Overview

Also Known As:D1, DBA1, DBA, DBA/1

DBA/1J mice are widely used as a model for rheumatoid arthritis: immunization with type II collagen leads to the development of severe polyarthritis mediated by an autoimmune response. DBA/1J mice show an intermediate susceptibility to developing atherosclerotic aortic lesions on an atherogenic diet. In response to challenge, DBA/1J mice develop immune-mediated nephritis characterized by proteinuria, glomerulonephritis and tubulointerstitial disease.

Genetic overview

Genetic Background	Generation

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Research Applications

Mouse/Human Gene Homologs
Dermatology Research
Immunology, Inflammation and Autoimmunity Research
Neurobiology Research
Sensorineural Research
Hematological Research
Research Tools

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Base Price

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$40.89 Domestic price for female 3-week

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Details

Important Note

This strain is homozygous for Cdh23^ahl, the age related hearing loss 1 mutation, which on this background results in progressive hearing loss with onset after 10 months of age.

Detailed Description

DBA/1J mice are widely used as a model for rheumatoid arthritis: immunization with type II collagen leads to the development of severe polyarthritis mediated by an autoimmune response. The incidence of collagen induced arthritis varies by experimental protocol, but is less than 100%. Similar to the human condition, mice with collagen-induced arthritis display synovitis and erosions of cartilage and bone. In addition, susceptibility in both humans and mice is linked to the expression of specific MHC class II molecules. DBA/1J mice show an intermediate susceptibility to developing atherosclerotic aortic lesions on an atherogenic diet. In response to challenge, DBA/1J mice develop immune-mediated nephritis characterized by proteinuria, glomerulonephritis and tubulointerstitial disease (Xie et al., 2004). There is high incidence of calcified lesions of the tongue with age. This strain is among the least responsive to phytohemagglutinin (Heiniger et al., 1975).

Development

The DBA inbred strain is the oldest of all inbred strains of mice. Dr. CC Little began inbreeding in 1909 from a mouse colony segregating for coat color. During 1929 and 1930 crosses were made among substrains, and several new substrains were established including DBA/1 and DBA/2. DBA/1 and DBA/2 differ at a large number of loci (including the MHC H2 haplotype) which most likely results from residual heterozygosity in the strain when the substrains were separated.

Selected References

Doran AG; Wong K; Flint J; Adams DJ; Hunter KW; Keane TM. 2016. Deep genome sequencing and variation analysis of 13 inbred mouse strains defines candidate phenotypic alleles, private variation and homozygous truncating mutations. Genome Biol 17(1):167PubMed: 27480531 MGI: J:262923
Kato F; Nomura M; Nakamura K. 1996. Arthritis in mice induced by a single immunisation with collagen. Ann Rheum Dis 55(8):535-9PubMed: 8774181 MGI: J:109907
Lories RJ; Derese I; Luyten FP. 2005. Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis. J Clin Invest 115(6):1571-9PubMed: 15902307 MGI: J:109831
Lories RJ; Matthys P; de Vlam K; Derese I; Luyten FP. 2004. Ankylosing enthesitis, dactylitis, and onychoperiostitis in male DBA/1 mice: a model of psoriatic arthritis. Ann Rheum Dis 63(5):595-8PubMed: 15082495 MGI: J:109840
Matthys P; Lories RJ; De Klerck B; Heremans H; Luyten FP; Billiau A. 2003. Dependence on interferon-gamma for the spontaneous occurrence of arthritis in DBA/1 mice. Arthritis Rheum 48(10):2983-8PubMed: 14558106 MGI: J:106277
McIndoe RA; Bohlman B; Chi E; Schuster E; Lindhardt M; Hood L. 1999. Localization of non-Mhc collagen-induced arthritis susceptibility loci in DBA/1j mice. Proc Natl Acad Sci U S A 96(5):2210-4PubMed: 10051620 MGI: J:53356
Myers LK; Rosloniec EF; Cremer MA; Kang AH. 1997. Collagen-induced arthritis, an animal model of autoimmunity. Life Sci 61(19):1861-78PubMed: 9364191 MGI: J:109904
Paigen B; Morrow A; Brandon C; Mitchell D; Holmes P. 1985. Variation in susceptibility to atherosclerosis among inbred strains of mice. Atherosclerosis 57(1):65-73PubMed: 3841001 MGI: J:109950
Petkov PM; Cassell MA; Sargent EE; Donnelly CJ; Robinson P; Crew V; Asquith S; Haar RV; Wiles MV. 2004. Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse. Genomics 83(5):902-11PubMed: 15081119 MGI: J:89298
Timmermans S; Van Montagu M; Libert C. 2017. Complete overview of protein-inactivating sequence variations in 36 sequenced mouse inbred strains. Proc Natl Acad Sci U S A 114(34):9158-9163PubMed: 28784771 MGI: J:244295
Xie C; Sharma R; Wang H; Zhou XJ; Mohan C. 2004. Strain distribution pattern of susceptibility to immune-mediated nephritis. J Immunol 172(8):5047-55PubMed: 15067087 MGI: J:122988

View All References

Genetics

a

Allele Symbol: a

Allele Name	nonagouti
Allele Type	Spontaneous
Allele Synonym(s)
Gene Symbol and Name	a, nonagouti
Gene Synonym(s)
Strain of Origin	old mutant of the mouse fancy
Chromosome	2
General Note	Insertion of the LV30 retrotransposon without the beta4 retrovirus sequence does not cause the nonagouti phenotype. J:278039
Molecular Note	Characterization of this allele shows an insertion of DNA comprised of a 5.5kb virus-like element, VL30, into the first intron of the agouti gene. The VL30 element itself contains an additional 5.5 kb sequence, flanked by 526 bp of direct repeats (beta4 retroviral sequence). The host integration site is the same as for a^t-2Gso and A^w-38J and includes a duplication of four nucleotides of host DNA and a deletion of 2 bp from the end of each repeat. Northern analysis of mRNA from skin of homozygotes shows a smaller agouti message and levels 8 fold lower than found in wild-type.

Tyrp1^b

Allele Symbol: Tyrp1^b

Allele Name	brown
Allele Type	Spontaneous
Allele Synonym(s)	b
Gene Symbol and Name	Tyrp1, tyrosinase-related protein 1
Gene Synonym(s)
Strain of Origin	old mutant of the mouse fancy
Chromosome	4
Molecular Note	A G-to-A transition point mutation at position 329 was shown by revertant analysis to be responsible for the mutant phenotype seen in the brown mutant. This mutation changes cysteine to tyrosine at position 110 (p.C110Y) in the encoded protein. Three other point mutations in the brown sequence were identified, but do not contribute to the mutant phenotype.

Myo5a^d

Allele Symbol: Myo5a^d

Allele Name	dilute
Allele Type	Spontaneous
Allele Synonym(s)	blue dilution; d; d^v; Maltese dilution
Gene Symbol and Name	Myo5a, myosin VA
Gene Synonym(s)
Strain of Origin	old mutant of the mouse fancy
Chromosome	9
Molecular Note	This mutation is the result of the integration of ecotropic murine leukemia virus Emv-3 into a noncoding region of the Myo5a^d gene. Reversions of Myo5a^d to wild-type are caused by excision of the virus leaving exactly one long terminal repeat in place.

Hbb^d

Allele Symbol: Hbb^d

Allele Name	d
Allele Type	Not Applicable
Allele Synonym(s)
Gene Symbol and Name	Hbb, hemoglobin beta chain complex
Gene Synonym(s)
Strain of Origin	BALB/c
Chromosome	7

Cdh23^ahl

Allele Symbol: Cdh23^ahl

Allele Name	age related hearing loss 1
Allele Type	Spontaneous
Allele Synonym(s)	Cdh23^753A; mdfw
Gene Symbol and Name	Cdh23, cadherin 23 (otocadherin)
Gene Synonym(s)
Strain of Origin	multiple strains
Chromosome	10
Molecular Note	Genetic complementation tests have shown allelism between the mdfw (modifier of deaf waddler) locus and the ahl locus. Further analysis has shown this is caused by a G to A transition at coding nucleotide position 753 of Cdh23 (SNP rs257098870). This hypomorphic allele changes splice donor site G-GT to A-GT, causing frame skipping of exon 7. This is predicted to delete part of the 2nd and 3rd ectodomains and cause reduced message stability. Twenty-seven strains classified with ahl and carrying the 753A allele include: CD-1, RBF/DnJ, PL/J, AKR/J, RF/J, BALB/cBy, A/WySnJ, P/J, SENCARA/PtJ, DBA/1J, ALS/LtJ, C58/J, C57BLKS/J, 129P1/ReJ, C57BR/cd, SKH2/J, BUB/Bn, MA/MyJ, LP/J, 129X1/SvJ, NOR/LtJ, A/J, C57BL/6, NOD/LtJ, DBA/2J, ALR/LtJ, C57L/J. Strains classified with ahl that DO NOT carry this mutation include: 129S1/SvImJ, C3H/HeSnJ, I/LnJ, YBR/Ei, MRL/MpJ.

P2rx7^rs48804829-T

Allele Symbol: P2rx7^rs48804829-T

Allele Name	rs48804829 SNP allele with the T variant
Allele Type	Spontaneous
Allele Synonym(s)	P2rx7^P451L
Gene Symbol and Name	P2rx7, purinergic receptor P2X, ligand-gated ion channel, 7
Gene Synonym(s)
Strain of Origin	various
Chromosome	5
Molecular Note	The T variant of SNP rs48804829 at coding nucleotide 1352 codes for a leucine at codon 451 which yields a peptide with severely reduced activity. This variant is found in AKR/J, C3H/HeJ, C57BL/6, C57BL/10, CBA/J, DBA/1, DBA/2, FVB/NJ, and NZO/HILtJ. The wild-type C variant, coding for proline, is found in 129P2/OlaHsd, 129S1/SvImJ, 129S5SvEvBrd, A/J, BALB/c, CAST/EiJ ,NZW, LP/J, NOD/ShiLtJ, PWK/PhJ, WSB/EiJ, Mus caroli, M. spretus, M. musculus, and M. poschiavinus. The mutation lies within a C-terminal cytoplasmic domain homologous with the TNFR 1-death domain and with an SH3 binding protein.

Rmcf^r

Allele Symbol: Rmcf^r

Allele Name	MCF resistant
Allele Type	Spontaneous
Allele Synonym(s)
Gene Symbol and Name	Rmcf, resistance to MCF virus
Gene Synonym(s)
Strain of Origin	multiple strains
Chromosome	5
General Note	This locus controls resistance and susceptibility of cells in tissue culture to infection by mink cell focus-forming murine leukemia viruses. The allele Rmcf^r determines resistance and occurs in strains DBA/1, DBA/2, and CBA/Ca; the allele Rmcf^s determines susceptibility and occurs in strains AKR/J, C57BL/6, BALB/c, CBA/J, NFS, NZB, 129/J, and many others. Heterozygotes are as resistant as the resistant parent or nearly so. Rmcf is different from and independent of Fv1, a locus that controls susceptibility to infection by ecotropic viruses. Rmcf is located on Chr 5 close to Hm near the centromeric end (J:7108). Rmcf^r protects (AKR x CBA/Ca)F1 and (AKR x DBA/2)F1 hybrids from development of spontaneous thymic lymphomas and reduces the incidence of MCF-induced thymic lymphomas (J:7175). It also reduces susceptibility of cells of Sxv^s/Sxv^r mice to exogenous xenotropic viruses (J:7951). In addition, in strains susceptible to Friend virus-induced erythroleukemia, a condition thought to be due to the replication of MCF virus, Rmcf^r increases resistance to the virus-induced erythroleukemia. It may cause resistance by coding for or regulating the production of an MCF-related envelope glycoprotein that blocks the receptor for MCF viruses (J:8074). This conclusion is reinforced by the findings of Buller et al. (J:8497), who showed that the Rmcf^r allele contains an endogenous MCF gp70 env gene and that the Rmcf^s allele, at least in some strains (C57BL/6, CBA/J, and A/WySn), contains a xenotropic gp70 env gene. Presumably the MCF gp70 inhibits exogenous MCF infection in vitro by a mechanism of viral interference.
Molecular Note	This locus controls resistance of cells to infection by mink cell focus-forming murine leukemia viruses. The dominant r (resistance) allele is found in strains DBA/1, DBA/2 and CBA/Ca.

Gpr84^del

Allele Symbol: Gpr84^del

Allele Name	deletion
Allele Type	Spontaneous (Null/Knockout)
Allele Synonym(s)
Gene Symbol and Name	Gpr84, G protein-coupled receptor 84
Gene Synonym(s)
Strain of Origin	multiple strains
Chromosome	15
Molecular Note	This spontaneously arising frameshift deletion is located in exon 2 at position 103308576 bp (NCBI Build 37) and results in a premature stop codon. The mutation is predicted to result in a truncated protein lacking the transmembrane domains 4-7. The inbred strains BDP/J, DBA/1J, DBA/2J, I/LnJ, FVB/NJ, LG/J, MRL/MpJ, NODShi/LtJ, NOR/LtJ, P/J, PL/J, SKHIN/Sprd, SJL/J, SM/J are homozygous for the deletion. The allele is segregating in the outbred stocks ICR and CD-1.

Cd5^a

Allele Symbol: Cd5^a

Allele Name	a variant
Allele Type	Spontaneous (Not Applicable)
Allele Synonym(s)	CD5.1; Ly-1.1
Gene Symbol and Name	Cd5, CD5 antigen
Gene Synonym(s)
Strain of Origin	multiple strains
Chromosome	19
Molecular Note	Sequence analysis of C3H/HeJ showed that this polymorphic variant has point mutations relative to the b variant that result in valine instead of isoleucine at amino acid 9, leucine instead of glutamine at amino acid 52, and isoleucine instead of phenylalanine at amino acid 71, all within the amino terminal scavenger receptor cysteine-rich D1 domain, in addition to 7 silent point mutations. This allele is found in many inbred strains including CBA/J, C3H and DBA substrains.

Cox7a2l^l

Allele Symbol: Cox7a2l^l

Allele Name	long
Allele Type	Not Applicable (Not Specified)
Allele Synonym(s)	SCAF1¹¹³
Gene Symbol and Name	Cox7a2l, cytochrome c oxidase subunit 7A2 like
Gene Synonym(s)
Strain of Origin	multiple strains
Chromosome	17
General Note	Querying the sequences of the Sanger Mouse Genomes Project reveals that the short allele with its 6 bp deletion exists in C57BL/6J, C57BL/10J, C57BL/6NJ, C58/J, BALB/cJ, C3H/HeH, 129S5/SvEvBrd, NZW/LacZ, and SEA/GnJ, but the long allele lacking the deletion exists in 129S1/SvImJ, A/J, AKR/J, BTBR T⁺ Itpr3^tf/J, BUB/BnJ, C3H/HeJ, C57BR/cdJ, C57L/J, CAST/EiJ, CBA/J, DBA/1J, DBA/2J, FVB/NJ, I/LnJ, KK/HiJ, LEWES/EiJ, LP/J, MOLF/EiJ, NOD/ShiLtJ, NZB/BlNJ, NZO/HlLtJ, PWK/PhJ, RF/J, SPRET/EiJ, ST/bJ, WSB/EiJ, ZALENDE/EiJ.
Molecular Note	This allele encodes the long isoform with 113 amino acids. It is found in 129S2/SvPasCrl, CBA/CaOlaHsd, Hsd:ICR, and NZB/OlaHsd.

B2m^a

Allele Symbol: B2m^a

Allele Name	a variant
Allele Type	Spontaneous (Not Applicable)
Allele Synonym(s)
Gene Symbol and Name	B2m, beta-2 microglobulin
Gene Synonym(s)
Strain of Origin	multiple strains
Chromosome	2
Molecular Note	The a variant is slightly slower running on SDS PAGE and was found to have an aspartic acid at amino acid position 85. This allele is found in A, BALB/c, LP and most other strains.

Disease/Phenotype

Disease Terms

Research Areas By Phenotype

This mouse can be used to support research in many areas including:

Genotype: Myo5a^d related

Mouse/Human Gene Homologs
- Griscelli Syndrome
Dermatology Research
- Color and White Spotting Defects

Genotype: Tyrp1^b related

Dermatology Research
- Color and White Spotting Defects
Mouse/Human Gene Homologs
- oculocutaneous albinism type III

Immunology, Inflammation and Autoimmunity Research
- Autoimmunity
  - collagen induced arthritis
- Inflammation
  - collagen induced arthritis
Research Tools
- General Purpose
Neurobiology Research
- Hearing Defects
  - Age related hearing loss
Sensorineural Research
- Hearing Defects
  - Age related hearing loss

Genotype: Cdh23^ahl related

Neurobiology Research
- Hearing Defects
  - Age related hearing loss
Sensorineural Research
- Hearing Defects
  - Age related hearing loss

Genotype: Hbb^d related

Hematological Research
- Hemoglobin Defects
Mouse/Human Gene Homologs
- thalassemia, beta

Mammalian Phenotype Terms by Genotype

The following phenotype relates to a compound genotype created using this strain

Genotype: Rmcf^r/Rmcf^r
DBA/1J

immune system phenotype

decreased susceptibility to Retroviridae infection
- resistant to N- and NB-tropic mink cell focus-forming (MCF) viruses

decreased susceptibility to viral infection
- resistant to N- and NB-tropic mink cell focus-forming (MCF) viruses

Phenotype Information

Festing Inbred Strain Characteristics: DBA

References

Doran AG; Wong K; Flint J; Adams DJ; Hunter KW; Keane TM. 2016. Deep genome sequencing and variation analysis of 13 inbred mouse strains defines candidate phenotypic alleles, private variation and homozygous truncating mutations. Genome Biol 17(1):167PubMed: 27480531 MGI: J:262923
Kato F; Nomura M; Nakamura K. 1996. Arthritis in mice induced by a single immunisation with collagen. Ann Rheum Dis 55(8):535-9PubMed: 8774181 MGI: J:109907
Lories RJ; Derese I; Luyten FP. 2005. Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis. J Clin Invest 115(6):1571-9PubMed: 15902307 MGI: J:109831
Lories RJ; Matthys P; de Vlam K; Derese I; Luyten FP. 2004. Ankylosing enthesitis, dactylitis, and onychoperiostitis in male DBA/1 mice: a model of psoriatic arthritis. Ann Rheum Dis 63(5):595-8PubMed: 15082495 MGI: J:109840
Matthys P; Lories RJ; De Klerck B; Heremans H; Luyten FP; Billiau A. 2003. Dependence on interferon-gamma for the spontaneous occurrence of arthritis in DBA/1 mice. Arthritis Rheum 48(10):2983-8PubMed: 14558106 MGI: J:106277
McIndoe RA; Bohlman B; Chi E; Schuster E; Lindhardt M; Hood L. 1999. Localization of non-Mhc collagen-induced arthritis susceptibility loci in DBA/1j mice. Proc Natl Acad Sci U S A 96(5):2210-4PubMed: 10051620 MGI: J:53356
Myers LK; Rosloniec EF; Cremer MA; Kang AH. 1997. Collagen-induced arthritis, an animal model of autoimmunity. Life Sci 61(19):1861-78PubMed: 9364191 MGI: J:109904
Paigen B; Morrow A; Brandon C; Mitchell D; Holmes P. 1985. Variation in susceptibility to atherosclerosis among inbred strains of mice. Atherosclerosis 57(1):65-73PubMed: 3841001 MGI: J:109950
Petkov PM; Cassell MA; Sargent EE; Donnelly CJ; Robinson P; Crew V; Asquith S; Haar RV; Wiles MV. 2004. Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse. Genomics 83(5):902-11PubMed: 15081119 MGI: J:89298
Timmermans S; Van Montagu M; Libert C. 2017. Complete overview of protein-inactivating sequence variations in 36 sequenced mouse inbred strains. Proc Natl Acad Sci U S A 114(34):9158-9163PubMed: 28784771 MGI: J:244295
Xie C; Sharma R; Wang H; Zhou XJ; Mohan C. 2004. Strain distribution pattern of susceptibility to immune-mediated nephritis. J Immunol 172(8):5047-55PubMed: 15067087 MGI: J:122988

Additional References

Courtenay JS; Dallman MJ; Dayan AD; Martin A; Mosedale B. 1980. Immunisation against heterologous type II collagen induces arthritis in mice. Nature 283(5748):666-8PubMed: 6153460 MGI: J:24763
Hartley JW; Yetter RA; Morse HC 3rd. 1983. A mouse gene on chromosome 5 that restricts infectivity of mink cell focus-forming recombinant murine leukemia viruses. J Exp Med 158(1):16-24PubMed: 6306133 MGI: J:7108
Heiniger HJ; Taylor BA; Hards EJ; Meier H. 1975. Heritability of the phytohemagglutinin responsiveness of lymphocytes and its relationship to leukemogenesis. Cancer Res 35(3):825-31PubMed: 163691 MGI: J:22608
International Nomenclature Committee. 1952. COMMITTEE on Standardized Nomenclature for Inbred Strains of Mice Cancer Res 12(8):602-13PubMed: 14945054 MGI: J:166288
Matsushima Y; Imai T; Watanabe O; Kawahara H; Ohne M; Takai H. 1984. Spontaneous calcified tongue lesions in DBA mice. Jikken Dobutsu 33(4):539-42PubMed: 6519193 MGI: J:166811
Michaelson J. 1983. Genetics of beta-2 microglobulin in the mouse. Immunogenetics 17(3):219-60PubMed: 6187676 MGI: J:7014
Taylor BA. 1972. Genetic relationships between inbred strains of mice. J Hered 63(2):83-6PubMed: 5031317 MGI: J:24288
Zheng QY; Johnson KR; Erway LC. 1999. Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses. Hear Res 130(1-2):94-107PubMed: 10320101 MGI: J:54812

Additional - a related

Additional - B2m^a related

Additional - Cd5^a related

Additional - Cdh23^ahl related

Additional - Cox7a2l^l related

Additional - Gpr84^del related

Additional - Hbb^d related

Additional - Myo5a^d related

Additional - P2rx7^rs48804829-T related

Additional - Rmcf^r related

Additional - Tyrp1^b related

Technical Support

CONTACT TECHNICAL SUPPORT

Genotyping Protocols
- Genotyping resources and troubleshooting
Inbred mouse strains are maintained through sibling (sister x brother) matings; no genotyping required.
Breeding Considerations

This strain is a good breeder.
- Additional Breeding and Husbandry Support
Mating System
- Sibling x Sibling
Appearance
- dilute brown
  Related Genotype: a/a Tyrp1^b/Tyrp1^b Myo5a^d/Myo5a^d
Citation
When using the DBA1 mouse strain in a publication, please include JAX stock #000670 in your Materials and Methods section.

Animal Health Reports

Facility Barrier Level Descriptions

EM05 (Maximum)

Pricing & Availability

Readily Available

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weeks

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Volume Pricing Program
Quantities: Volume pricing is automatically applied when a minimum quantity per strain for a shipment is reached
Sexes: Sexes of the same strain may be combined to reach minimum quantity levels to receive the volume pricing
Shipment: All shipping destinations qualify

Cryorecovery - Pricing

Service/Product	Description	Price
> >	Inbred, 1 pair minimum will be supplied

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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.

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Email: TechTran@jax.org

Also Known As:D1, DBA1, DBA, DBA/1

Genetic overview

Research Applications

Base Price

Volume Pricing Available!

Important Note

Detailed Description

Development

Selected References

a

Allele Symbol: a

Tyrp1b

Allele Symbol: Tyrp1b

Myo5ad

Allele Symbol: Myo5ad

Hbbd

Allele Symbol: Hbbd

Cdh23ahl

Allele Symbol: Cdh23ahl

P2rx7rs48804829-T

Allele Symbol: P2rx7rs48804829-T

Rmcfr

Allele Symbol: Rmcfr

Gpr84del

Allele Symbol: Gpr84del

Cd5a

Allele Symbol: Cd5a

Cox7a2ll

Allele Symbol: Cox7a2ll

B2ma

Allele Symbol: B2ma

Disease Terms

Research Areas By Phenotype

This mouse can be used to support research in many areas including:

Genotype: Myo5ad related

Genotype: Tyrp1b related

Genotype: Cdh23ahl related

Genotype: Hbbd related

Mammalian Phenotype Terms by Genotype

Genotype: Rmcfr/RmcfrDBA/1J

immune system phenotype

Phenotype Information

References

Additional References

Additional - a related

Additional - B2ma related

Additional - Cd5a related

Additional - Cdh23ahl related

Additional - Cox7a2ll related

Additional - Gpr84del related

Additional - Hbbd related

Additional - Myo5ad related

Additional - P2rx7rs48804829-T related

Additional - Rmcfr related

Additional - Tyrp1b related

Genotyping Protocols

Breeding Considerations

Mating System

Appearance

Citation

Animal Health Reports

Live Mouse

Volume Pricing Details

Cryorecovery - Pricing

Payment Terms and Conditions

The Jackson Laboratory's Genotype Promise

Terms Of Use

Licensing Information

Tyrp1^b

Allele Symbol: Tyrp1^b

Myo5a^d

Allele Symbol: Myo5a^d

Hbb^d

Allele Symbol: Hbb^d

Cdh23^ahl

Allele Symbol: Cdh23^ahl

P2rx7^rs48804829-T

Allele Symbol: P2rx7^rs48804829-T

Rmcf^r

Allele Symbol: Rmcf^r

Gpr84^del

Allele Symbol: Gpr84^del

Cd5^a

Allele Symbol: Cd5^a

Cox7a2l^l

Allele Symbol: Cox7a2l^l

B2m^a

Allele Symbol: B2m^a

Genotype: Myo5a^d related

Genotype: Tyrp1^b related

Genotype: Cdh23^ahl related

Genotype: Hbb^d related

Genotype: Rmcf^r/Rmcf^r
DBA/1J

Additional - B2m^a related

Additional - Cd5^a related

Additional - Cdh23^ahl related

Additional - Cox7a2l^l related

Additional - Gpr84^del related

Additional - Hbb^d related

Additional - Myo5a^d related

Additional - P2rx7^rs48804829-T related

Additional - Rmcf^r related

Additional - Tyrp1^b related