman A; Van Gelder RN; Trauner D; Kaufer D; Kramer RH. 2014. Restoring visual function to blind mice with a photoswitch that exploits electrophysiological remodeling of retinal ganglion cells. Neuron 81(4):800-13. PubMed: 24559673 MGI: J:220643
Tsang SH; Gouras P; Yamashita CK; Kjeldbye H; Fisher J; Farber DB; Goff SP. 1996. Retinal degeneration in mice lacking the gamma subunit of the rod cGMP phosphodiesterase. Science 272(5264):1026-9. PubMed: 8638127 MGI: J:33048
Tu DC; Owens LA; Anderson L; Golczak M; Doyle SE; McCall M; Menaker M; Palczewski K; Van Gelder RN. 2006. Inner retinal photoreception independent of the visual retinoid cycle. Proc Natl Acad Sci U S A 103(27):10426-31. PubMed: 16788071 MGI: J:111700
Tu DC; Zhang D; Demas J; Slutsky EB; Provencio I; Holy TE; Van Gelder RN. 2005. Physiologic diversity and development of intrinsically photosensitive retinal ganglion cells. Neuron 48(6):987-99. PubMed: 16364902 MGI: J:107606
Tucker B; Klassen H; Yang L; Chen DF; Young MJ. 2008. Elevated MMP Expression in the MRL Mouse Retina Creates a Permissive Environment for Retinal Regeneration. Invest Ophthalmol Vis Sci 49(4):1686-95. PubMed: 18385092 MGI: J:136153
Usui S; Oveson BC; Lee SY; Jo YJ; Yoshida T; Miki A; Miki K; Iwase T; Lu L; Campochiaro PA. 2009. NADPH oxidase plays a central role in cone cell death in retinitis pigmentosa. J Neurochem 110(3):1028-37. PubMed: 19493169 MGI: J:152819
Van Gelder RN; Wee R; Lee JA; Tu DC. 2003. Reduced pupillary light responses in mice lacking cryptochromes. Science 299(5604):222. PubMed: 12522242 MGI: J:81500
Vazquez-Chona FR; Clark AM; Levine EM. 2009. Rlbp1 promoter drives robust Muller glial GFP expression in transgenic mice. Invest Ophthalmol Vis Sci 50(8):3996-4003. PubMed: 19324864 MGI: J:154561
Venkatesh A; Ma S; Le YZ; Hall MN; Ruegg MA; Punzo C. 2015. Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. J Clin Invest 125(4):1446-58. PubMed: 25798619 MGI: J:222273
Viczian A; Sanyal S; Toffenetti J; Chader GJ; Farber DB. 1992. Photoreceptor-specific mRNAs in mice carrying different allelic combinations at the rd and rds loci. Exp Eye Res 54(6):853-60. PubMed: 1381682 MGI: J:2579
Vlachantoni D; Bramall AN; Murphy MP; Taylor RW; Shu X; Tulloch B; Van Veen T; Turnbull DM; McInnes RR; Wright AF. 2011. Evidence of severe mitochondrial oxidative stress and a protective effect of low oxygen in mouse models of inherited photoreceptor degeneration. Hum Mol Genet 20(2):322-35. PubMed: 21051333 MGI: J:166898
Wahlin KJ; Adler R; Zack DJ; Campochiaro PA. 2001. Neurotrophic signaling in normal and degenerating rodent retinas. Exp Eye Res 73(5):693-701. PubMed: 11747369 MGI: J:73377
Wang Y; Wang ZY; Zhou MN; Cai J; Sun LY; Liu XY; Daugherty BL; Pestka S. 1997. Sequencing and bacterial expression of a novel murine alpha interferon gene. Sci China C Life Sci 40(3):277-283. MGI: J:41297
Warthen DM; Wiltgen BJ; Provencio I. 2011. Light enhances learned fear. Proc Natl Acad Sci U S A 108(33):13788-93. PubMed: 21808002 MGI: J:175610
Welge-Lussen U; Wilsch C; Neuhardt T; Wayne Streilein J; Lutjen-Drecoll E. 1999. Loss of anterior chamber-associated immune deviation (ACAID) in aged retinal degeneration (rd) mice. Invest Ophthalmol Vis Sci 40(13):3209-14. PubMed: 10586944 MGI: J:58745
Won J; Shi LY; Hicks W; Wang J; Hurd R; Naggert JK; Chang B; Nishina PM. 2011. Mouse model resources for vision research. J Ophthalmol 2011:391384. PubMed: 21052544 MGI: J:166679
Wong P; Borst DE; Farber D; Danciger JS; Tenniswood M; Chader GJ; van Veen T. 1994. Increased TRPM-2/clusterin mRNA levels during the time of retinal degeneration in mouse models of retinitis pigmentosa. Biochem Cell Biol 72(9-10):439-46. PubMed: 7605616 MGI: J:24128
Worthington KS; Wiley LA; Bartlett AM; Stone EM; Mullins RF; Salem AK; Guymon CA; Tucker BA. 2014. Mechanical properties of murine and porcine ocular tissues in compression. Exp Eye Res 121:194-9. PubMed: 24613781 MGI: J:229490
Wu J; Trogadis J; Bremner R. 2001. Rod and cone degeneration in the rd mouse is p53 independent. Mol Vis 7:101-6. PubMed: 11344337 MGI: J:126023
Wunderlich KA; Leveillard T; Penkowa M; Zrenner E; Perez MT. 2010. Altered expression of metallothionein-I and -II and their receptor megalin in inherited photoreceptor degeneration. Invest Ophthalmol Vis Sci 51(9):4809-20. PubMed: 20357188 MGI: J:164094
Xiong W; MacColl Garfinkel AE; Li Y; Benowitz LI; Cepko CL. 2015. NRF2 promotes neuronal survival in neurodegeneration and acute nerve damage. J Clin Invest 125(4):1433-45. PubMed: 25798616 MGI: J:222275
Yamada H; Yamada E; Hackett SF; Ozaki H; Okamoto N; Campochiaro PA. 1999. Hyperoxia causes decreased expression of vascular endothelial growth factor and endothelial cell apoptosis in adult retina. J Cell Physiol 179(2):149-56. PubMed: 10199554 MGI: J:54326
Yan W; Lewin A; Hauswirth W. 1998. Selective degradation of nonsense beta-phosphodiesterase mRNA in the heterozygous rd mouse. Invest Ophthalmol Vis Sci 39(13):2529-36. PubMed: 9856762 MGI: J:51361
Yang LP; Wu LM; Guo XJ; Tso MO. 2007. Activation of endoplasmic reticulum stress in degenerating photoreceptors of the rd1 mouse. Invest Ophthalmol Vis Sci 48(11):5191-8. PubMed: 17962473 MGI: J:127157
Yazulla S; Studholme KM; Pinto LH. 1997. Differences in the retinal GABA system among control, spastic mutant and retinal degeneration mutant mice. Vision Res 37(24):3471-82. PubMed: 9425524 MGI: J:45280
Yee CW; Toychiev AH; Ivanova E; Sagdullaev BT. 2014. Aberrant synaptic input to retinal ganglion cells varies with morphology in a mouse model of retinal degeneration. J Comp Neurol 522(18):4085-99. PubMed: 25099614 MGI: J:238192
Yi H; Nakamura RE; Mohamed O; Dufort D; Hackam AS. 2007. Characterization of Wnt signaling during photoreceptor degeneration. Invest Ophthalmol Vis Sci 48(12):5733-41. PubMed: 18055826 MGI: J:132500
Yoshimura T; Ebihara S. 1996. Spectral sensitivity of photoreceptors mediating phase-shifts of circadian rhythms in retinally degenerate CBA/J (rd/rd) and normal CBA/N (+/+)mice. J Comp Physiol [A] 178(6):797-802. PubMed: 8667293 MGI: J:33685
Yoshimura T; Ebihara S. 1998. Decline of circadian photosensitivity associated with retinal degeneration in CBA/J-rd/rd mice. Brain Res 779(1-2):188-93. PubMed: 9473668 MGI: J:45462
Yoshimura T; Nishio M; Goto M; Ebihara S. 1994. Differences in circadian photosensitivity between retinally degenerate CBA/J mice (rd/rd) and normal CBA/N mice (+/+). J Biol Rhythms 9(1):51-60. PubMed: 7949306 MGI: J:19351
Yoshimura T; Yokota Y; Ishikawa A; Yasuo S; Hayashi N; Suzuki T; Okabayashi N; Namikawa T; Ebihara S. 2002. Mapping quantitative trait loci affecting circadian photosensitivity in retinally degenerate mice. J Biol Rhythms 17(6):512-9. PubMed: 12465884 MGI: J:80788
Zeiss CJ; Johnson EA. 2004. Proliferation of microglia, but not photoreceptors, in the outer nuclear layer of the rd-1 mouse. Invest Ophthalmol Vis Sci 45(3):971-6. PubMed: 14985319 MGI: J:109731
Zeiss CJ; Neal J; Johnson EA. 2004. Caspase-3 in postnatal retinal development and degeneration. Invest Ophthalmol Vis Sci 45(3):964-70. PubMed: 14985318 MGI: J:88367
Zencak D; Crippa SV; Tekaya M; Tanger E; Schorderet DE; Munier FL; van Lohuizen M; Arsenijevic Y. 2006. BMI1 loss delays photoreceptor degeneration in Rd1 mice. Bmi1 loss and neuroprotection in Rd1 mice. Adv Exp Med Biol 572:209-15. PubMed: 17249577 MGI: J:154016
Zencak D; Schouwey K; Chen D; Ekstrom P; Tanger E; Bremner R; van Lohuizen M; Arsenijevic Y. 2013. Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins. Proc Natl Acad Sci U S A 110(7):E593-601. PubMed: 23359713 MGI: J:194322
Zeng H; Ding M; Chen XX; Lu Q. 2014. Microglial NADPH oxidase activation mediates rod cell death in the retinal degeneration in rd mice. Neuroscience 275:54-61. PubMed: 24929065 MGI: J:215397
Zeng HY; Lu QJ; Liu Q; Liu KG; Wang NL. 2011. The role of CCR1 expression in the retinal degeneration in rd mice. Curr Eye Res 36(3):264-9. PubMed: 21275605 MGI: J:179793
Zhang N; Kolesnikov AV; Jastrzebska B; Mustafi D; Sawada O; Maeda T; Genoud C; Engel A; Kefalov VJ; Palczewski K. 2013. Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization. J Clin Invest 123(1):121-37. PubMed: 23221340 MGI: J:194158
Zhao L; Zabel MK; Wang X; Ma W; Shah P; Fariss RN; Qian H; Parkhurst CN; Gan WB; Wong WT. 2015. Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration. EMBO Mol Med 7(9):1179-97. PubMed: 26139610 MGI: J:233541
Zhu Y; Tu DC; Denner D; Shane T; Fitzgerald CM; Van Gelder RN. 2007. Melanopsin-dependent persistence and photopotentiation of murine pupillary light responses. Invest Ophthalmol Vis Sci 48(3):1268-75. PubMed: 17325172 MGI: J:123259
van Oosterhout F; Fisher SP; van Diepen HC; Watson TS; Houben T; VanderLeest HT; Thompson S; Peirson SN; Foster RG; Meijer JH. 2012. Ultraviolet light provides a major input to non-image-forming light detection in mice. Curr Biol 22(15):1397-402. PubMed: 22771039 MGI: J:199506
van Wyk M; Pielecka-Fortuna J; Lowel S; Kleinlogel S. 2015. Restoring the ON Switch in Blind Retinas: Opto-mGluR6, a Next-Generation, Cell-Tailored Optogenetic Tool. PLoS Biol 13(5):e1002143. PubMed: 25950461 MGI: J:222959

Genetic overview

Research Applications

Base Price

Important Note

Detailed Description

Development

Selected References

Ahrb-2

Allele Symbol: Ahrb-2

Bmp5se

Allele Symbol: Bmp5se

Cdh23ahl

Allele Symbol: Cdh23ahl

Gpr84del

Allele Symbol: Gpr84del

Myo5ad

Allele Symbol: Myo5ad

Pde6brd1

Allele Symbol: Pde6brd1

Disease Terms

Research Areas By Genotype

This mouse can be used to support research in many areas including:

Genotype: Bmp5se related

Genotype: Cdh23ahl related

Genotype: Myo5ad related

Genotype: Pde6brd1 related

Phenotype Information

References

Additional References

Additional - Ahrb-2 related

Additional - Bmp5se related

Additional - Cdh23ahl related

Additional - Gpr84del related

Additional - Myo5ad related

Additional - Pde6brd1 related

Genotyping Protocols

Dietary Information

Appearance

Citation

Animal Health Reports

Production of mice from cryopreserved embryos or sperm occurs in a maximum barrier room, G200

Live Mouse

Cryorecovery - Pricing

Progeny testing is not required

Payment Terms and Conditions

The Jackson Laboratory's Genotype Promise

Terms of Use

Licensing Information

JAX® Mice, Products & Services Conditions of Use

No Warranty

Credit for PRODUCTS or SERVICES

Animal Care and Use for SERVICES

No Liability

Ahr^b-2

Allele Symbol: Ahr^b-2

Bmp5^se

Allele Symbol: Bmp5^se

Cdh23^ahl

Allele Symbol: Cdh23^ahl

Gpr84^del

Allele Symbol: Gpr84^del

Myo5a^d

Allele Symbol: Myo5a^d

Pde6b^rd1

Allele Symbol: Pde6b^rd1

Genotype: Bmp5^se related

Genotype: Cdh23^ahl related

Genotype: Myo5a^d related

Genotype: Pde6b^rd1 related

Additional - Ahr^b-2 related

Additional - Bmp5^se related

Additional - Cdh23^ahl related

Additional - Gpr84^del related

Additional - Myo5a^d related

Additional - Pde6b^rd1 related