Mouse Strain Datasheet - 028548
Mouse Strain Datasheet - 028548
Exons 14 and 15 of the mouse Ret gene are flanked by loxP sites in this conditional mutant strain. Cre-mediated excision of the floxed region results in a knockout allele. A V805A mutation in exon 15 is functionally silent, but sensitizes the protein to chemical inhibition of its kinase activity.
David D. Ginty, Harvard Medical School
| Genetic Background | Generation |
|---|---|
|
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| Allele Type | Gene Symbol | Gene Name |
|---|---|---|
| Targeted (Conditional ready (e.g. floxed), No functional change) | Ret | ret proto-oncogene |
| Service | Genotype | Price |
|---|---|---|
| Heterozygous or wildtype for Ret<tm1.2Ddg> |
We will fulfill your order by providing at least two carriers for each strain ordered. The total number, sex, and genotypes provided will vary, although typically 8 or more animals are provided. Please check genotypes which will be recovered. While the genotypes of all animals produced will be communicated to you prior to scheduling shipment, the genotypes of animals provided may not reflect the mating scheme and genotypes described in the strain description. Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, then delivery time would increase to approximately 25 weeks. If we fail to produce animals of the correct genotype, you will not be charged. We cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.
Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation.
| Frozen Mouse Embryo | $2,595.00 per straw or vial |
