JAX Mouse Strain Datasheet - 007676

B6.129(Cg)-Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}/J

Stock No:: 007676 |; mT/mG

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Overview

Also Known As: mT/mG

mT/mG mice (Stock No. 007676) have the same allele as Stock No. 007576 but has a C57BL/6J congenic background. ROSA^mT/mG is a cell membrane-targeted, two-color fluorescent Cre-reporter allele. Prior to Cre recombination, cell membrane-localized tdTomato (mT) fluorescence expression is widespread in cells/tissues. Cre recombinase expressing cells (and future cell lineages derived from these cells) have cell membrane-localized EGFP (mG) fluorescence expression replacing the red fluorescence. ROSA^mT/mG mice (Stock No. 007576 and Stock No. 007676) function similarly to ROSA^nT-nG mice (Stock No. 023035 and Stock No. 023537), with ROSA^mT/mG directed to cell membrane and ROSA^nT-nG directed to nuclei.

Donating Investigator

IMR Colony, The Jackson Laboratory

Genetic overview

Genetic Background	Generation
	N11F8 (16-AUG-17)

Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}

Allele Type	Gene Symbol	Gene Name
Targeted (Conditional ready (e.g. floxed), Reporter)	Gt(ROSA)26Sor	gene trap ROSA 26, Philippe Soriano

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Research Applications

Neurobiology Research
Research Tools

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Base Price

Starting at:

$224.00 Domestic price for female 4-week

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Details

Detailed Description

Mice homozygous for this mT/mG mutation are viable and fertile. These mice possess loxP sites on either side of a membrane-targeted tdTomato (mT) cassette and express strong red fluorescence in all tissues and cell types examined. Tail or whole body epifluorescence is sufficient to identify mT/mG mice from wildtype mice. When bred to Cre recombinase expressing mice, the resulting offspring have the mT cassette deleted in the cre expressing tissue(s), allowing expression of the membrane-targeted EGFP (mG) cassette located just downstream. The donating investigator reports that the ACTB promoter allows stronger and persistent expression of the fluorescent proteins (especially in adult cells) compared to the endogenous Gt(ROSA) locus alone. This double-fluorescent system allows direct live visualization of both recombined and non-recombined cells at single cell resolution, offering an internal control for phenotypic analysis of Cre-induced mosaic mutants and providing a second marker for lineage tracing applications. In addition, the localization of fluorescent proteins to membrane structures outlines cell morphology and allows resolution of fine cellular processes. These mT/mG mice are useful as a Cre reporter strain; expressing red fluorescence prior to, and green fluorescence following, Cre-mediated recombination in widespread cell and tissue types.

In an attempt to offer alleles on well-characterized or multiple genetic backgrounds, alleles are frequently moved to a genetic background different from that on which an allele was first characterized. It should be noted that the phenotype could vary from that originally described. We will modify the strain description if necessary as published results become available.

Development

The mT/mG (membrane-Tomato/membrane-Green) targeting vector was designed with a CMV enhancer/chicken beta-actin core promoter (pCA) driving expression of a loxP-flanked, N-terminal membrane-tagged, tdTomato protein sequence followed by a polyadenylation signal (tdTomato is a non-oligomerizing DsRed variant with a 12 residue linker fusing two copies of the protein (tandem dimer)). Immediately distal to the second loxP site is an N-terminal membrane-tagged, enhanced green fluorescent protein (EGFP) sequence itself followed by a polyadenylation signal. An frt-flanked neo cassette was also located distal to the expression vector. This entire mT/mG construct was inserted into the Gt(ROSA)26Sor locus via electroporation of (129X1/SvJ x 129S1/Sv)F1-derived R1 embryonic stem (ES) cells. Correctly targeted ES cells were microinjected in C57BL/6J blastocysts. Chimeric progeny were bred to outbred CD-1 mice. The resulting mutant mice were interbred to generate homozygotes prior to arrival at The Jackson Laboratory (as Stock No. 007576). Upon arrival, some mice were backcrossed to C57BL/6J for at least five generations to generate this congenic strain (Stock No. 007676).

Expression Data

Expressed Gene	GFP, Green Fluorescent Protein,
Expressed Gene	RFP, Red Fluorescent Protein, coral
Site of Expression	Membrane-targeted tdTomato (mT) is expressed in all tissues and cell types examined. When bred to Cre recombinase expressing mice, the mT cassette is deleted in the cre expressing tissue(s), allowing expression of the membrane-targeted EGFP (mG).

Control Suggestions

000664 C57BL/6J

Additional Information

Considerations for Choosing Controls

Selected References

Muzumdar MD; Tasic B; Miyamichi K; Li L; Luo L. 2007. A global double-fluorescent Cre reporter mouse. Genesis 45(9):593-605. PubMed: 17868096 MGI: J:124702

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Genetics

Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}

Allele Symbol: Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}

Allele Name	targeted mutation 4, Liqun Luo
Allele Type	Targeted (Conditional ready (e.g. floxed), Reporter)
Allele Synonym(s)	Gt(ROSA26)^{ACTB-tdTomato-EGFP}; R26-X; R26-mR/mG; R26^TG; ROSA-R/G; ROSA-mT/mG; ROSA26-mTmG; ROSA^mT-mE; Rosa26^{flox-mTRed-Stop-flox-mGFP}; Rosa26^mTmG; Rosa26R^mTmG; Rosa26mTmG^flox; Rosa^mTmG; TomatoGFP+; mT/mG; mTmG; mTomato/mEGFP
Gene Symbol and Name	Gt(ROSA)26Sor, gene trap ROSA 26, Philippe Soriano
Gene Synonym(s)	AV258896; Gtrgeo26; Gtrgeo26; Gtrosa26; Gtrosa26; R26; ROSA26; SETD5-AS1; Thumpd3as1; beta geo; expressed sequence AV258896; gene trap ROSA 26; gene trap ROSA b-geo 26
Expressed Gene	GFP, Green Fluorescent Protein,
Expressed Gene	RFP, Red Fluorescent Protein, coral
Site of Expression	Membrane-targeted tdTomato (mT) is expressed in all tissues and cell types examined. When bred to Cre recombinase expressing mice, the mT cassette is deleted in the cre expressing tissue(s), allowing expression of the membrane-targeted EGFP (mG).
Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Chromosome	6
Molecular Note	The targeting vector was designed with a CMV enhancer/chicken beta-actin core promoter (pCA) driving expression of a loxP-flanked, N-terminal membrane-tagged, optimized DsRed fluorescent protein variant (called tandem-dimer-Tomato or tdTomato) sequence followed by a polyadenylation signal. Immediately distal to the second loxP site is an N-terminal membrane-tagged, enhanced green fluorescent protein (EGFP) sequence itself followed by a polyadenylation signal. An frt-flanked neo cassette was also located distal to the expression vector. Red fluorescence is detected in all tissues tested. When mice are bred to Cre expressing mice, the floxed region is excised in Cre-expressing tissue and this allows expression of the EGFP cassette.
Mutations Made By	Liqun Luo, Stanford University, HHMI

Disease/Phenotype

Disease Terms

Research Areas By Genotype

This mouse can be used to support research in many areas including:

Neurobiology Research
- Cre-lox System
  - loxP-flanked Sequences
  - loxP-flanked Sequences: Test/Reporter
Research Tools
- Cre-lox System
  - loxP-flanked Sequences
  - loxP-flanked Sequences: Test/Reporter
- Fluorescent Proteins
- Genetics Research
  - Mutagenesis and Transgenesis
  - Mutagenesis and Transgenesis: Cre-lox System
  - Tissue/Cell Markers
  - Tissue/Cell Markers: Cre-lox System
  - Tissue/Cell Markers: multiple

Genotype: GFP related

Research Tools
- Fluorescent Proteins

Mammalian Phenotype Terms by Genotype

The following phenotype information is associated with a similar, but not exact match to this JAX^® Mice strain

Genotype: Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}/Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}
involves: 129S1/Sv * 129X1/SvJ

normal phenotype

no abnormal phenotype detected
- mice are viable and fertile, with no observable adverse phenotypes

References

Muzumdar MD; Tasic B; Miyamichi K; Li L; Luo L. 2007. A global double-fluorescent Cre reporter mouse. Genesis 45(9):593-605. PubMed: 17868096 MGI: J:124702

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Chen H; Matsumoto K; Brockway BL; Rackley CR; Liang J; Lee JH; Jiang D; Noble PW; Randell SH; Kim CF; Stripp BR. 2012. Airway epithelial progenitors are region specific and show differential responses to bleomycin-induced lung injury. Stem Cells 30(9):1948-60. PubMed: 22696116 MGI: J:194655
Chen HI; Poduri A; Numi H; Kivela R; Saharinen P; McKay AS; Raftrey B; Churko J; Tian X; Zhou B; Wu JC; Alitalo K; Red-Horse K. 2014. VEGF-C and aortic cardiomyocytes guide coronary artery stem development. J Clin Invest 124(11):4899-914. PubMed: 25271623 MGI: J:217615
Chen HI; Sharma B; Akerberg BN; Numi HJ; Kivela R; Saharinen P; Aghajanian H; McKay AS; Bogard PE; Chang AH; Jacobs AH; Epstein JA; Stankunas K; Alitalo K; Red-Horse K. 2014. The sinus venosus contributes to coronary vasculature through VEGFC-stimulated angiogenesis. Development 141(23):4500-12. PubMed: 25377552 MGI: J:223081
Chen J; Tu X; Esen E; Joeng KS; Lin C; Arbeit JM; Ruegg MA; Hall MN; Ma L; Long F. 2014. WNT7B promotes bone formation in part through mTORC1. PLoS Genet 10(1):e1004145. PubMed: 24497849 MGI: J:208766
Chen PY; Qin L; Baeyens N; Li G; Afolabi T; Budatha M; Tellides G; Schwartz MA; Simons M. 2015. Endothelial-to-mesenchymal transition drives atherosclerosis progression. J Clin Invest 125(12):4514-28. PubMed: 26517696 MGI: J:229400
Chen PY; Qin L; Zhuang ZW; Tellides G; Lax I; Schlessinger J; Simons M. 2014. The docking protein FRS2alpha is a critical regulator of VEGF receptors signaling. Proc Natl Acad Sci U S A 111(15):5514-9. PubMed: 24706887 MGI: J:208873
Chen Q; Zhang H; Liu Y; Adams S; Eilken H; Stehling M; Corada M; Dejana E; Zhou B; Adams RH. 2016. Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells. Nat Commun 7:12422. PubMed: 27516371 MGI: J:236848
Chen WP; Liu YH; Ho YJ; Wu SM. 2015. Pharmacological inhibition of TGFbeta receptor improves Nkx2.5 cardiomyoblast-mediated regeneration. Cardiovasc Res 105(1):44-54. PubMed: 25362681 MGI: J:230304
Cheung KJ; Gabrielson E; Werb Z; Ewald AJ. 2013. Collective invasion in breast cancer requires a conserved basal epithelial program. Cell 155(7):1639-51. PubMed: 24332913 MGI: J:205494
Cheung KJ; Padmanaban V; Silvestri V; Schipper K; Cohen JD; Fairchild AN; Gorin MA; Verdone JE; Pienta KJ; Bader JS; Ewald AJ. 2016. Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters. Proc Natl Acad Sci U S A 113(7):E854-63. PubMed: 26831077 MGI: J:230438
Chi L; Ahmed A; Roy AR; Vuong S; Cahill LS; Caporiccio L; Sled JG; Caniggia I; Wilson MD; Delgado-Olguin P. 2017. G9a controls placental vascular maturation by activating the Notch Pathway. Development 144(11):1976-1987. PubMed: 28455378 MGI: J:241566
Chivukula RR; Shi G; Acharya A; Mills EW; Zeitels LR; Anandam JL; Abdelnaby AA; Balch GC; Mansour JC; Yopp AC; Maitra A; Mendell JT. 2014. An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell 157(5):1104-16. PubMed: 24855947 MGI: J:214382
Cho H; Zhao X; Hatori M; Yu RT; Barish GD; Lam MT; Chong LW; DiTacchio L; Atkins AR; Glass CK; Liddle C; Auwerx J; Downes M; Panda S; Evans RM. 2012. Regulation of circadian behaviour and metabolism by REV-ERB-alpha and REV-ERB-beta. Nature 485(7396):123-7. PubMed: 22460952 MGI: J:183855
Choi DC; Maguschak KA; Ye K; Jang SW; Myers KM; Ressler KJ. 2010. Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear. Proc Natl Acad Sci U S A 107(6):2675-80. PubMed: 20133801 MGI: J:157538
Choi N; Zhang B; Zhang L; Ittmann M; Xin L. 2012. Adult Murine Prostate Basal and Luminal Cells Are Self-Sustained Lineages that Can Both Serve as Targets for Prostate Cancer Initiation. Cancer Cell 21(2):253-65. PubMed: 22340597 MGI: J:181459
Choi YS; Zhang Y; Xu M; Yang Y; Ito M; Peng T; Cui Z; Nagy A; Hadjantonakis AK; Lang RA; Cotsarelis G; Andl T; Morrisey EE; Millar SE. 2013. Distinct Functions for Wnt/beta-Catenin in Hair Follicle Stem Cell Proliferation and Survival and Interfollicular Epidermal Homeostasis. Cell Stem Cell 13(6):720-33. PubMed: 24315444 MGI: J:204142
Chow K; Fessel JP; Kaoriihida-Stansbury; Schmidt EP; Gaskill C; Alvarez D; Graham B; Harrison DG; Wagner DH Jr; Nozik-Grayck E; West JD; Klemm DJ; Majka SM. 2013. Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling. Pulm Circ 3(1):31-49. PubMed: 23662173 MGI: J:233248
Chow SZ; Speck M; Yoganathan P; Nackiewicz D; Hansen AM; Ladefoged M; Rabe B; Rose-John S; Voshol PJ; Lynn FC; Herrera PL; Muller W; Ellingsgaard H; Ehses JA. 2014. Glycoprotein 130 receptor signaling mediates alpha-cell dysfunction in a rodent model of type 2 diabetes. Diabetes 63(9):2984-95. PubMed: 24812426 MGI: J:229838
Cognard N; Scerbo MJ; Obringer C; Yu X; Costa F; Haser E; Le D; Stoetzel C; Roux MJ; Moulin B; Dollfus H; Marion V. 2015. Comparing the Bbs10 complete knockout phenotype with a specific renal epithelial knockout one highlights the link between renal defects and systemic inactivation in mice. Cilia 4:10. PubMed: 26273430 MGI: J:227230
Comai G; Sambasivan R; Gopalakrishnan S; Tajbakhsh S. 2014. Variations in the efficiency of lineage marking and ablation confound distinctions between myogenic cell populations. Dev Cell 31(5):654-67. PubMed: 25490270 MGI: J:228101
Costello P; Sargent M; Maurice D; Esnault C; Foster K; Anjos-Afonso F; Treisman R. 2015. MRTF-SRF signaling is required for seeding of HSC/Ps in bone marrow during development. Blood 125(8):1244-55. PubMed: 25573994 MGI: J:221920
Coulson-Thomas VJ; Chang SH; Yeh LK; Coulson-Thomas YM; Yamaguchi Y; Esko J; Liu CY; Kao W. 2015. Loss of corneal epithelial heparan sulfate leads to corneal degeneration and impaired wound healing. Invest Ophthalmol Vis Sci 56(5):3004-14. PubMed: 26024086 MGI: J:230966
Coulson-Thomas VJ; Gesteira TF; Esko J; Kao W. 2014. Heparan sulfate regulates hair follicle and sebaceous gland morphogenesis and homeostasis. J Biol Chem 289(36):25211-26. PubMed: 25053416 MGI: J:216871
Crish J; Conti MA; Sakai T; Adelstein RS; Egelhoff TT. 2013. Keratin 5-Cre-driven excision of nonmuscle myosin IIA in early embryo trophectoderm leads to placenta defects and embryonic lethality. Dev Biol 382(1):136-48. PubMed: 23911870 MGI: J:202224
Crosswhite PL; Podsiadlowska JJ; Curtis CD; Gao S; Xia L; Srinivasan RS; Griffin CT. 2016. CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity. J Clin Invest 126(6):2254-66. PubMed: 27140400 MGI: J:237076
Croyle MJ; Lehman JM; O'Connor AK; Wong SY; Malarkey EB; Iribarne D; Dowdle WE; Schoeb TR; Verney ZM; Athar M; Michaud EJ; Reiter JF; Yoder BK. 2011. Role of epidermal primary cilia in the homeostasis of skin and hair follicles. Development 138(9):1675-85. PubMed: 21429982 MGI: J:171221
Daikoku T; Ogawa Y; Terakawa J; Ogawa A; DeFalco T; Dey SK. 2014. Lactoferrin-iCre: A New Mouse Line to Study Uterine Epithelial Gene Function. Endocrinology 155(7):2718-24. PubMed: 24823394 MGI: J:211105
Davis J; Piatigorsky J. 2011. Overexpression of Pax6 in mouse cornea directly alters corneal epithelial cells: changes in immune function, vascularization, and differentiation. Invest Ophthalmol Vis Sci 52(7):4158-68. PubMed: 21447684 MGI: J:181429
Davis SW; Keisler JL; Perez-Millan MI; Schade V; Camper SA. 2016. All Hormone-Producing Cell Types of the Pituitary Intermediate and Anterior Lobes Derive From Prop1-Expressing Progenitors. Endocrinology 157(4):1385-96. PubMed: 26812162 MGI: J:233898
De Bock K; Georgiadou M; Schoors S; Kuchnio A; Wong BW; Cantelmo AR; Quaegebeur A; Ghesquiere B; Cauwenberghs S; Eelen G; Phng LK; Betz I; Tembuyser B; Brepoels K; Welti J; Geudens I; Segura I; Cruys B; Bifari F; Decimo I; Blanco R; Wyns S; VangindertaelJ; Rocha S; Collins RT; Munck S; Daelemans D; Imamura H; Devlieger R; Rider M; Van Veldhoven PP; Schuit F; Bartrons R; Hofkens J; Fraisl P; Telang S; Deberardinis RJ; Schoonjans L; Vinckier S; Chesney J; Gerhardt H; Dewerchin M; Carmeliet P. 2013. Role of PFKFB3-Driven Glycolysis in Vessel Sprouting. Cell 154(3):651-63. PubMed: 23911327 MGI: J:200070
De Maria A; Bassnett S. 2015. Birc7: A Late Fiber Gene of the Crystalline Lens. Invest Ophthalmol Vis Sci 56(8):4823-34. PubMed: 26218911 MGI: J:230953
DeGraff DJ; Grabowska MM; Case TC; Yu X; Herrick MK; Hayward WJ; Strand DW; Cates JM; Hayward SW; Gao N; Walter MA; Buttyan R; Yi Y; Kaestner KH; Matusik RJ. 2014. FOXA1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype. Lab Invest 94(7):726-39. PubMed: 24840332 MGI: J:211363
Dellinger MT; Meadows SM; Wynne K; Cleaver O; Brekken RA. 2013. Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature. PLoS One 8(9):e74686. PubMed: 24023956 MGI: J:207561
Denny SK; Yang D; Chuang CH; Brady JJ; Lim JS; Gruner BM; Chiou SH; Schep AN; Baral J; Hamard C; Antoine M; Wislez M; Kong CS; Connolly AJ; Park KS; Sage J; Greenleaf WJ; Winslow MM. 2016. Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility. Cell 166(2):328-42. PubMed: 27374332 MGI: J:234641
Desai TJ; Brownfield DG; Krasnow MA. 2014. Alveolar progenitor and stem cells in lung development, renewal and cancer. Nature 507(7491):190-4. PubMed: 24499815 MGI: J:207468
Devi S; Wang Y; Chew WK; Lima R; A-Gonzalez N; Mattar CN; Chong SZ; Schlitzer A; Bakocevic N; Chew S; Keeble JL; Goh CC; Li JL; Evrard M; Malleret B; Larbi A; Renia L; Haniffa M; Tan SM; Chan JK; Balabanian K; Nagasawa T; Bachelerie F; Hidalgo A; GinhouxF; Kubes P; Ng LG. 2013. Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow. J Exp Med 210(11):2321-36. PubMed: 24081949 MGI: J:204051
Devine WP; Wythe JD; George M; Koshiba-Takeuchi K; Bruneau BG. 2014. Early patterning and specification of cardiac progenitors in gastrulating mesoderm. Elife 3:. PubMed: 25296024 MGI: J:232545
Dhawan S; Tschen SI; Zeng C; Guo T; Hebrok M; Matveyenko A; Bhushan A. 2015. DNA methylation directs functional maturation of pancreatic beta cells. J Clin Invest 125(7):2851-60. PubMed: 26098213 MGI: J:224543
Diersch S; Wirth M; Schneeweis C; Jors S; Geisler F; Siveke JT; Rad R; Schmid RM; Saur D; Rustgi AK; Reichert M; Schneider G. 2015. Kras induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells. Oncogene :. PubMed: 26592448 MGI: J:228015
Ding M; Carrao AC; Wagner RJ; Xie Y; Jin Y; Rzucidlo EM; Yu J; Li W; Tellides G; Hwa J; Aprahamian TR; Martin KA. 2012. Vascular smooth muscle cell-derived adiponectin: a paracrine regulator of contractile phenotype. J Mol Cell Cardiol 52(2):474-84. PubMed: 21952104 MGI: J:183565
Dinsmore C; Reiter JF. 2016. Endothelial primary cilia inhibit atherosclerosis. EMBO Rep 17(2):156-66. PubMed: 26769565 MGI: J:230502
Dorfman MD; Garcia-Rudaz C; Alderman Z; Kerr B; Lomniczi A; Dissen GA; Castellano JM; Garcia-Galiano D; Gaytan F; Xu B; Tena-Sempere M; Ojeda SR. 2014. Loss of Ntrk2/Kiss1r signaling in oocytes causes premature ovarian failure. Endocrinology 155(8):3098-111. PubMed: 24877631 MGI: J:214372
Dougherty SE; Hollimon JJ; McMeekin LJ; Bohannon AS; West AB; Lesort M; Hablitz JJ; Cowell RM. 2013. Hyperactivity and cortical disinhibition in mice with restricted expression of mutant huntingtin to parvalbumin-positive cells. Neurobiol Dis 62C:160-171. PubMed: 24121117 MGI: J:201960
Drelon C; Berthon A; Sahut-Barnola I; Mathieu M; Dumontet T; Rodriguez S; Batisse-Lignier M; Tabbal H; Tauveron I; Lefrancois-Martinez AM; Pointud JC; Gomez-Sanchez CE; Vainio S; Shan J; Sacco S; Schedl A; Stratakis CA; Martinez A; Val P. 2016. PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development. Nat Commun 7:12751. PubMed: 27624192 MGI: J:242183
Duval N; Daubas P; Bourcier de Carbon C; St Cloment C; Tinevez JY; Lopes M; Ribes V; Robert B. 2014. Msx1 and Msx2 act as essential activators of Atoh1 expression in the murine spinal cord. Development 141(8):1726-36. PubMed: 24715462 MGI: J:208848
Dy P; Wang W; Bhattaram P; Wang Q; Wang L; Ballock RT; Lefebvre V. 2012. Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytes. Dev Cell 22(3):597-609. PubMed: 22421045 MGI: J:183084
Ehling M; Adams S; Benedito R; Adams RH. 2013. Notch controls retinal blood vessel maturation and quiescence. Development 140(14):3051-61. PubMed: 23785053 MGI: J:198633
Engert S; Burtscher I; Kalali B; Gerhard M; Lickert H. 2013. The Sox17CreERT2 knock-in mouse line displays spatiotemporal activation of Cre recombinase in distinct Sox17 lineage progenitors. Genesis 51(11):793-802. PubMed: 24038996 MGI: J:204611
Epelman S; Lavine KJ; Beaudin AE; Sojka DK; Carrero JA; Calderon B; Brija T; Gautier EL; Ivanov S; Satpathy AT; Schilling JD; Schwendener R; Sergin I; Razani B; Forsberg EC; Yokoyama WM; Unanue ER; Colonna M; Randolph GJ; Mann DL. 2014. Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. Immunity 40(1):91-104. PubMed: 24439267 MGI: J:209372
Eser S; Reiff N; Messer M; Seidler B; Gottschalk K; Dobler M; Hieber M; Arbeiter A; Klein S; Kong B; Michalski CW; Schlitter AM; Esposito I; Kind AJ; Rad L; Schnieke AE; Baccarini M; Alessi DR; Rad R; Schmid RM; Schneider G; Saur D. 2013. Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer. Cancer Cell 23(3):406-20. PubMed: 23453624 MGI: J:197054
Espinoza-Lewis RA; Wang DZ. 2014. Generation of a Cre knock-in into the Myocardin locus to mark early cardiac and smooth muscle cell lineages. Genesis 52(10):879-87. PubMed: 25174608 MGI: J:217513
Evers B; Speksnijder EN; Schut E; Ciampricotti M; Smalley MJ; Derksen PW; Jonkers J; de Visser KE. 2010. A tissue reconstitution model to study cancer cell-intrinsic and -extrinsic factors in mammary tumourigenesis. J Pathol 220(1):34-44. PubMed: 19927317 MGI: J:155546
Fan F; Funk L; Lou X. 2016. Dynamin 1- and 3-Mediated Endocytosis Is Essential for the Development of a Large Central Synapse In Vivo. J Neurosci 36(22):6097-115. PubMed: 27251629 MGI: J:234091
Fan Q; Gu D; Liu H; Yang L; Zhang X; Yoder MC; Kaplan MH; Xie J. 2014. Defective TGF-beta signaling in bone marrow-derived cells prevents hedgehog-induced skin tumors. Cancer Res 74(2):471-83. PubMed: 24282281 MGI: J:206729
Fantauzzo KA; Soriano P. 2016. PDGFRbeta regulates craniofacial development through homodimers and functional heterodimers with PDGFRalpha. Genes Dev 30(21):2443-2458. PubMed: 27856617 MGI: J:237202
Faralli H; Wang C; Nakka K; Benyoucef A; Sebastian S; Zhuang L; Chu A; Palii CG; Liu C; Camellato B; Brand M; Ge K; Dilworth FJ. 2016. UTX demethylase activity is required for satellite cell-mediated muscle regeneration. J Clin Invest 126(4):1555-65. PubMed: 26999603 MGI: J:232700
Faria D; Rock JR; Romao AM; Schweda F; Bandulik S; Witzgall R; Schlatter E; Heitzmann D; Pavenstadt H; Herrmann E; Kunzelmann K; Schreiber R. 2014. The calcium-activated chloride channel Anoctamin 1 contributes to the regulation of renal function. Kidney Int 85(6):1369-81. PubMed: 24476694 MGI: J:210158
Farmer WT; Abrahamsson T; Chierzi S; Lui C; Zaelzer C; Jones EV; Bally BP; Chen GG; Theroux JF; Peng J; Bourque CW; Charron F; Ernst C; Sjostrom PJ; Murai KK. 2016. Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling. Science 351(6275):849-54. PubMed: 26912893 MGI: J:229525
Feil S; Fehrenbacher B; Lukowski R; Essmann F; Schulze-Osthoff K; Schaller M; Feil R. 2014. Transdifferentiation of vascular smooth muscle cells to macrophage-like cells during atherogenesis. Circ Res 115(7):662-7. PubMed: 25070003 MGI: J:234898
Ferone G; Song JY; Sutherland KD; Bhaskaran R; Monkhorst K; Lambooij JP; Proost N; Gargiulo G; Berns A. 2016. SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin. Cancer Cell 30(4):519-532. PubMed: 27728803 MGI: J:236715
Finnberg NK; Gokare P; Navaraj A; Lang Kuhs KA; Cerniglia G; Yagita H; Takeda K; Motoyama N; El-Deiry WS. 2016. Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity. Cancer Res 76(3):700-12. PubMed: 26609054 MGI: J:237555
Flodby P; Borok Z; Banfalvi A; Zhou B; Gao D; Minoo P; Ann DK; Morrisey EE; Crandall ED. 2010. Directed expression of Cre in alveolar epithelial type 1 cells. Am J Respir Cell Mol Biol 43(2):173-8. PubMed: 19767448 MGI: J:174124
Flodby P; Kim YH; Beard LL; Gao D; Ji Y; Kage H; Liebler JM; Minoo P; Kim KJ; Borok Z; Crandall ED. 2016. Knockout Mice Reveal a Major Role for Alveolar Epithelial Type I Cells in Alveolar Fluid Clearance. Am J Respir Cell Mol Biol :. PubMed: 27064541 MGI: J:233742
Flodby P; Liebler JM; Sunohara M; Castillo DR; McConnell AM; Krishnaveni MS; Banfalvi A; Li M; Stripp B; Zhou B; Crandall ED; Minoo P; Borok Z. 2017. Region-specific role for Pten in maintenance of epithelial phenotype and integrity. Am J Physiol Lung Cell Mol Physiol 312(1):L131-L142. PubMed: 27864284 MGI: J:238724
Foerster P; Daclin M; Asm S; Faucourt M; Boletta A; Genovesio A; Spassky N. 2017. mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis. Development 144(2):201-210. PubMed: 27993979 MGI: J:242328
Franco CA; Blanc J; Parlakian A; Blanco R; Aspalter IM; Kazakova N; Diguet N; Mylonas E; Gao-Li J; Vaahtokari A; Penard-Lacronique V; Fruttiger M; Rosewell I; Mericskay M; Gerhardt H; Li Z. 2013. SRF selectively controls tip cell invasive behavior in angiogenesis. Development 140(11):2321-33. PubMed: 23674601 MGI: J:198683
Frank DB; Peng T; Zepp JA; Snitow M; Vincent TL; Penkala IJ; Cui Z; Herriges MJ; Morley MP; Zhou S; Lu MM; Morrisey EE. 2016. Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation. Cell Rep 17(9):2312-2325. PubMed: 27880906 MGI: J:241237
Frank DU; Carter KL; Thomas KR; Burr RM; Bakker ML; Coetzee WA; Tristani-Firouzi M; Bamshad MJ; Christoffels VM; Moon AM. 2011. Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis. Proc Natl Acad Sci U S A :. PubMed: 22203979 MGI: J:179977
Fre S; Hannezo E; Sale S; Huyghe M; Lafkas D; Kissel H; Louvi A; Greve J; Louvard D; Artavanis-Tsakonas S. 2011. Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice. PLoS One 6(10):e25785. PubMed: 21991352 MGI: J:179632
Freedman BD; Kempna PB; Carlone DL; Shah MS; Guagliardo NA; Barrett PQ; Gomez-Sanchez CE; Majzoub JA; Breault DT. 2013. Adrenocortical zonation results from lineage conversion of differentiated zona glomerulosa cells. Dev Cell 26(6):666-73. PubMed: 24035414 MGI: J:204614
Gandhi D; Molotkov A; Batourina E; Schneider K; Dan H; Reiley M; Laufer E; Metzger D; Liang F; Liao Y; Sun TT; Aronow B; Rosen R; Mauney J; Adam R; Rosselot C; Van Batavia J; McMahon A; McMahon J; Guo JJ; Mendelsohn C. 2013. Retinoid signaling in progenitors controls specification and regeneration of the urothelium. Dev Cell 26(5):469-82. PubMed: 23993789 MGI: J:204539
Garcia TX; Farmaha JK; Kow S; Hofmann MC. 2014. RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche. Development 141(23):4468-78. PubMed: 25406395 MGI: J:217593
Gaudreau MC; Heyd F; Bastien R; Wilhelm B; Moroy T. 2012. Alternative splicing controlled by heterogeneous nuclear ribonucleoprotein L regulates development, proliferation, and migration of thymic pre-T cells. J Immunol 188(11):5377-88. PubMed: 22523384 MGI: J:188749
George L; Chaverra M; Wolfe L; Thorne J; Close-Davis M; Eibs A; Riojas V; Grindeland A; Orr M; Carlson GA; Lefcort F. 2013. Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons. Proc Natl Acad Sci U S A 110(46):18698-703. PubMed: 24173031 MGI: J:202989
Gerl K; Miquerol L; Todorov VT; Hugo CP; Adams RH; Kurtz A; Kurt B. 2015. Inducible glomerular erythropoietin production in the adult kidney. Kidney Int 88(6):1345-1355. PubMed: 26398496 MGI: J:236849
Ghosh S; Lau H; Simons BW; Powell JD; Meyers DJ; De Marzo AM; Berman DM; Lotan TL. 2011. PI3K/mTOR signaling regulates prostatic branching morphogenesis. Dev Biol 360(2):329-42. PubMed: 22015718 MGI: J:178714
Ghosh S; Varela L; Sood A; Park BH; Lotan TL. 2013. mTOR Signaling Feedback Modulates Mammary Epithelial Differentiation and Restrains Invasion Downstream of PTEN Loss. Cancer Res 73(16):5218-31. PubMed: 23774212 MGI: J:200612
Glasco DM; Pike W; Qu Y; Reustle L; Misra K; Di Bonito M; Studer M; Fritzsch B; Goffinet AM; Tissir F; Chandrasekhar A. 2016. The atypical cadherin Celsr1 functions non-cell autonomously to block rostral migration of facial branchiomotor neurons in mice. Dev Biol 417(1):40-9. PubMed: 27395006 MGI: J:235628
Godel M; Hartleben B; Herbach N; Liu S; Zschiedrich S; Lu S; Debreczeni-Mor A; Lindenmeyer MT; Rastaldi MP; Hartleben G; Wiech T; Fornoni A; Nelson RG; Kretzler M; Wanke R; Pavenstadt H; Kerjaschki D; Cohen CD; Hall MN; Ruegg MA; Inoki K; Walz G; Huber TB. 2011. Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J Clin Invest 121(6):2197-209. PubMed: 21606591 MGI: J:174021
Gopalakrishnan S; Comai G; Sambasivan R; Francou A; Kelly RG; Tajbakhsh S. 2015. A Cranial Mesoderm Origin for Esophagus Striated Muscles. Dev Cell 34(6):694-704. PubMed: 26387456 MGI: J:225351
Grahammer F; Nesterov V; Ahmed A; Steinhardt F; Sandner L; Arnold F; Cordts T; Negrea S; Bertog M; Ruegg MA; Hall MN; Walz G; Korbmacher C; Artunc F; Huber TB. 2016. mTORC2 critically regulates renal potassium handling. J Clin Invest 126(5):1773-82. PubMed: 27043284 MGI: J:234958
Greder LV; Gupta S; Li S; Abedin MJ; Sajini A; Segal Y; Slack JM; Dutton JR. 2012. Analysis of endogenous Oct4 activation during induced pluripotent stem cell reprogramming using an inducible Oct4 lineage label. Stem Cells 30(11):2596-601. PubMed: 22948941 MGI: J:194647
Green S; Trejo CL; McMahon M. 2015. PIK3CAH1047R Accelerates and Enhances KRASG12D-Driven Lung Tumorigenesis. Cancer Res 75(24):5378-91. PubMed: 26567140 MGI: J:227253
Greenbaum AM; Revollo LD; Woloszynek JR; Civitelli R; Link DC. 2012. N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells. Blood 120(2):295-302. PubMed: 22323481 MGI: J:188098
Greif DM; Kumar M; Lighthouse JK; Hum J; An A; Ding L; Red-Horse K; Espinoza FH; Olson L; Offermanns S; Krasnow MA. 2012. Radial construction of an arterial wall. Dev Cell 23(3):482-93. PubMed: 22975322 MGI: J:189012
Greulich F; Farin HF; Schuster-Gossler K; Kispert A. 2012. Tbx18 function in epicardial development. Cardiovasc Res 96(3):476-83. PubMed: 22926762 MGI: J:210076
Grieskamp T; Rudat C; Ludtke TH; Norden J; Kispert A. 2011. Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res 108(7):813-23. PubMed: 21252157 MGI: J:183603
Grisanti L; Clavel C; Cai X; Rezza A; Tsai SY; Sennett R; Mumau M; Cai CL; Rendl M. 2013. Tbx18 targets dermal condensates for labeling, isolation, and gene ablation during embryonic hair follicle formation. J Invest Dermatol 133(2):344-53. PubMed: 22992803 MGI: J:196480
Grisanti L; Rezza A; Clavel C; Sennett R; Rendl M. 2013. Enpp2/Autotaxin in dermal papilla precursors is dispensable for hair follicle morphogenesis. J Invest Dermatol 133(10):2332-9. PubMed: 23677168 MGI: J:202516
Grosse AS; Pressprich MF; Curley LB; Hamilton KL; Margolis B; Hildebrand JD; Gumucio DL. 2011. Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis. Development 138(20):4423-32. PubMed: 21880782 MGI: J:178336
Grutzendler J; Murikinati S; Hiner B; Ji L; Lam CK; Yoo T; Gupta S; Hafler BP; Adelman RA; Yuan P; Rodriguez G. 2014. Angiophagy prevents early embolus washout but recanalizes microvessels through embolus extravasation. Sci Transl Med 6(226):226ra31. PubMed: 24598589 MGI: J:213666
Guidotti LG; Inverso D; Sironi L; Di Lucia P; Fioravanti J; Ganzer L; Fiocchi A; Vacca M; Aiolfi R; Sammicheli S; Mainetti M; Cataudella T; Raimondi A; Gonzalez-Aseguinolaza G; Protzer U; Ruggeri ZM; Chisari FV; Isogawa M; Sitia G; Iannacone M. 2015. Immunosurveillance of the liver by intravascular effector CD8(+) T cells. Cell 161(3):486-500. PubMed: 25892224 MGI: J:223134
Guo C; Sun Y; Guo C; MacDonald BT; Borer JG; Li X. 2014. Dkk1 in the peri-cloaca mesenchyme regulates formation of anorectal and genitourinary tracts. Dev Biol 385(1):41-51. PubMed: 24479159 MGI: J:241980
Hackl MJ; Burford JL; Villanueva K; Lam L; Susztak K; Schermer B; Benzing T; Peti-Peterdi J. 2013. Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags. Nat Med 19(12):1661-6. PubMed: 24270544 MGI: J:206843
Hampton HR; Bailey J; Tomura M; Brink R; Chtanova T. 2015. Microbe-dependent lymphatic migration of neutrophils modulates lymphocyte proliferation in lymph nodes. Nat Commun 6:7139. PubMed: 25972253 MGI: J:224874
Hann S; Kvenvold L; Newby BN; Hong M; Warman ML. 2013. A Wisp3 Cre-knockin allele produces efficient recombination in spermatocytes during early prophase of meiosis I. PLoS One 8(9):e75116. PubMed: 24040393 MGI: J:201718
Hao W; Decker Y; Schnoder L; Schottek A; Li D; Menger MD; Fassbender K; Liu Y. 2016. Deficiency of IkappaB Kinase beta in Myeloid Cells Reduces Severity of Experimental Autoimmune Encephalomyelitis. Am J Pathol 186(5):1245-57. PubMed: 26968344 MGI: J:232052
Hartman BH; Reh TA; Bermingham-McDonogh O. 2010. Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear. Proc Natl Acad Sci U S A 107(36):15792-7. PubMed: 20798046 MGI: J:164376
Hasegawa D; Calvo V; Avivar-Valderas A; Lade A; Chou HI; Lee YA; Farias EF; Aguirre-Ghiso JA; Friedman SL. 2015. Epithelial Xbp1 is required for cellular proliferation and differentiation during mammary gland development. Mol Cell Biol 35(9):1543-56. PubMed: 25713103 MGI: J:224417
Hashimoto D; Chow A; Noizat C; Teo P; Beasley MB; Leboeuf M; Becker CD; See P; Price J; Lucas D; Greter M; Mortha A; Boyer SW; Forsberg EC; Tanaka M; van Rooijen N; Garcia-Sastre A; Stanley ER; Ginhoux F; Frenette PS; Merad M. 2013. Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity 38(4):792-804. PubMed: 23601688 MGI: J:196958
Hashimoto S; Chen H; Que J; Brockway BL; Drake JA; Snyder JC; Randell SH; Stripp BR. 2012. beta-Catenin-SOX2 signaling regulates the fate of developing airway epithelium. J Cell Sci 125(Pt 4):932-42. PubMed: 22421361 MGI: J:197815
Hayakawa Y; Sakitani K; Konishi M; Asfaha S; Niikura R; Tomita H; Renz BW; Tailor Y; Macchini M; Middelhoff M; Jiang Z; Tanaka T; Dubeykovskaya ZA; Kim W; Chen X; Urbanska AM; Nagar K; Westphalen CB; Quante M; Lin CS; Gershon MD; Hara A; Zhao CM; Chen D; Worthley DL; Koike K; Wang TC. 2017. Nerve Growth Factor Promotes Gastric Tumorigenesis through Aberrant Cholinergic Signaling. Cancer Cell 31(1):21-34. PubMed: 27989802 MGI: J:238420
Hayashi T; Lombaert IM; Hauser BR; Patel VN; Hoffman MP. 2017. Exosomal MicroRNA Transport from Salivary Mesenchyme Regulates Epithelial Progenitor Expansion during Organogenesis. Dev Cell 40(1):95-103. PubMed: 28041903 MGI: J:238412
He Y; Zhang H; Yu L; Gunel M; Boggon TJ; Chen H; Min W. 2010. Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development. Sci Signal 3(116):ra26. PubMed: 20371769 MGI: J:171969
He Y; Zhang H; Yung A; Villeda SA; Jaeger PA; Olayiwola O; Fainberg N; Wyss-Coray T. 2014. ALK5-dependent TGF-beta signaling is a major determinant of late-stage adult neurogenesis. Nat Neurosci 17(7):943-52. PubMed: 24859199 MGI: J:213201
Headley MB; Bins A; Nip A; Roberts EW; Looney MR; Gerard A; Krummel MF. 2016. Visualization of immediate immune responses to pioneer metastatic cells in the lung. Nature 531(7595):513-7. PubMed: 26982733 MGI: J:232712
Heallen T; Morikawa Y; Leach J; Tao G; Willerson JT; Johnson RL; Martin JF. 2013. Hippo signaling impedes adult heart regeneration. Development 140(23):4683-90. PubMed: 24255096 MGI: J:206316
Heffner CS; Herbert Pratt C; Babiuk RP; Sharma Y; Rockwood SF; Donahue LR; Eppig JT; Murray SA. 2012. Supporting conditional mouse mutagenesis with a comprehensive cre characterization resource. Nat Commun 3:1218. PubMed: 23169059 MGI: J:226227
Heldt SA; Ressler KJ. 2009. The Use of Lentiviral Vectors and Cre/loxP to Investigate the Function of Genes in Complex Behaviors. Front Mol Neurosci 2:22. PubMed: 20011219 MGI: J:210657
Henderson NC; Arnold TD; Katamura Y; Giacomini MM; Rodriguez JD; McCarty JH; Pellicoro A; Raschperger E; Betsholtz C; Ruminski PG; Griggs DW; Prinsen MJ; Maher JJ; Iredale JP; Lacy-Hulbert A; Adams RH; Sheppard D. 2013. Targeting of alphav integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nat Med 19(12):1617-24. PubMed: 24216753 MGI: J:205525
Hendley AM; Provost E; Bailey JM; Wang YJ; Cleveland MH; Blake D; Bittman RW; Roeser JC; Maitra A; Reynolds AB; Leach SD. 2015. p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas. Dev Biol 399(1):41-53. PubMed: 25523391 MGI: J:219824
Hendley AM; Wang YJ; Polireddy K; Alsina J; Ahmed I; Lafaro KJ; Zhang H; Roy N; Savidge SG; Cao Y; Hebrok M; Maitra A; Reynolds AB; Goggins M; Younes M; Iacobuzio-Donahue CA; Leach SD; Bailey JM. 2016. p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia. Cancer Res 76(11):3351-63. PubMed: 27032419 MGI: J:231905
Hennig AK; Peng GH; Chen S. 2013. Transcription coactivators p300 and CBP are necessary for photoreceptor-specific chromatin organization and gene expression. PLoS One 8(7):e69721. PubMed: 23922782 MGI: J:204696
Hindi SM; Kumar A. 2016. TRAF6 regulates satellite stem cell self-renewal and function during regenerative myogenesis. J Clin Invest 126(1):151-68. PubMed: 26619121 MGI: J:229818
Hindi SM; Shin J; Ogura Y; Li H; Kumar A. 2013. Matrix metalloproteinase-9 inhibition improves proliferation and engraftment of myogenic cells in dystrophic muscle of mdx mice. PLoS One 8(8):e72121. PubMed: 23977226 MGI: J:225186
Hirai M; Arita Y; McGlade CJ; Lee KF; Chen J; Evans SM. 2017. Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. J Clin Invest 127(2):569-582. PubMed: 28067668 MGI: J:239830
Hirai M; Chen J; Evans SM. 2016. Generation and Characterization of a Tissue-Specific Centrosome Indicator Mouse Line. Genesis 54(5):286-96. PubMed: 26990996 MGI: J:234834
Ho YS; Tsai WH; Lin FC; Huang WP; Lin LC; Wu SM; Liu YR; Chen WP. 2016. Cardioprotective Actions of TGFbetaRI Inhibition Through Stimulating Autocrine/Paracrine of Survivin and Inhibiting Wnt in Cardiac Progenitors. Stem Cells 34(2):445-55. PubMed: 26418219 MGI: J:233089
Hoch RV; Clarke JA; Rubenstein JL. 2015. Fgf signaling controls the telencephalic distribution of Fgf-expressing progenitors generated in the rostral patterning center. Neural Dev 10:8. PubMed: 25889070 MGI: J:222259
Hohne M; Ising C; Hagmann H; Volker LA; Brahler S; Schermer B; Brinkkoetter PT; Benzing T. 2013. Light microscopic visualization of podocyte ultrastructure demonstrates oscillating glomerular contractions. Am J Pathol 182(2):332-8. PubMed: 23246153 MGI: J:193169
Hong KY; Bae H; Park I; Park DY; Kim KH; Kubota Y; Cho ES; Kim H; Adams RH; Yoo OJ; Koh GY. 2015. Perilipin+ embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion. Development 142(15):2623-32. PubMed: 26243869 MGI: J:239792
Hu H; Li J; Gagen CS; Gray NW; Zhang Z; Qi Y; Zhang P. 2011. Conditional knockout of protein O-mannosyltransferase 2 reveals tissue-specific roles of O-mannosyl glycosylation in brain development. J Comp Neurol 519(7):1320-37. PubMed: 21452199 MGI: J:179356
Hu J; Verzi MP; Robinson AS; Tang PL; Hua LL; Xu SM; Kwok PY; Black BL. 2015. Endothelin signaling activates Mef2c expression in the neural crest through a MEF2C-dependent positive-feedback transcriptional pathway. Development 142(16):2775-80. PubMed: 26160899 MGI: J:224213
Huang X; Liu J; Ketova T; Fleming JT; Grover VK; Cooper MK; Litingtung Y; Chiang C. 2010. Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development. Proc Natl Acad Sci U S A 107(18):8422-7. PubMed: 20400693 MGI: J:160335
Huang ZP; Young Seok H; Zhou B; Chen J; Chen JF; Tao Y; Pu WT; Wang DZ. 2012. CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circ Res 110(6):818-30. PubMed: 22343712 MGI: J:212665
Huebner RJ; Lechler T; Ewald AJ. 2014. Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells. Development 141(5):1085-94. PubMed: 24550116 MGI: J:234159
Huebner RJ; Neumann NM; Ewald AJ. 2016. Mammary epithelial tubes elongate through MAPK-dependent coordination of cell migration. Development 143(6):983-93. PubMed: 26839364 MGI: J:234157
Hung CM; Calejman CM; Sanchez-Gurmaches J; Li H; Clish CB; Hettmer S; Wagers AJ; Guertin DA. 2014. Rictor/mTORC2 Loss in the Myf5 Lineage Reprograms Brown Fat Metabolism and Protects Mice against Obesity and Metabolic Disease. Cell Rep 8(1):256-71. PubMed: 25001283 MGI: J:212069
Ichise T; Yoshida N; Ichise H. 2014. FGF2-induced Ras-MAPK signalling maintains lymphatic endothelial cell identity by upregulating endothelial-cell-specific gene expression and suppressing TGFbeta signalling through Smad2. J Cell Sci 127(Pt 4):845-57. PubMed: 24357720 MGI: J:212356
Ichise T; Yoshida N; Ichise H. 2010. H-, N- and Kras cooperatively regulate lymphatic vessel growth by modulating VEGFR3 expression in lymphatic endothelial cells in mice. Development 137(6):1003-13. PubMed: 20179099 MGI: J:159024
Iverson SV; Comstock KM; Kundert JA; Schmidt EE. 2011. Contributions of new hepatocyte lineages to liver growth, maintenance, and regeneration in mice. Hepatology 54(2):655-63. PubMed: 21538442 MGI: J:234606
Jacobs DT; Silva LM; Allard BA; Schonfeld MP; Chatterjee A; Talbott GC; Beier DR; Tran PV. 2016. Dysfunction of intraflagellar transport-A causes hyperphagia-induced obesity and metabolic syndrome. Dis Model Mech 9(7):789-98. PubMed: 27482817 MGI: J:234171
Jain R; Barkauskas CE; Takeda N; Bowie EJ; Aghajanian H; Wang Q; Padmanabhan A; Manderfield LJ; Gupta M; Li D; Li L; Trivedi CM; Hogan BL; Epstein JA. 2015. Plasticity of Hopx(+) type I alveolar cells to regenerate type II cells in the lung. Nat Commun 6:6727. PubMed: 25865356 MGI: J:222725
Jan TA; Chai R; Sayyid ZN; van Amerongen R; Xia A; Wang T; Sinkkonen ST; Zeng YA; Levin JR; Heller S; Nusse R; Cheng AG. 2013. Tympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells. Development 140(6):1196-206. PubMed: 23444352 MGI: J:194845
Jarrar W; Dias JM; Ericson J; Arnold HH; Holz A. 2015. Nkx2.2 and Nkx2.9 are the key regulators to determine cell fate of branchial and visceral motor neurons in caudal hindbrain. PLoS One 10(4):e0124408. PubMed: 25919494 MGI: J:235102
Jarrar W; Vauti F; Arnold HH; Holz A. 2015. Generation of a Nkx2.2(Cre) knock-in mouse line: Analysis of cell lineages in the central nervous system. Differentiation 89(3-4):70-6. PubMed: 25840610 MGI: J:222414
Jeffery E; Berry R; Church CD; Yu S; Shook BA; Horsley V; Rosen ED; Rodeheffer MS. 2014. Characterization of Cre recombinase models for the study of adipose tissue. Adipocyte 3(3):206-11. PubMed: 25068087 MGI: J:234899
Jeffery E; Church CD; Holtrup B; Colman L; Rodeheffer MS. 2015. Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity. Nat Cell Biol 17(4):376-85. PubMed: 25730471 MGI: J:220886
Jia S; Ivanov A; Blasevic D; Muller T; Purfurst B; Sun W; Chen W; Poy MN; Rajewsky N; Birchmeier C. 2015. Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic beta-cell function. EMBO J 34(10):1417-33. PubMed: 25828096 MGI: J:221186
Jiang X; Ma T; Zhang Y; Zhang H; Yin S; Zheng W; Wang L; Wang Z; Khan M; Sheikh SW; Bukhari I; Iqbal F; Cooke HJ; Shi Q. 2015. Specific deletion of Cdh2 in Sertoli cells leads to altered meiotic progression and subfertility of mice. Biol Reprod 92(3):79. PubMed: 25631347 MGI: J:221812
Johansson E; Andersson L; Ornros J; Carlsson T; Ingeson-Carlsson C; Liang S; Dahlberg J; Jansson S; Parrillo L; Zoppoli P; Barila GO; Altschuler DL; Padula D; Lickert H; Fagman H; Nilsson M. 2015. Revising the embryonic origin of thyroid C cells in mice and humans. Development 142(20):3519-28. PubMed: 26395490 MGI: J:239771
Kadzik RS; Cohen ED; Morley MP; Stewart KM; Lu MM; Morrisey EE. 2014. Wnt ligand/Frizzled 2 receptor signaling regulates tube shape and branch-point formation in the lung through control of epithelial cell shape. Proc Natl Acad Sci U S A 111(34):12444-9. PubMed: 25114215 MGI: J:213915
Kaftanovskaya EM; Lopez C; Ferguson L; Myhr C; Agoulnik AI. 2015. Genetic ablation of androgen receptor signaling in fetal Leydig cell lineage affects Leydig cell functions in adult testis. FASEB J 29(6):2327-37. PubMed: 25713029 MGI: J:223361
Kaltcheva MM; Anderson MJ; Harfe BD; Lewandoski M. 2016. BMPs are direct triggers of interdigital programmed cell death. Dev Biol 411(2):266-76. PubMed: 26826495 MGI: J:231462
Kaminski MM; Tosic J; Kresbach C; Engel H; Klockenbusch J; Muller AL; Pichler R; Grahammer F; Kretz O; Huber TB; Walz G; Arnold SJ; Lienkamp SS. 2016. Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors. Nat Cell Biol 18(12):1269-1280. PubMed: 27820600 MGI: J:238554
Kang SH; Fukaya M; Yang JK; Rothstein JD; Bergles DE. 2010. NG2+ CNS glial progenitors remain committed to the oligodendrocyte lineage in postnatal life and following neurodegeneration. Neuron 68(4):668-81. PubMed: 21092857 MGI: J:167748
Kang SH; Li Y; Fukaya M; Lorenzini I; Cleveland DW; Ostrow LW; Rothstein JD; Bergles DE. 2013. Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis. Nat Neurosci 16(5):571-9. PubMed: 23542689 MGI: J:197615
Kanisicak O; Khalil H; Ivey MJ; Karch J; Maliken BD; Correll RN; Brody MJ; J Lin SC; Aronow BJ; Tallquist MD; Molkentin JD. 2016. Genetic lineage tracing defines myofibroblast origin and function in the injured heart. Nat Commun 7:12260. PubMed: 27447449 MGI: J:241168
Kapitsinou PP; Sano H; Michael M; Kobayashi H; Davidoff O; Bian A; Yao B; Zhang MZ; Harris RC; Duffy KJ; Erickson-Miller CL; Sutton TA; Haase VH. 2014. Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury. J Clin Invest 124(6):2396-409. PubMed: 24789906 MGI: J:212930
Karner CM; Long F; Solnica-Krezel L; Monk KR; Gray RS. 2015. Gpr126/Adgrg6 deletion in cartilage models idiopathic scoliosis and pectus excavatum in mice. Hum Mol Genet 24(15):4365-73. PubMed: 25954032 MGI: J:224002
Kautschitsch S; Andersen L; Hammerschmid S; Rulicke T. 2014. Rapid identification of targeted transgene integrations in ES cells by fluorescence detection. Transgenic Res 23(3):469-75. PubMed: 24482264 MGI: J:213521
Keefe AC; Lawson JA; Flygare SD; Fox ZD; Colasanto MP; Mathew SJ; Yandell M; Kardon G. 2015. Muscle stem cells contribute to myofibres in sedentary adult mice. Nat Commun 6:7087. PubMed: 25971691 MGI: J:224875
Kierdorf K; Erny D; Goldmann T; Sander V; Schulz C; Perdiguero EG; Wieghofer P; Heinrich A; Riemke P; Holscher C; Muller DN; Luckow B; Brocker T; Debowski K; Fritz G; Opdenakker G; Diefenbach A; Biber K; Heikenwalder M; Geissmann F; Rosenbauer F; Prinz M. 2013. Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways. Nat Neurosci 16(3):273-80. PubMed: 23334579 MGI: J:197476
Kim S; Lewis AE; Singh V; Ma X; Adelstein R; Bush JO. 2015. Convergence and extrusion are required for normal fusion of the mammalian secondary palate. PLoS Biol 13(4):e1002122. PubMed: 25848986 MGI: J:222409
Kim SC; Kellett T; Wang S; Nishi M; Nagre N; Zhou B; Flodby P; Shilo K; Ghadiali SN; Takeshima H; Hubmayr RD; Zhao X. 2014. TRIM72 is required for effective repair of alveolar epithelial cell wounding. Am J Physiol Lung Cell Mol Physiol 307(6):L449-59. PubMed: 25106429 MGI: J:222068
Kim SY; Cordeiro MH; Serna VA; Ebbert K; Butler LM; Sinha S; Mills AA; Woodruff TK; Kurita T. 2013. Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling network. Cell Death Differ 20(8):987-97. PubMed: 23598363 MGI: J:228629
Kimura W; Xiao F; Canseco DC; Muralidhar S; Thet S; Zhang HM; Abderrahman Y; Chen R; Garcia JA; Shelton JM; Richardson JA; Ashour AM; Asaithamby A; Liang H; Xing C; Lu Z; Zhang CC; Sadek HA. 2015. Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart. Nature 523(7559):226-30. PubMed: 26098368 MGI: J:224072
King P; Paul A; Laufer E. 2009. Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages. Proc Natl Acad Sci U S A 106(50):21185-90. PubMed: 19955443 MGI: J:155826
Kisseleva T; Cong M; Paik Y; Scholten D; Jiang C; Benner C; Iwaisako K; Moore-Morris T; Scott B; Tsukamoto H; Evans SM; Dillmann W; Glass CK; Brenner DA. 2012. Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci U S A 109(24):9448-53. PubMed: 22566629 MGI: J:185556
Kizhatil K; Ryan M; Marchant JK; Henrich S; John SW. 2014. Schlemm's canal is a unique vessel with a combination of blood vascular and lymphatic phenotypes that forms by a novel developmental process. PLoS Biol 12(7):e1001912. PubMed: 25051267 MGI: J:215599
Klein S; Seidler B; Kettenberger A; Sibaev A; Rohn M; Feil R; Allescher HD; Vanderwinden JM; Hofmann F; Schemann M; Rad R; Storr MA; Schmid RM; Schneider G; Saur D. 2013. Interstitial cells of Cajal integrate excitatory and inhibitory neurotransmission with intestinal slow-wave activity. Nat Commun 4:1630. PubMed: 23535651 MGI: J:204737
Klotz L; Norman S; Vieira JM; Masters M; Rohling M; Dube KN; Bollini S; Matsuzaki F; Carr CA; Riley PR. 2015. Cardiac lymphatics are heterogeneous in origin and respond to injury. Nature 522(7554):62-7. PubMed: 25992544 MGI: J:222246
Kobayashi H; Gilbert V; Liu Q; Kapitsinou PP; Unger TL; Rha J; Rivella S; Schlondorff D; Haase VH. 2012. Myeloid cell-derived hypoxia-inducible factor attenuates inflammation in unilateral ureteral obstruction-induced kidney injury. J Immunol 188(10):5106-15. PubMed: 22490864 MGI: J:188688
Kobayashi H; Liu Q; Binns TC; Urrutia AA; Davidoff O; Kapitsinou PP; Pfaff AS; Olauson H; Wernerson A; Fogo AB; Fong GH; Gross KW; Haase VH. 2016. Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin. J Clin Invest 126(5):1926-38. PubMed: 27088801 MGI: J:234932
Kobus K; Hartl D; Ott CE; Osswald M; Huebner A; von der Hagen M; Emmerich D; Kuhnisch J; Morreau H; Hes FJ; Mautner VF; Harder A; Tinschert S; Mundlos S; Kolanczyk M. 2015. Double NF1 inactivation affects adrenocortical function in NF1Prx1 mice and a human patient. PLoS One 10(3):e0119030. PubMed: 25775093 MGI: J:232916
Korotkevich E; Niwayama R; Courtois A; Friese S; Berger N; Buchholz F; Hiiragi T. 2017. The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo. Dev Cell 40(3):235-247.e7. PubMed: 28171747 MGI: J:239148
Korrapati S; Roux I; Glowatzki E; Doetzlhofer A. 2013. Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochlea. PLoS One 8(8):e73276. PubMed: 24023676 MGI: J:206406
Koso H; Tsuhako A; Lai CY; Baba Y; Otsu M; Ueno K; Nagasaki M; Suzuki Y; Watanabe S. 2016. Conditional rod photoreceptor ablation reveals Sall1 as a microglial marker and regulator of microglial morphology in the retina. Glia 64(11):2005-24. PubMed: 27459098 MGI: J:235625
Kozhemyakina E; Zhang M; Ionescu A; Ayturk UM; Ono N; Kobayashi A; Kronenberg H; Warman ML; Lassar AB. 2015. Identification of a Prg4-expressing articular cartilage progenitor cell population in mice. Arthritis Rheumatol 67(5):1261-73. PubMed: 25603997 MGI: J:232683
Kuchnio A; Moens S; Bruning U; Kuchnio K; Cruys B; Thienpont B; Broux M; Ungureanu AA; Leite de Oliveira R; Bruyere F; Cuervo H; Manderveld A; Carton A; Hernandez-Fernaud JR; Zanivan S; Bartic C; Foidart JM; Noel A; Vinckier S; Lambrechts D; Dewerchin M; Mazzone M; Carmeliet P. 2015. The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts. Cell Rep 12(6):992-1005. PubMed: 26235614 MGI: J:227777
Kurihara T; Westenskow PD; Krohne TU; Aguilar E; Johnson RS; Friedlander M. 2011. Astrocyte pVHL and HIF-alpha isoforms are required for embryonic-to-adult vascular transition in the eye. J Cell Biol 195(4):689-701. PubMed: 22084310 MGI: J:178823
Kwak H; Salvucci O; Weigert R; Martinez-Torrecuadrada JL; Henkemeyer M; Poulos MG; Butler JM; Tosato G. 2016. Sinusoidal ephrin receptor EPHB4 controls hematopoietic progenitor cell mobilization from bone marrow. J Clin Invest 126(12):4554-4568. PubMed: 27820703 MGI: J:239754
Kwon OJ; Zhang L; Ittmann MM; Xin L. 2014. Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin. Proc Natl Acad Sci U S A 111(5):E592-600. PubMed: 24367088 MGI: J:206383
Kwon OJ; Zhang L; Wang J; Su Q; Feng Q; Zhang XH; Mani SA; Paulter R; Creighton CJ; Ittmann MM; Xin L. 2016. Notch promotes tumor metastasis in a prostate-specific Pten-null mouse model. J Clin Invest 126(7):2626-41. PubMed: 27294523 MGI: J:237138
L'honore A; Commere PH; Ouimette JF; Montarras D; Drouin J; Buckingham M. 2014. Redox regulation by Pitx2 and Pitx3 is critical for fetal myogenesis. Dev Cell 29(4):392-405. PubMed: 24871946 MGI: J:213576
Lakhe-Reddy S; Li V; Arnold TD; Khan S; Schelling JR. 2014. Mesangial cell alphavbeta8-integrin regulates glomerular capillary integrity and repair. Am J Physiol Renal Physiol 306(12):F1400-9. PubMed: 24740792 MGI: J:211090
Lallemand Y; Moreau J; Cloment CS; Vives FL; Robert B. 2013. Generation and characterization of a tamoxifen inducible Msx1(CreERT2) knock-in allele. Genesis 51(2):110-9. PubMed: 23090744 MGI: J:194129
Lange SS; Bedford E; Reh S; Wittschieben JP; Carbajal S; Kusewitt DF; DiGiovanni J; Wood RD. 2013. Dual role for mammalian DNA polymerase zeta in maintaining genome stability and proliferative responses. Proc Natl Acad Sci U S A 110(8):E687-96. PubMed: 23386725 MGI: J:194536
Lange SS; Wittschieben JP; Wood RD. 2012. DNA polymerase zeta is required for proliferation of normal mammalian cells. Nucleic Acids Res 40(10):4473-82. PubMed: 22319213 MGI: J:197718
Laresgoiti U; Nikolic MZ; Rao C; Brady JL; Richardson RV; Batchen EJ; Chapman KE; Rawlins EL. 2016. Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development 143(20):3686-3699. PubMed: 27578791 MGI: J:237343
Laronda MM; Unno K; Ishi K; Serna VA; Butler LM; Mills AA; Orvis GD; Behringer RR; Deng C; Sinha S; Kurita T. 2013. Diethylstilbestrol induces vaginal adenosis by disrupting SMAD/RUNX1-mediated cell fate decision in the Mullerian duct epithelium. Dev Biol 381(1):5-16. PubMed: 23830984 MGI: J:200766
Le Bouffant R; Souquet B; Duval N; Duquenne C; Herve R; Frydman N; Robert B; Habert R; Livera G. 2011. Msx1 and Msx2 promote meiosis initiation. Development 138(24):5393-402. PubMed: 22071108 MGI: J:178676
Le Garrec JF; Ragni CV; Pop S; Dufour A; Olivo-Marin JC; Buckingham ME; Meilhac SM. 2013. Quantitative analysis of polarity in 3D reveals local cell coordination in the embryonic mouse heart. Development 140(2):395-404. PubMed: 23250213 MGI: J:191715
Le Roux I; Konge J; Le Cam L; Flamant P; Tajbakhsh S. 2015. Numb is required to prevent p53-dependent senescence following skeletal muscle injury. Nat Commun 6:8528. PubMed: 26503169 MGI: J:227915
Lee CL; Moding EJ; Cuneo KC; Li Y; Sullivan JM; Mao L; Washington I; Jeffords LB; Rodrigues RC; Ma Y; Das S; Kontos CD; Kim Y; Rockman HA; Kirsch DG. 2012. p53 functions in endothelial cells to prevent radiation-induced myocardial injury in mice. Sci Signal 5(234):ra52. PubMed: 22827996 MGI: J:231124
Lee JJ; Rothenberg ME; Seeley ES; Zimdahl B; Kawano S; Lu WJ; Shin K; Sakata-Kato T; Chen JK; Diehn M; Clarke MF; Beachy PA. 2016. Control of inflammation by stromal Hedgehog pathway activation restrains colitis. Proc Natl Acad Sci U S A 113(47):E7545-E7553. PubMed: 27815529 MGI: J:238842
Lee LK; Ghorbanian Y; Wang W; Wang Y; Kim YJ; Weissman IL; Inlay MA; Mikkola HK. 2016. LYVE1 Marks the Divergence of Yolk Sac Definitive Hemogenic Endothelium from the Primitive Erythroid Lineage. Cell Rep 17(9):2286-2298. PubMed: 27880904 MGI: J:241239
Lee SH; Johnson D; Luong R; Sun Z. 2015. Crosstalking between Androgen and PI3K/AKT Signaling Pathways in Prostate Cancer Cells. J Biol Chem 290(5):2759-68. PubMed: 25527506 MGI: J:217870
Lee SH; Johnson DT; Luong R; Yu EJ; Cunha GR; Nusse R; Sun Z. 2015. Wnt/beta-Catenin-Responsive Cells in Prostatic Development and Regeneration. Stem Cells 33(11):3356-67. PubMed: 26220362 MGI: J:228829
Lee YH; Petkova AP; Konkar AA; Granneman JG. 2015. Cellular origins of cold-induced brown adipocytes in adult mice. FASEB J 29(1):286-99. PubMed: 25392270 MGI: J:218206
Leshan RL; Greenwald-Yarnell M; Patterson CM; Gonzalez IE; Myers MG Jr. 2012. Leptin action through hypothalamic nitric oxide synthase-1-expressing neurons controls energy balance. Nat Med :. PubMed: 22522563 MGI: J:183754
Leung TH; Snyder ER; Liu Y; Wang J; Kim SK. 2015. A cellular, molecular, and pharmacological basis for appendage regeneration in mice. Genes Dev 29(20):2097-107. PubMed: 26494786 MGI: J:226615
Li C; Li M; Li S; Xing Y; Yang CY; Li A; Borok Z; De Langhe S; Minoo P. 2015. Progenitors of secondary crest myofibroblasts are developmentally committed in early lung mesoderm. Stem Cells 33(3):999-1012. PubMed: 25448080 MGI: J:223861
Li J; Chatzeli L; Panousopoulou E; Tucker AS; Green JB. 2016. Epithelial stratification and placode invagination are separable functions in early morphogenesis of the molar tooth. Development 143(4):670-81. PubMed: 26755699 MGI: J:239975
Li J; Liu CH; Sun Y; Gong Y; Fu Z; Evans LP; Tian KT; Juan AM; Hurst CG; Mammoto A; Chen J. 2014. Endothelial TWIST1 promotes pathological ocular angiogenesis. Invest Ophthalmol Vis Sci 55(12):8267-77. PubMed: 25414194 MGI: J:230294
Li J; Miao L; Zhao C; Shaikh Qureshi WM; Shieh D; Guo H; Lu Y; Hu S; Huang A; Zhang L; Cai CL; Wan LQ; Xin H; Vincent P; Singer HA; Zheng Y; Cleaver O; Fan ZC; Wu M. 2017. CDC42 is required for epicardial and pro-epicardial development by mediating FGF receptor trafficking to the plasma membrane. Development 144(9):1635-1647. PubMed: 28465335 MGI: J:241636
Li J; Sun H; Feltri ML; Mercurio AM. 2015. Integrin beta4 regulation of PTHrP underlies its contribution to mammary gland development. Dev Biol 407(2):313-20. PubMed: 26432258 MGI: J:227059
Li W; Li Q; Jiao Y; Qin L; Ali R; Zhou J; Ferruzzi J; Kim RW; Geirsson A; Dietz HC; Offermanns S; Humphrey JD; Tellides G. 2014. Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis. J Clin Invest 124(2):755-67. PubMed: 24401272 MGI: J:207994
Li Y; Dunphy JM; Pedraza CE; Lynch CR; Cardona SM; Macklin WB; Lynch WP. 2016. Ecotropic Murine Leukemia Virus Infection of Glial Progenitors Interferes with Oligodendrocyte Differentiation: Implications for Neurovirulence. J Virol 90(7):3385-99. PubMed: 26764005 MGI: J:230503
Li Y; Wang J; Asahina K. 2013. Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver injury. Proc Natl Acad Sci U S A 110(6):2324-9. PubMed: 23345421 MGI: J:194339
Liang D; Wang X; Mittal A; Dhiman S; Hou SY; Degenhardt K; Astrof S. 2014. Mesodermal expression of integrin alpha5beta1 regulates neural crest development and cardiovascular morphogenesis. Dev Biol 395(2):232-44. PubMed: 25242040 MGI: J:216613
Lilla JN; Chen CC; Mukai K; Benbarak MJ; Franco CB; Kalesnikoff J; Yu M; Tsai M; Piliponsky AM; Galli SJ. 2011. Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice. Blood 118(26):6930-8. PubMed: 22001390 MGI: J:179080
Lim A; Shin K; Zhao C; Kawano S; Beachy PA. 2014. Spatially restricted Hedgehog signalling regulates HGF-induced branching of the adult prostate. Nat Cell Biol 16(12):1135-45. PubMed: 25362352 MGI: J:217750
Lim H; Sharoukhov D; Kassim I; Zhang Y; Salzer JL; Melendez-Vasquez CV. 2014. Label-free imaging of Schwann cell myelination by third harmonic generation microscopy. Proc Natl Acad Sci U S A 111(50):18025-30. PubMed: 25453108 MGI: J:217815
Lim J; Tu X; Choi K; Akiyama H; Mishina Y; Long F. 2015. BMP-Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse. Dev Biol 400(1):132-8. PubMed: 25641697 MGI: J:221163
Lim X; Tan SH; Koh WL; Chau RM; Yan KS; Kuo CJ; van Amerongen R; Klein AM; Nusse R. 2013. Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling. Science 342(6163):1226-30. PubMed: 24311688 MGI: J:205263
Lin C; Song H; Huang C; Yao E; Gacayan R; Xu SM; Chuang PT. 2012. Alveolar type II cells possess the capability of initiating lung tumor development. PLoS One 7(12):e53817. PubMed: 23285300 MGI: J:195738
Lin C; Yin Y; Stemler K; Humphrey P; Kibel AS; Mysorekar IU; Ma L. 2013. Constitutive beta-catenin activation induces male-specific tumorigenesis in the bladder urothelium. Cancer Res 73(19):5914-25. PubMed: 23928991 MGI: J:202618
Lin Q; Wesson RN; Maeda H; Wang Y; Cui Z; Liu JO; Cameron AM; Gao B; Montgomery RA; Williams GM; Sun Z. 2014. Pharmacological Mobilization of Endogenous Stem Cells Significantly Promotes Skin Regeneration after Full-Thickness Excision: The Synergistic Activity of AMD3100 and Tacrolimus. J Invest Dermatol 134(9):2458-68. PubMed: 24682043 MGI: J:212838
Lin RS; Jimenez-Movilla M; Dean J. 2014. Figla-Cre transgenic mice expressing myristoylated EGFP in germ cells provide a model for investigating perinatal oocyte dynamics. PLoS One 9(1):e84477. PubMed: 24400092 MGI: J:209947
Lindskog H; Kim YH; Jelin EB; Kong Y; Guevara-Gallardo S; Kim TN; Wang RA. 2014. Molecular identification of venous progenitors in the dorsal aorta reveals an aortic origin for the cardinal vein in mammals. Development 141(5):1120-8. PubMed: 24550118 MGI: J:208418
Liu CY; Dube PE; Girish N; Reddy AT; Polk DB. 2015. Optical reconstruction of murine colorectal mucosa at cellular resolution. Am J Physiol Gastrointest Liver Physiol 308(9):G721-35. PubMed: 25721303 MGI: J:224167
Liu G; Sgobio C; Gu X; Sun L; Lin X; Yu J; Parisiadou L; Xie C; Sastry N; Ding J; Lohr KM; Miller GW; Mateo Y; Lovinger DM; Cai H. 2015. Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression. Hum Mol Genet :. PubMed: 26123485 MGI: J:222392
Liu J; Willet SG; Bankaitis ED; Xu Y; Wright CV; Gu G. 2013. Non-parallel recombination limits Cre-LoxP-based reporters as precise indicators of conditional genetic manipulation. Genesis 51(6):436-42. PubMed: 23441020 MGI: J:204870
Liu L; Li M; Spangler LC; Spear C; Veenstra M; Darnall L; Chang C; Cotleur AC; Ransohoff RM. 2013. Functional defect of peripheral neutrophils in mice with induced deletion of CXCR2. Genesis 51(8):587-95. PubMed: 23650205 MGI: J:204482
Liu P; Ping Y; Ma M; Zhang D; Liu C; Zaidi S; Gao S; Ji Y; Lou F; Yu F; Lu P; Stachnik A; Bai M; Wei C; Zhang L; Wang K; Chen R; New MI; Rowe DW; Yuen T; Sun L; Zaidi M. 2016. Anabolic actions of Notch on mature bone. Proc Natl Acad Sci U S A 113(15):E2152-61. PubMed: 27036007 MGI: J:232117
Liu S; Herault Y; Pavlovic G; Leask A. 2014. Skin progenitor cells contribute to bleomycin-induced skin fibrosis. Arthritis Rheumatol 66(3):707-13. PubMed: 24574231 MGI: J:234752
Liu S; Young SM; Varisco BM. 2014. Dynamic expression of chymotrypsin-like elastase 1 over the course of murine lung development. Am J Physiol Lung Cell Mol Physiol 306(12):L1104-16. PubMed: 24793170 MGI: J:221734
Liu W; Bi P; Shan T; Yang X; Yin H; Wang YX; Liu N; Rudnicki MA; Kuang S. 2013. miR-133a Regulates Adipocyte Browning In Vivo. PLoS Genet 9(7):e1003626. PubMed: 23874225 MGI: J:199296
Liu W; Wei-LaPierre L; Klose A; Dirksen RT; Chakkalakal JV. 2015. Inducible depletion of adult skeletal muscle stem cells impairs the regeneration of neuromuscular junctions. Elife 4:. PubMed: 26312504 MGI: J:226797
Liu Y; Liu X; Hao W; Decker Y; Schomburg R; Fulop L; Pasparakis M; Menger MD; Fassbender K. 2014. IKKbeta deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology. J Neurosci 34(39):12982-99. PubMed: 25253847 MGI: J:216611
Lo HG; Jin RU; Sibbel G; Liu D; Karki A; Joens MS; Madison BB; Zhang B; Blanc V; Fitzpatrick JA; Davidson NO; Konieczny SF; Mills JC. 2017. A single transcription factor is sufficient to induce and maintain secretory cell architecture. Genes Dev 31(2):154-171. PubMed: 28174210 MGI: J:239586
Lockhart MM; Boukens BJ; Phelps AL; Brown CL; Toomer KA; Burns TA; Mukherjee RD; Norris RA; Trusk TC; van den Hoff MJ; Wessels A. 2014. Alk3 mediated Bmp signaling controls the contribution of epicardially derived cells to the tissues of the atrioventricular junction. Dev Biol 396(1):8-18. PubMed: 25300579 MGI: J:217173
Long JZ; Svensson KJ; Tsai L; Zeng X; Roh HC; Kong X; Rao RR; Lou J; Lokurkar I; Baur W; Castellot JJ Jr; Rosen ED; Spiegelman BM. 2014. A smooth muscle-like origin for beige adipocytes. Cell Metab 19(5):810-20. PubMed: 24709624 MGI: J:214781
Lopes M; Gooupille O; Saint Cloment C; Robert B. 2012. Msx1 is expressed in retina endothelial cells at artery branching sites Biol Open 1(4):376-384. PubMed: 23213427 MGI: J:184582
Lopes M; Goupille O; Cloment CS; Lallemand Y; Cumano A; Robert B. 2011. Msx genes define a population of mural cell precursors required for head blood vessel maturation. Development 138(14):3055-66. PubMed: 21693521 MGI: J:173525
Lowery JW; Intini G; Gamer L; Lotinun S; Salazar VS; Ote S; Cox K; Baron R; Rosen V. 2015. Loss of BMPR2 leads to high bone mass due to increased osteoblast activity. J Cell Sci 128(7):1308-15. PubMed: 25663702 MGI: J:231506
Lu H; Lu Q; Gaddipati S; Kasetti RB; Wang W; Pasparakis M; Kaplan HJ; Li Q. 2014. IKK2 inhibition attenuates laser-induced choroidal neovascularization. PLoS One 9(1):e87530. PubMed: 24489934 MGI: J:212688
Lu TL; Chen CM. 2015. Differential requirements for beta-catenin in murine prostate cancer originating from basal versus luminal cells. J Pathol 236(3):290-301. PubMed: 25712462 MGI: J:222750
Lu TL; Huang YF; You LR; Chao NC; Su FY; Chang JL; Chen CM. 2013. Conditionally ablated Pten in prostate basal cells promotes basal-to-luminal differentiation and causes invasive prostate cancer in mice. Am J Pathol 182(3):975-91. PubMed: 23313138 MGI: J:223065
Lua I; Li Y; Pappoe LS; Asahina K. 2015. Myofibroblastic Conversion and Regeneration of Mesothelial Cells in Peritoneal and Liver Fibrosis. Am J Pathol 185(12):3258-73. PubMed: 26598235 MGI: J:228136
Lucitti JL; Mackey JK; Morrison JC; Haigh JJ; Adams RH; Faber JE. 2012. Formation of the collateral circulation is regulated by vascular endothelial growth factor-A and a disintegrin and metalloprotease family members 10 and 17. Circ Res 111(12):1539-50. PubMed: 22965144 MGI: J:212884
Luo J; Elwood F; Britschgi M; Villeda S; Zhang H; Ding Z; Zhu L; Alabsi H; Getachew R; Narasimhan R; Wabl R; Fainberg N; James ML; Wong G; Relton J; Gambhir SS; Pollard JW; Wyss-Coray T. 2013. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival. J Exp Med 210(1):157-72. PubMed: 23296467 MGI: J:194761
Luo L; Uehara H; Zhang X; Das SK; Olsen T; Holt D; Simonis JM; Jackman K; Singh N; Miya TR; Huang W; Ahmed F; Bastos-Carvalho A; Le YZ; Mamalis C; Chiodo VA; Hauswirth WW; Baffi J; Lacal PM; Orecchia A; Ferrara N; Gao G; Young-Hee K; Fu Y; Owen L; Albuquerque R; Baehr W; Thomas K; Li DY; Chalam KV; Shibuya M; Grisanti S; Wilson DJ; Ambati J; Ambati BK. 2013. Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. Elife 2:e00324. PubMed: 23795287 MGI: J:199828
Lynch TJ; Anderson PJ; Xie W; Crooke AK; Liu X; Tyler SR; Luo M; Kusner DM; Zhang Y; Neff T; Burnette DC; Walters KS; Goodheart MJ; Parekh KR; Engelhardt JF. 2016. Wnt Signaling Regulates Airway Epithelial Stem Cells in Adult Murine Submucosal Glands. Stem Cells :. PubMed: 27341073 MGI: J:238359
Lyndaker AM; Lim PX; Mleczko JM; Diggins CE; Holloway JK; Holmes RJ; Kan R; Schlafer DH; Freire R; Cohen PE; Weiss RS. 2013. Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance. PLoS Genet 9(2):e1003320. PubMed: 23468651 MGI: J:195191
Lyons DB; Allen WE; Goh T; Tsai L; Barnea G; Lomvardas S. 2013. An epigenetic trap stabilizes singular olfactory receptor expression. Cell 154(2):325-36. PubMed: 23870122 MGI: J:200085
Ma A; Wang L; Gao Y; Chang Z; Peng H; Zeng N; Gui YS; Tian X; Li X; Cai B; Zhang H; Xu KF. 2014. Tsc1 deficiency-mediated mTOR hyperactivation in vascular endothelial cells causes angiogenesis defects and embryonic lethality. Hum Mol Genet 23(3):693-705. PubMed: 24129405 MGI: J:208733
Ma CY; Shi GY; Shi CS; Kao YC; Lin SW; Wu HL. 2012. Monocytic thrombomodulin triggers LPS- and gram-negative bacteria-induced inflammatory response. J Immunol 188(12):6328-37. PubMed: 22573811 MGI: J:188879
Ma M; Tian X; Igarashi P; Pazour GJ; Somlo S. 2013. Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease. Nat Genet 45(9):1004-12. PubMed: 23892607 MGI: J:205308
Ma S; Kwon HJ; Huang Z. 2012. Ric-8a, a guanine nucleotide exchange factor for heterotrimeric G proteins, regulates bergmann glia-basement membrane adhesion during cerebellar foliation. J Neurosci 32(43):14979-93. PubMed: 23100420 MGI: J:191222
Mancarella S; Potireddy S; Wang Y; Gao H; Gandhirajan RK; Autieri M; Scalia R; Cheng Z; Wang H; Madesh M; Houser SR; Gill DL. 2013. Targeted STIM deletion impairs calcium homeostasis, NFAT activation, and growth of smooth muscle. FASEB J 27(3):893-906. PubMed: 23159931 MGI: J:196988
Mangiavini L; Merceron C; Araldi E; Khatri R; Gerard-O'Riley R; Wilson TL; Rankin EB; Giaccia AJ; Schipani E. 2014. Loss of VHL in mesenchymal progenitors of the limb bud alters multiple steps of endochondral bone development. Dev Biol 393(1):124-36. PubMed: 24972088 MGI: J:214967
Mangiavini L; Merceron C; Araldi E; Khatri R; Gerard-O'Riley R; Wilson TL; Sandusky G; Abadie J; Lyons KM; Giaccia AJ; Schipani E. 2015. Fibrosis and Hypoxia-Inducible Factor-1alpha-Dependent Tumors of the Soft Tissue on Loss of Von Hippel-Lindau in Mesenchymal Progenitors. Am J Pathol 185(11):3090-101. PubMed: 26348575 MGI: J:226906
Mao Y; Kuta A; Crespo-Enriquez I; Whiting D; Martin T; Mulvaney J; Irvine KD; Francis-West P. 2016. Dchs1-Fat4 regulation of polarized cell behaviours during skeletal morphogenesis. Nat Commun 7:11469. PubMed: 27145737 MGI: J:239940
Marchesi C; Rehman A; Rautureau Y; Kasal DA; Briet M; Leibowitz A; Simeone SM; Ebrahimian T; Neves MF; Offermanns S; Gonzalez FJ; Paradis P; Schiffrin EL. 2013. Protective role of vascular smooth muscle cell PPARgamma in angiotensin II-induced vascular disease. Cardiovasc Res 97(3):562-70. PubMed: 23250918 MGI: J:210280
Marriott S; Baskir RS; Gaskill C; Menon S; Carrier EJ; Williams J; Talati M; Helm K; Alford CE; Kropski JA; Loyd J; Wheeler L; Johnson J; Austin E; Nozik-Grayck E; Meyrick B; West JD; Klemm DJ; Majka SM. 2014. ABCG2pos lung mesenchymal stem cells are a novel pericyte subpopulation that contributes to fibrotic remodeling. Am J Physiol Cell Physiol 307(8):C684-98. PubMed: 25122876 MGI: J:223114
Martin EI; Ressler KJ; Jasnow AM; Dabrowska J; Hazra R; Rainnie DG; Nemeroff CB; Owens MJ. 2010. A novel transgenic mouse for gene-targeting within cells that express corticotropin-releasing factor. Biol Psychiatry 67(12):1212-6. PubMed: 20303068 MGI: J:162037
Massarwa R; Niswander L. 2013. In toto live imaging of mouse morphogenesis and new insights into neural tube closure. Development 140(1):226-36. PubMed: 23175632 MGI: J:191070
Mathew SJ; Hansen JM; Merrell AJ; Murphy MM; Lawson JA; Hutcheson DA; Hansen MS; Angus-Hill M; Kardon G. 2011. Connective tissue fibroblasts and Tcf4 regulate myogenesis. Development 138(2):371-84. PubMed: 21177349 MGI: J:167712
Mayeuf-Louchart A; Montarras D; Bodin C; Kume T; Vincent SD; Buckingham M. 2016. Endothelial cell specification in the somite is compromised in Pax3-positive progenitors of Foxc1/2 conditional mutants, with loss of forelimb myogenesis. Development 143(5):872-9. PubMed: 26839363 MGI: J:240081
McAllister F; Bailey JM; Alsina J; Nirschl CJ; Sharma R; Fan H; Rattigan Y; Roeser JC; Lankapalli RH; Zhang H; Jaffee EM; Drake CG; Housseau F; Maitra A; Kolls JK; Sears CL; Pardoll DM; Leach SD. 2014. Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia. Cancer Cell 25(5):621-37. PubMed: 24823639 MGI: J:210592
McBride SH; McKenzie JA; Bedrick BS; Kuhlmann P; Pasteris JD; Rosen V; Silva MJ. 2014. Long bone structure and strength depend on BMP2 from osteoblasts and osteocytes, but not vascular endothelial cells. PLoS One 9(5):e96862. PubMed: 24837969 MGI: J:216332
Mederacke I; Hsu CC; Troeger JS; Huebener P; Mu X; Dapito DH; Pradere JP; Schwabe RF. 2013. Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology. Nat Commun 4:2823. PubMed: 24264436 MGI: J:205330
Meng X; Vander Ark A; Lee P; Hostetter G; Bhowmick NA; Matrisian LM; Williams BO; Miranti CK; Li X. 2016. Myeloid-specific TGF-beta signaling in bone promotes basic-FGF and breast cancer bone metastasis. Oncogene 35(18):2370-8. PubMed: 26279296 MGI: J:234208
Merceron C; Mangiavini L; Robling A; Wilson TL; Giaccia AJ; Shapiro IM; Schipani E; Risbud MV. 2014. Loss of HIF-1alpha in the notochord results in cell death and complete disappearance of the nucleus pulposus. PLoS One 9(10):e110768. PubMed: 25338007 MGI: J:223545
Mereness AL; Murphy ZC; Forrestel AC; Butler S; Ko C; Richards JS; Sellix MT. 2016. Conditional Deletion of Bmal1 in Ovarian Theca Cells Disrupts Ovulation in Female Mice. Endocrinology 157(2):913-27. PubMed: 26671182 MGI: J:233850
Merrell AJ; Ellis BJ; Fox ZD; Lawson JA; Weiss JA; Kardon G. 2015. Muscle connective tissue controls development of the diaphragm and is a source of congenital diaphragmatic hernias. Nat Genet 47(5):496-504. PubMed: 25807280 MGI: J:231793
Mescher M; Jeong P; Knapp SK; Rubsam M; Saynisch M; Kranen M; Landsberg J; Schlaak M; Mauch C; Tuting T; Niessen CM; Iden S. 2017. The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant melanoma. J Exp Med 214(2):339-358. PubMed: 28096290 MGI: J:240961
Michalski JP; Anderson C; Beauvais A; De Repentigny Y; Kothary R. 2011. The Proteolipid Protein Promoter Drives Expression outside of the Oligodendrocyte Lineage during Embryonic and Early Postnatal Development. PLoS One 6(5):e19772. PubMed: 21572962 MGI: J:172435
Michalski JP; Cummings SE; O'Meara RW; Kothary R. 2016. Integrin-linked kinase regulates oligodendrocyte cytoskeleton, growth cone, and adhesion dynamics. J Neurochem 136(3):536-49. PubMed: 26614167 MGI: J:229386
Mikedis MM; Downs KM. 2017. PRDM1/BLIMP1 is widely distributed to the nascent fetal-placental interface in the mouse gastrula. Dev Dyn 246(1):50-71. PubMed: 27696611 MGI: J:237427
Millington G; Elliott KH; Chang YT; Chang CF; Dlugosz A; Brugmann SA. 2017. Cilia-dependent GLI processing in neural crest cells is required for tongue development. Dev Biol 424(2):124-137. PubMed: 28286175 MGI: J:241005
Mirantes C; Dosil MA; Hills D; Yang J; Eritja N; Santacana M; Gatius S; Vilardell F; Medvinsky A; Matias-Guiu X; Dolcet X. 2016. Deletion of Pten in CD45-expressing cells leads to development of T-cell lymphoblastic lymphoma but not myeloid malignancies. Blood 127(15):1907-11. PubMed: 26773036 MGI: J:232644
Mirantes C; Eritja N; Dosil MA; Santacana M; Pallares J; Gatius S; Bergada L; Maiques O; Matias-Guiu X; Dolcet X. 2013. An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias. Dis Model Mech 6(3):710-20. PubMed: 23471917 MGI: J:196368
Misra A; Sheikh AQ; Kumar A; Luo J; Zhang J; Hinton RB; Smoot L; Kaplan P; Urban Z; Qyang Y; Tellides G; Greif DM. 2016. Integrin beta3 inhibition is a therapeutic strategy for supravalvular aortic stenosis. J Exp Med 213(3):451-63. PubMed: 26858344 MGI: J:232801
Mitchell EH; Serra R. 2014. Normal mammary development and function in mice with Ift88 deleted in MMTV- and K14-Cre expressing cells. Cilia 3(1):4. PubMed: 24594320 MGI: J:210639
Mittal P; Shin YH; Yatsenko SA; Castro CA; Surti U; Rajkovic A. 2015. Med12 gain-of-function mutation causes leiomyomas and genomic instability. J Clin Invest 125(8):3280-4. PubMed: 26193636 MGI: J:222990
Mleynek TM; Chan AC; Redd M; Gibson CC; Davis CT; Shi DS; Chen T; Carter KL; Ling J; Blanco R; Gerhardt H; Whitehead K; Li DY. 2014. Lack of CCM1 induces hypersprouting and impairs response to flow. Hum Mol Genet 23(23):6223-34. PubMed: 24990152 MGI: J:215458
Moding EJ; Lee CL; Castle KD; Oh P; Mao L; Zha S; Min HD; Ma Y; Das S; Kirsch DG. 2014. Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endothelium. J Clin Invest 124(8):3325-38. PubMed: 25036710 MGI: J:215614
Mondal S; Pahan K. 2015. Cinnamon ameliorates experimental allergic encephalomyelitis in mice via regulatory T cells: implications for multiple sclerosis therapy. PLoS One 10(1):e0116566. PubMed: 25569428 MGI: J:225658
Monkkonen T; Landua JD; Visbal AP; Lewis MT. 2017. Epithelial and non-epithelial Ptch1 play opposing roles to regulate proliferation and morphogenesis of the mouse mammary gland. Development 144(7):1317-1327. PubMed: 28275010 MGI: J:240027
Moriyama M; Fukuhara T; Britschgi M; He Y; Narasimhan R; Villeda S; Molina H; Huber BT; Holers M; Wyss-Coray T. 2011. Complement Receptor 2 Is Expressed in Neural Progenitor Cells and Regulates Adult Hippocampal Neurogenesis. J Neurosci 31(11):3981-3989. PubMed: 21411641 MGI: J:170456
Motley MP; Madsen DH; Jurgensen HJ; Spencer DE; Szabo R; Holmbeck K; Flick MJ; Lawrence DA; Castellino FJ; Weigert R; Bugge TH. 2016. A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo. Blood 127(9):1085-96. PubMed: 26647393 MGI: J:232502
Mourikis P; Gopalakrishnan S; Sambasivan R; Tajbakhsh S. 2012. Cell-autonomous Notch activity maintains the temporal specification potential of skeletal muscle stem cells. Development 139(24):4536-48. PubMed: 23136394 MGI: J:189959
Mourikis P; Sambasivan R; Castel D; Rocheteau P; Bizzarro V; Tajbakhsh S. 2012. A critical requirement for notch signaling in maintenance of the quiescent skeletal muscle stem cell state. Stem Cells 30(2):243-52. PubMed: 22069237 MGI: J:190192
Moynihan KD; Opel CF; Szeto GL; Tzeng A; Zhu EF; Engreitz JM; Williams RT; Rakhra K; Zhang MH; Rothschilds AM; Kumari S; Kelly RL; Kwan BH; Abraham W; Hu K; Mehta NK; Kauke MJ; Suh H; Cochran JR; Lauffenburger DA; Wittrup KD; Irvine DJ. 2016. Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses. Nat Med 22(12):1402-1410. PubMed: 27775706 MGI: J:240803
Murphy MM; Lawson JA; Mathew SJ; Hutcheson DA; Kardon G. 2011. Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration. Development 138(17):3625-37. PubMed: 21828091 MGI: J:174914
Murphy PA; Begum S; Hynes RO. 2015. Tumor angiogenesis in the absence of fibronectin or its cognate integrin receptors. PLoS One 10(3):e0120872. PubMed: 25807551 MGI: J:229618
Murphy PA; Hynes RO. 2014. Alternative splicing of endothelial fibronectin is induced by disturbed hemodynamics and protects against hemorrhage of the vessel wall. Arterioscler Thromb Vasc Biol 34(9):2042-50. PubMed: 24903094 MGI: J:227103
Murphy PA; Kim TN; Huang L; Nielsen CM; Lawton MT; Adams RH; Schaffer CB; Wang RA. 2014. Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels. Proc Natl Acad Sci U S A 111(50):18007-12. PubMed: 25468970 MGI: J:217811
Murphy PA; Kim TN; Lu G; Bollen AW; Schaffer CB; Wang RA. 2012. Notch4 normalization reduces blood vessel size in arteriovenous malformations. Sci Transl Med 4(117):117ra8. PubMed: 22261032 MGI: J:183703
Nadeau V; Charron J. 2014. Essential role of the ERK/MAPK pathway in blood-placental barrier formation. Development 141(14):2825-37. PubMed: 24948605 MGI: J:213868
Nagalakshmi VK; Lindner V; Wessels A; Yu J. 2015. microRNA-dependent temporal gene expression in the ureteric bud epithelium during mammalian kidney development. Dev Dyn 244(3):444-56. PubMed: 25369991 MGI: J:219223
Nandadasa S; Nelson CM; Apte SS. 2015. ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation. Cell Rep 11(10):1519-28. PubMed: 26027930 MGI: J:228583
Neal MD; Sodhi CP; Jia H; Dyer M; Egan CE; Yazji I; Good M; Afrazi A; Marino R; Slagle D; Ma C; Branca MF; Prindle T Jr; Grant Z; Ozolek J; Hackam DJ. 2012. Toll-like receptor 4 is expressed on intestinal stem cells and regulates their proliferation and apoptosis via the p53 up-regulated modulator of apoptosis. J Biol Chem 287(44):37296-308. PubMed: 22955282 MGI: J:192131
Nedvetsky PI; Emmerson E; Finley JK; Ettinger A; Cruz-Pacheco N; Prochazka J; Haddox CL; Northrup E; Hodges C; Mostov KE; Hoffman MP; Knox SM. 2014. Parasympathetic innervation regulates tubulogenesis in the developing salivary gland. Dev Cell 30(4):449-62. PubMed: 25158854 MGI: J:232152
Nedvetsky PI; Zhao X; Mathivet T; Aspalter IM; Stanchi F; Metzger RJ; Mostov KE; Gerhardt H. 2016. cAMP-dependent protein kinase A (PKA) regulates angiogenesis by modulating tip cell behavior in a Notch-independent manner. Development 143(19):3582-3590. PubMed: 27702786 MGI: J:236379
Nik AM; Johansson JA; Ghiami M; Reyahi A; Carlsson P. 2016. Foxf2 is required for secondary palate development and Tgfbeta signaling in palatal shelf mesenchyme. Dev Biol 415(1):14-23. PubMed: 27180663 MGI: J:234115
Norden J; Greulich F; Rudat C; Taketo MM; Kispert A. 2011. Wnt/beta-catenin signaling maintains the mesenchymal precursor pool for murine sinus horn formation. Circ Res 109(6):e42-50. PubMed: 21757651 MGI: J:188836
Ntokou A; Klein F; Dontireddy D; Becker S; Bellusci S; Richardson WD; Szibor M; Braun T; Morty RE; Seeger W; Voswinckel R; Ahlbrecht K. 2015. Characterization of the platelet-derived growth factor receptor-alpha-positive cell lineage during murine late lung development. Am J Physiol Lung Cell Mol Physiol 309(9):L942-58. PubMed: 26320158 MGI: J:232876
Odelin G; Faure E; Kober F; Maurel-Zaffran C; Theron A; Coulpier F; Guillet B; Bernard M; Avierinos JF; Charnay P; Topilko P; Zaffran S. 2014. Loss of Krox20 results in aortic valve regurgitation and impaired transcriptional activation of fibrillar collagen genes. Cardiovasc Res 104(3):443-55. PubMed: 25344368 MGI: J:230306
Oladipupo SS; Smith C; Santeford A; Park C; Sene A; Wiley LA; Osei-Owusu P; Hsu J; Zapata N; Liu F; Nakamura R; Lavine KJ; Blumer KJ; Choi K; Apte RS; Ornitz DM. 2014. Endothelial cell FGF signaling is required for injury response but not for vascular homeostasis. Proc Natl Acad Sci U S A 111(37):13379-84. PubMed: 25139991 MGI: J:216405
Otero DC; Baker DP; David M. 2013. IRF7-Dependent IFN-beta Production in Response to RANKL Promotes Medullary Thymic Epithelial Cell Development. J Immunol 190(7):3289-98. PubMed: 23440417 MGI: J:194737
Outeda P; Huso DL; Fisher SA; Halushka MK; Kim H; Qian F; Germino GG; Watnick T. 2014. Polycystin signaling is required for directed endothelial cell migration and lymphatic development. Cell Rep 7(3):634-44. PubMed: 24767998 MGI: J:211806
Pan JH; Adair-Kirk TL; Patel AC; Huang T; Yozamp NS; Xu J; Reddy EP; Byers DE; Pierce RA; Holtzman MJ; Brody SL. 2014. Myb permits multilineage airway epithelial cell differentiation. Stem Cells 32(12):3245-56. PubMed: 25103188 MGI: J:218553
Papangeli I; Kim J; Maier I; Park S; Lee A; Kang Y; Tanaka K; Khan OF; Ju H; Kojima Y; Red-Horse K; Anderson DG; Siekmann AF; Chun HJ. 2016. MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation. Nat Commun 7:11268. PubMed: 27068353 MGI: J:236895
Papangeli I; Sharma B; Chun HJ. 2015. Letter by Papangeli et al Regarding Article, "The ERG-APLNR Axis Controls Pulmonary Venule Endothelial Proliferation in Pulmonary Veno-Occlusive Disease". Circulation 132(2):e16. PubMed: 26169651 MGI: J:239055
Papoutsi T; Odelin G; Moore-Morris T; Puceat M; de la Pompa JL; Robert B; Zaffran S. 2015. Msx1(cre) (ERT) (2) knock-In allele: A useful tool to target embryonic and adult cardiac valves. Genesis 53(5):337-45. PubMed: 25950518 MGI: J:221643
Park D; Spencer JA; Koh BI; Kobayashi T; Fujisaki J; Clemens TL; Lin CP; Kronenberg HM; Scadden DT. 2012. Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration. Cell Stem Cell 10(3):259-72. PubMed: 22385654 MGI: J:185671
Park SW; Kim M; Kim JY; Brown KM; Haase VH; D'Agati VD; Lee HT. 2012. Proximal tubule sphingosine kinase-1 has a critical role in A1 adenosine receptor-mediated renal protection from ischemia. Kidney Int 82(8):878-91. PubMed: 22695326 MGI: J:198171
Pei L; Mu Y; Leblanc M; Alaynick W; Barish GD; Pankratz M; Tseng TW; Kaufman S; Liddle C; Yu RT; Downes M; Pfaff SL; Auwerx J; Gage FH; Evans RM. 2015. Dependence of hippocampal function on ERRgamma-regulated mitochondrial metabolism. Cell Metab 21(4):628-36. PubMed: 25863252 MGI: J:221572
Pelle DW; Peacock JD; Schmidt CL; Kampfschulte K; Scholten DJ 2nd; Russo SS; Easton KJ; Steensma MR. 2014. Genetic and functional studies of the intervertebral disc: a novel murine intervertebral disc model. PLoS One 9(12):e112454. PubMed: 25474689 MGI: J:225682
Peng T; Tian Y; Boogerd CJ; Lu MM; Kadzik RS; Stewart KM; Evans SM; Morrisey EE. 2013. Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor. Nature 500(7464):589-92. PubMed: 23873040 MGI: J:204743
Perez-Millan MI; Zeidler MG; Saunders TL; Camper SA; Davis SW. 2013. Efficient, specific, developmentally appropriate cre-mediated recombination in anterior pituitary gonadotropes and thyrotropes. Genesis 51(11):785-92. PubMed: 23996951 MGI: J:204533
Pertuy F; Aguilar A; Strassel C; Eckly A; Freund JN; Duluc I; Gachet C; Lanza F; Leon C. 2015. Broader expression of the mouse platelet factor 4-cre transgene beyond the megakaryocyte lineage. J Thromb Haemost 13(1):115-25. PubMed: 25393502 MGI: J:232618
Pignon JC; Grisanzio C; Geng Y; Song J; Shivdasani RA; Signoretti S. 2013. p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia. Proc Natl Acad Sci U S A 110(20):8105-10. PubMed: 23620512 MGI: J:197339
Pimeisl IM; Tanriver Y; Daza RA; Vauti F; Hevner RF; Arnold HH; Arnold SJ. 2013. Generation and characterization of a tamoxifen-inducible Eomes mouse line. Genesis :. PubMed: 23897762 MGI: J:198846
Pitzonka L; Wang X; Ullas S; Wolff DW; Wang Y; Goodrich DW. 2013. The THO ribonucleoprotein complex is required for stem cell homeostasis in the adult mouse small intestine. Mol Cell Biol 33(17):3505-14. PubMed: 23816884 MGI: J:204752
Pohlkamp T; Steller L; May P; Gunther T; Schule R; Frotscher M; Herz J; Bock HH. 2014. Generation and Characterization of an Nse-CreERT2 Transgenic Line Suitable for Inducible Gene Manipulation in Cerebellar Granule Cells. PLoS One 9(6):e100384. PubMed: 24950299 MGI: J:210655
Pond AC; Bin X; Batts T; Roarty K; Hilsenbeck S; Rosen JM. 2013. Fibroblast growth factor receptor signaling is essential for normal mammary gland development and stem cell function. Stem Cells 31(1):178-89. PubMed: 23097355 MGI: J:194704
Poulson ND; Lechler T. 2010. Robust control of mitotic spindle orientation in the developing epidermis. J Cell Biol 191(5):915-22. PubMed: 21098114 MGI: J:166997
Powers BE; Sellers DL; Lovelett EA; Cheung W; Aalami SP; Zapertov N; Maris DO; Horner PJ. 2013. Remyelination reporter reveals prolonged refinement of spontaneously regenerated myelin. Proc Natl Acad Sci U S A 110(10):4075-80. PubMed: 23431182 MGI: J:196074
Prendiville TW; Guo H; Lin Z; Zhou P; Stevens SM; He A; VanDusen N; Chen J; Zhong L; Wang DZ; Gao G; Pu WT. 2015. Novel Roles of GATA4/6 in the Postnatal Heart Identified through Temporally Controlled, Cardiomyocyte-Specific Gene Inactivation by Adeno-Associated Virus Delivery of Cre Recombinase. PLoS One 10(5):e0128105. PubMed: 26023924 MGI: J:233556
Prigge JR; Hoyt TR; Dobrinen E; Capecchi MR; Schmidt EE; Meissner N. 2015. Type I IFNs Act upon Hematopoietic Progenitors To Protect and Maintain Hematopoiesis during Pneumocystis Lung Infection in Mice. J Immunol 195(11):5347-57. PubMed: 26519535 MGI: J:229084
Prigge JR; Wiley JA; Talago EA; Young EM; Johns LL; Kundert JA; Sonsteng KM; Halford WP; Capecchi MR; Schmidt EE. 2013. Nuclear double-fluorescent reporter for in vivo and ex vivo analyses of biological transitions in mouse nuclei. Mamm Genome :. PubMed: 24022199 MGI: J:201735
Prochazka J; Prochazkova M; Du W; Spoutil F; Tureckova J; Hoch R; Shimogori T; Sedlacek R; Rubenstein JL; Wittmann T; Klein OD. 2015. Migration of Founder Epithelial Cells Drives Proper Molar Tooth Positioning and Morphogenesis. Dev Cell 35(6):713-24. PubMed: 26702830 MGI: J:239990
Prunskaite-Hyyrylainen R; Shan J; Railo A; Heinonen KM; Miinalainen I; Yan W; Shen B; Perreault C; Vainio SJ. 2014. Wnt4, a pleiotropic signal for controlling cell polarity, basement membrane integrity, and antimullerian hormone expression during oocyte maturation in the female follicle. FASEB J 28(4):1568-81. PubMed: 24371124 MGI: J:225258
Qiao L; Nishimura T; Shi L; Sessions D; Thrasher A; Trudell JR; Berry GJ; Pearl RG; Kao PN. 2014. Endothelial fate mapping in mice with pulmonary hypertension. Circulation 129(6):692-703. PubMed: 24201301 MGI: J:231994
Ramadas RA; Roche MI; Moon JJ; Ludwig T; Xavier RJ; Medoff BD. 2011. CARMA1 is necessary for optimal T cell responses in a murine model of allergic asthma. J Immunol 187(12):6197-207. PubMed: 22075698 MGI: J:180410
Ramkumar N; Omelchenko T; Silva-Gagliardi NF; McGlade CJ; Wijnholds J; Anderson KV. 2016. Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation. Nat Cell Biol 18(12):1281-1291. PubMed: 27870829 MGI: J:238551
Ramo K; Sugamura K; Craige S; Keaney JF; Davis RJ. 2016. Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development. Elife 5:. PubMed: 27504807 MGI: J:235606
Rattner A; Wang Y; Zhou Y; Williams J; Nathans J. 2014. The role of the hypoxia response in shaping retinal vascular development in the absence of Norrin/Frizzled4 signaling. Invest Ophthalmol Vis Sci 55(12):8614-25. PubMed: 25414188 MGI: J:230295
Ray A; Singh PN; Sohaskey ML; Harland RM; Bandyopadhyay A. 2015. Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation. Development 142(6):1169-79. PubMed: 25758226 MGI: J:238878
Ray HJ; Niswander LA. 2016. Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure. Development 143(7):1192-204. PubMed: 26903501 MGI: J:240158
Ray HJ; Niswander LA. 2016. Dynamic behaviors of the non-neural ectoderm during mammalian cranial neural tube closure. Dev Biol 416(2):279-85. PubMed: 27343896 MGI: J:240368
Ren S; Luo Y; Chen H; Warburton D; Lam HC; Wang LL; Chen P; Henske EP; Shi W. 2016. Inactivation of Tsc2 in Mesoderm-Derived Cells Causes Polycystic Kidney Lesions and Impairs Lung Alveolarization. Am J Pathol 186(12):3261-3272. PubMed: 27768862 MGI: J:238741
Ren X; Ustiyan V; Pradhan A; Cai Y; Havrilak JA; Bolte CS; Shannon JM; Kalin TV; Kalinichenko VV. 2014. FOXF1 transcription factor is required for formation of embryonic vasculature by regulating VEGF signaling in endothelial cells. Circ Res 115(8):709-20. PubMed: 25091710 MGI: J:240455
Reyahi A; Nik AM; Ghiami M; Gritli-Linde A; Ponten F; Johansson BR; Carlsson P. 2015. Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier. Dev Cell 34(1):19-32. PubMed: 26120030 MGI: J:239656
Rinkevich Y; Montoro DT; Contreras-Trujillo H; Harari-Steinberg O; Newman AM; Tsai JM; Lim X; Van-Amerongen R; Bowman A; Januszyk M; Pleniceanu O; Nusse R; Longaker MT; Weissman IL; Dekel B. 2014. In vivo clonal analysis reveals lineage-restricted progenitor characteristics in mammalian kidney development, maintenance, and regeneration. Cell Rep 7(4):1270-83. PubMed: 24835991 MGI: J:211793
Rinkevich Y; Mori T; Sahoo D; Xu PX; Bermingham JR Jr; Weissman IL. 2012. Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs, and their vasculature. Nat Cell Biol 14(12):1251-60. PubMed: 23143399 MGI: J:195251
Rinkevich Y; Walmsley GG; Hu MS; Maan ZN; Newman AM; Drukker M; Januszyk M; Krampitz GW; Gurtner GC; Lorenz HP; Weissman IL; Longaker MT. 2015. Skin fibrosis. Identification and isolation of a dermal lineage with intrinsic fibrogenic potential. Science 348(6232):aaa2151. PubMed: 25883361 MGI: J:222263
Rivera-Gonzalez GC; Shook BA; Andrae J; Holtrup B; Bollag K; Betsholtz C; Rodeheffer MS; Horsley V. 2016. Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis. Cell Stem Cell 19(6):738-751. PubMed: 27746098 MGI: J:240762
Roberts EW; Broz ML; Binnewies M; Headley MB; Nelson AE; Wolf DM; Kaisho T; Bogunovic D; Bhardwaj N; Krummel MF. 2016. Critical Role for CD103(+)/CD141(+) Dendritic Cells Bearing CCR7 for Tumor Antigen Trafficking and Priming of T Cell Immunity in Melanoma. Cancer Cell 30(2):324-36. PubMed: 27424807 MGI: J:234914
Rock JR; Onaitis MW; Rawlins EL; Lu Y; Clark CP; Xue Y; Randell SH; Hogan BL. 2009. Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc Natl Acad Sci U S A 106(31):12771-5. PubMed: 19625615 MGI: J:152012
Rodilla V; Dasti A; Huyghe M; Lafkas D; Laurent C; Reyal F; Fre S. 2015. Luminal progenitors restrict their lineage potential during mammary gland development. PLoS Biol 13(2):e1002069. PubMed: 25688859 MGI: J:232764
Romereim SM; Conoan NH; Chen B; Dudley AT. 2014. A dynamic cell adhesion surface regulates tissue architecture in growth plate cartilage. Development 141(10):2085-95. PubMed: 24764078 MGI: J:220911
Rosen C; Shezen E; Aronovich A; Klionsky YZ; Yaakov Y; Assayag M; Biton IE; Tal O; Shakhar G; Ben-Hur H; Shneider D; Vaknin Z; Sadan O; Evron S; Freud E; Shoseyov D; Wilschanski M; Berkman N; Fibbe WE; Hagin D; Hillel-Karniel C; Krentsis IM; Bachar-Lustig E; Reisner Y. 2015. Preconditioning allows engraftment of mouse and human embryonic lung cells, enabling lung repair in mice. Nat Med 21(8):869-79. PubMed: 26168294 MGI: J:228759
Rudat C; Grieskamp T; Rohr C; Airik R; Wrede C; Hegermann J; Herrmann BG; Schuster-Gossler K; Kispert A. 2014. Upk3b is dispensable for development and integrity of urothelium and mesothelium. PLoS One 9(11):e112112. PubMed: 25389758 MGI: J:225159
Rudat C; Kispert A. 2012. Wt1 and epicardial fate mapping. Circ Res 111(2):165-9. PubMed: 22693350 MGI: J:205035
Rudat C; Norden J; Taketo MM; Kispert A. 2013. Epicardial function of canonical Wnt-, Hedgehog-, Fgfr1/2-, and Pdgfra-signalling. Cardiovasc Res 100(3):411-21. PubMed: 24000064 MGI: J:219551
Rusielewicz T; Nam J; Damanakis E; John GR; Raine CS; Melendez-Vasquez CV. 2014. Accelerated repair of demyelinated CNS lesions in the absence of non-muscle myosin IIB. Glia 62(4):580-91. PubMed: 24470341 MGI: J:207481
Sachs N; Claessen N; Aten J; Kreft M; Teske GJ; Koeman A; Zuurbier CJ; Janssen H; Sonnenberg A. 2012. Blood pressure influences end-stage renal disease of Cd151 knockout mice. J Clin Invest 122(1):348-58. PubMed: 22201679 MGI: J:184392
Sale S; Lafkas D; Artavanis-Tsakonas S. 2013. Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages. Nat Cell Biol 15(5):451-60. PubMed: 23604318 MGI: J:198503
Samanta J; Grund EM; Silva HM; Lafaille JJ; Fishell G; Salzer JL. 2015. Inhibition of Gli1 mobilizes endogenous neural stem cells for remyelination. Nature 526(7573):448-52. PubMed: 26416758 MGI: J:226772
Sambasivan R; Comai G; Le Roux I; Gomes D; Konge J; Dumas G; Cimper C; Tajbakhsh S. 2013. Embryonic founders of adult muscle stem cells are primed by the determination gene Mrf4. Dev Biol 381(1):241-55. PubMed: 23623977 MGI: J:200727
Sanchez-Gurmaches J; Guertin DA. 2014. Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed. Nat Commun 5:4099. PubMed: 24942009 MGI: J:238822
Sanchez-Gurmaches J; Hsiao WY; Guertin DA. 2015. Highly selective in vivo labeling of subcutaneous white adipocyte precursors with Prx1-Cre. Stem Cell Reports 4(4):541-50. PubMed: 25801508 MGI: J:232971
Santos R; Kawauchi S; Jacobs RE; Lopez-Burks ME; Choi H; Wikenheiser J; Hallgrimsson B; Jamniczky HA; Fraser SE; Lander AD; Calof AL. 2016. Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects. PLoS Biol 14(9):e2000197. PubMed: 27606604 MGI: J:236978
Schell C; Kretz O; Liang W; Kiefer B; Schneider S; Sellung D; Bork T; Leiber C; Ruegg MA; Mallidis C; Schlatt S; Mayerhofer A; Huber TB; Grahammer F. 2016. The Rapamycin-Sensitive Complex of Mammalian Target of Rapamycin Is Essential to Maintain Male Fertility. Am J Pathol 186(2):324-36. PubMed: 26683665 MGI: J:229682
Schjerven H; Ayongaba EF; Aghajanirefah A; McLaughlin J; Cheng D; Geng H; Boyd JR; Eggesbo LM; Lindeman I; Heath JL; Park E; Witte ON; Smale ST; Frietze S; Muschen M. 2017. Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL. J Exp Med 214(3):793-814. PubMed: 28190001 MGI: J:241538
Schonhuber N; Seidler B; Schuck K; Veltkamp C; Schachtler C; Zukowska M; Eser S; Feyerabend TB; Paul MC; Eser P; Klein S; Lowy AM; Banerjee R; Yang F; Lee CL; Moding EJ; Kirsch DG; Scheideler A; Alessi DR; Varela I; Bradley A; Kind A; Schnieke AE; Rodewald HR; Rad R; Schmid RM; Schneider G; Saur D. 2014. A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer. Nat Med 20(11):1340-7. PubMed: 25326799 MGI: J:218155
Sennett R; Rezza A; Dauber KL; Clavel C; Rendl M. 2014. Cxcr4 is transiently expressed in both epithelial and mesenchymal compartments of nascent hair follicles but is not required for follicle formation. Exp Dermatol 23(10):748-50. PubMed: 25066162 MGI: J:215784
Sequeira-Lopez ML; Nagalakshmi VK; Li M; Sigmund CD; Gomez RA. 2015. Vascular versus tubular renin: role in kidney development. Am J Physiol Regul Integr Comp Physiol 309(6):R650-7. PubMed: 26246508 MGI: J:227281
Serresi M; Gargiulo G; Proost N; Siteur B; Cesaroni M; Koppens M; Xie H; Sutherland KD; Hulsman D; Citterio E; Orkin S; Berns A; van Lohuizen M. 2016. Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer. Cancer Cell 29(1):17-31. PubMed: 26766588 MGI: J:231322
Sewduth RN; Jaspard-Vinassa B; Peghaire C; Guillabert A; Franzl N; Larrieu-Lahargue F; Moreau C; Fruttiger M; Dufourcq P; Couffinhal T; Duplaa C. 2014. The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling. Nat Commun 5:4832. PubMed: 25198863 MGI: J:222522
Shaner NC; Campbell RE; Steinbach PA; Giepmans BN; Palmer AE; Tsien RY. 2004. Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol 22(12):1567-72. PubMed: 15558047 MGI: J:123053
Shao L; Zhou HJ; Zhang H; Qin L; Hwa J; Yun Z; Ji W; Min W. 2015. SENP1-mediated NEMO deSUMOylation in adipocytes limits inflammatory responses and type-1 diabetes progression. Nat Commun 6:8917. PubMed: 26596471 MGI: J:228009
Sheikh AQ; Lighthouse JK; Greif DM. 2014. Recapitulation of developing artery muscularization in pulmonary hypertension. Cell Rep 6(5):809-17. PubMed: 24582963 MGI: J:211834
Sheikh AQ; Misra A; Rosas IO; Adams RH; Greif DM. 2015. Smooth muscle cell progenitors are primed to muscularize in pulmonary hypertension. Sci Transl Med 7(308):308ra159. PubMed: 26446956 MGI: J:234068
Sheikh BN; Bechtel-Walz W; Lucci J; Karpiuk O; Hild I; Hartleben B; Vornweg J; Helmstadter M; Sahyoun AH; Bhardwaj V; Stehle T; Diehl S; Kretz O; Voss AK; Thomas T; Manke T; Huber TB; Akhtar A. 2016. MOF maintains transcriptional programs regulating cellular stress response. Oncogene 35(21):2698-710. PubMed: 26387537 MGI: J:234312
Shetty AS; Godbole G; Maheshwari U; Padmanabhan H; Chaudhary R; Muralidharan B; Hou PS; Monuki ES; Kuo HC; Rema V; Tole S. 2013. Lhx2 regulates a cortex-specific mechanism for barrel formation. Proc Natl Acad Sci U S A 110(50):E4913-21. PubMed: 24262147 MGI: J:205196
Shetty SK; Tiwari N; Marudamuthu AS; Puthusseri B; Bhandary YP; Fu J; Levin J; Idell S; Shetty S. 2017. p53 and miR-34a Feedback Promotes Lung Epithelial Injury and Pulmonary Fibrosis. Am J Pathol 187(5):1016-1034. PubMed: 28273432 MGI: J:241943
Shi F; Hu L; Edge AS. 2013. Generation of hair cells in neonatal mice by beta-catenin overexpression in Lgr5-positive cochlear progenitors. Proc Natl Acad Sci U S A 110(34):13851-6. PubMed: 23918377 MGI: J:200672
Shi G; DiRenzo D; Qu C; Barney D; Miley D; Konieczny SF. 2013. Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia. Oncogene 32(15):1950-8. PubMed: 22665051 MGI: J:197233
Shi Y; Tu Y; De Maria A; Mecham RP; Bassnett S. 2013. Development, composition, and structural arrangements of the ciliary zonule of the mouse. Invest Ophthalmol Vis Sci 54(4):2504-15. PubMed: 23493297 MGI: J:214897
Shibata S; Miwa T; Wu HH; Levitt P; Ohyama T. 2016. Hepatocyte Growth Factor-c-MET Signaling Mediates the Development of Nonsensory Structures of the Mammalian Cochlea and Hearing. J Neurosci 36(31):8200-9. PubMed: 27488639 MGI: J:234621
Shin K; Lee J; Guo N; Kim J; Lim A; Qu L; Mysorekar IU; Beachy PA. 2011. Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder. Nature 472(7341):110-4. PubMed: 21389986 MGI: J:170991
Shin K; Lim A; Odegaard JI; Honeycutt JD; Kawano S; Hsieh MH; Beachy PA. 2014. Cellular origin of bladder neoplasia and tissue dynamics of its progression to invasive carcinoma. Nat Cell Biol 16(5):469-78. PubMed: 24747439 MGI: J:218864
Shiota C; Prasadan K; Guo P; El-Gohary Y; Wiersch J; Xiao X; Esni F; Gittes GK. 2013. alpha-Cells are dispensable in postnatal morphogenesis and maturation of mouse pancreatic islets. Am J Physiol Endocrinol Metab 305(8):E1030-40. PubMed: 23982158 MGI: J:203933
Shirakawa T; Yaman-Deveci R; Tomizawa S; Kamizato Y; Nakajima K; Sone H; Sato Y; Sharif J; Yamashita A; Takada-Horisawa Y; Yoshida S; Ura K; Muto M; Koseki H; Suda T; Ohbo K. 2013. An epigenetic switch is crucial for spermatogonia to exit the undifferentiated state toward a Kit-positive identity. Development 140(17):3565-76. PubMed: 23903187 MGI: J:199286
Shiratori H; Yashiro K; Iwai N; Oki S; Minegishi K; Ikawa Y; Kanata K; Hamada H. 2014. Self-regulated left-right asymmetric expression of Pitx2c in the developing mouse limb. Dev Biol 395(2):331-41. PubMed: 25224222 MGI: J:216504
Shook B; Xiao E; Kumamoto Y; Iwasaki A; Horsley V. 2016. CD301b+ Macrophages Are Essential for Effective Skin Wound Healing. J Invest Dermatol 136(9):1885-91. PubMed: 27287183 MGI: J:235071
Shore AN; Chang CH; Kwon OJ; Weston MC; Zhang M; Xin L; Rosen JM. 2016. PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland. Dev Biol 409(1):202-17. PubMed: 26526198 MGI: J:228789
Smith AA; Li J; Liu B; Hunter D; Pyles M; Gillette M; Dhamdhere GR; Abo A; Oro A; Helms JA. 2016. Activating Hair Follicle Stem Cells via R-spondin2 to Stimulate Hair Growth. J Invest Dermatol 136(8):1549-58. PubMed: 27109869 MGI: J:235025
Snedeker J; Schock EN; Struve JN; Chang CF; Cionni M; Tran PV; Brugmann SA; Stottmann RW. 2017. Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development. PLoS One 12(3):e0173258. PubMed: 28291836 MGI: J:241366
Snitow M; Lu M; Cheng L; Zhou S; Morrisey EE. 2016. Ezh2 restricts the smooth muscle lineage during mouse lung mesothelial development. Development 143(20):3733-3741. PubMed: 27578795 MGI: J:240484
Snowball J; Ambalavanan M; Whitsett J; Sinner D. 2015. Endodermal Wnt signaling is required for tracheal cartilage formation. Dev Biol 405(1):56-70. PubMed: 26093309 MGI: J:225740
Snyder CS; Harrington AR; Kaushal S; Mose E; Lowy AM; Hoffman RM; Bouvet M. 2013. A dual-color genetically engineered mouse model for multispectral imaging of the pancreatic microenvironment. Pancreas 42(6):952-8. PubMed: 23648841 MGI: J:232009
Song H; Yao E; Lin C; Gacayan R; Chen MH; Chuang PT. 2012. Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis. Proc Natl Acad Sci U S A 109(43):17531-6. PubMed: 23047698 MGI: J:190366
Song L; Liu M; Ono N; Bringhurst FR; Kronenberg HM; Guo J. 2012. Loss of wnt/beta-catenin signaling causes cell fate shift of preosteoblasts from osteoblasts to adipocytes. J Bone Miner Res 27(11):2344-58. PubMed: 22729939 MGI: J:231717
Song R; Hennig GW; Wu Q; Jose C; Zheng H; Yan W. 2011. Male germ cells express abundant endogenous siRNAs. Proc Natl Acad Sci U S A 108(32):13159-64. PubMed: 21788498 MGI: J:175627
Soudja SM; Ruiz AL; Marie JC; Lauvau G. 2012. Inflammatory Monocytes Activate Memory CD8(+) T and Innate NK Lymphocytes Independent of Cognate Antigen during Microbial Pathogen Invasion. Immunity 37(3):549-62. PubMed: 22940097 MGI: J:187687
Srinivasan RS; Escobedo N; Yang Y; Interiano A; Dillard ME; Finkelstein D; Mukatira S; Gil HJ; Nurmi H; Alitalo K; Oliver G. 2014. The Prox1-Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors. Genes Dev 28(19):2175-87. PubMed: 25274728 MGI: J:217439
Srinivasan RS; Oliver G. 2011. Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves. Genes Dev 25(20):2187-97. PubMed: 22012621 MGI: J:177488
Stahl A; Joyal JS; Chen J; Sapieha P; Juan AM; Hatton CJ; Pei DT; Hurst CG; Seaward MR; Krah NM; Dennison RJ; Greene ER; Boscolo E; Panigrahy D; Smith LE. 2012. SOCS3 is an endogenous inhibitor of pathologic angiogenesis. Blood 120(14):2925-9. PubMed: 22791286 MGI: J:189163
Stanczuk L; Martinez-Corral I; Ulvmar MH; Zhang Y; Lavina B; Fruttiger M; Adams RH; Saur D; Betsholtz C; Ortega S; Alitalo K; Graupera M; Makinen T. 2015. cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels. Cell Rep :. PubMed: 25772358 MGI: J:228184
Straessler KM; Jones KB; Hu H; Jin H; van de Rijn M; Capecchi MR. 2013. Modeling clear cell sarcomagenesis in the mouse: cell of origin differentiation state impacts tumor characteristics. Cancer Cell 23(2):215-27. PubMed: 23410975 MGI: J:194308
Stuelsatz P; Keire P; Almuly R; Yablonka-Reuveni Z. 2012. A contemporary atlas of the mouse diaphragm: myogenicity, vascularity, and the Pax3 connection. J Histochem Cytochem 60(9):638-57. PubMed: 22723526 MGI: J:193734
Stuelsatz P; Shearer A; Li Y; Muir LA; Ieronimakis N; Shen QW; Kirillova I; Yablonka-Reuveni Z. 2015. Extraocular muscle satellite cells are high performance myo-engines retaining efficient regenerative capacity in dystrophin deficiency. Dev Biol 397(1):31-44. PubMed: 25236433 MGI: J:218053
Stuelsatz P; Shearer A; Yablonka-Reuveni Z. 2014. Ancestral Myf5 gene activity in periocular connective tissue identifies a subset of fibro/adipogenic progenitors but does not connote a myogenic origin. Dev Biol 385(2):366-79. PubMed: 23969310 MGI: J:205346
Su H; Marcheva B; Meng S; Liang FA; Kohsaka A; Kobayashi Y; Xu AW; Bass J; Wang X. 2010. Gamma-protocadherins regulate the functional integrity of hypothalamic feeding circuitry in mice. Dev Biol 339(1):38-50. PubMed: 20025866 MGI: J:157958
Suga H; Rennert RC; Rodrigues M; Sorkin M; Glotzbach JP; Januszyk M; Fujiwara T; Longaker MT; Gurtner GC. 2014. Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing. Stem Cells 32(5):1347-60. PubMed: 24446236 MGI: J:211214
Sutherland KD; Proost N; Brouns I; Adriaensen D; Song JY; Berns A. 2011. Cell of origin of small cell lung cancer: inactivation of Trp53 and rb1 in distinct cell types of adult mouse lung. Cancer Cell 19(6):754-64. PubMed: 21665149 MGI: J:173560
Suvorova ES; Lucas O; Weisend CM; Rollins MF; Merrill GF; Capecchi MR; Schmidt EE. 2009. Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes. PLoS One 4(7):e6158. PubMed: 19584930 MGI: J:151615
Szabat M; Page MM; Panzhinskiy E; Skovso S; Mojibian M; Fernandez-Tajes J; Bruin JE; Bround MJ; Lee JT; Xu EE; Taghizadeh F; O'Dwyer S; van de Bunt M; Moon KM; Sinha S; Han J; Fan Y; Lynn FC; Trucco M; Borchers CH; Foster LJ; Nislow C; Kieffer TJ; Johnson JD. 2016. Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces beta Cell Proliferation. Cell Metab 23(1):179-93. PubMed: 26626461 MGI: J:232741
Tabler JM; Barrell WB; Szabo-Rogers HL; Healy C; Yeung Y; Perdiguero EG; Schulz C; Yannakoudakis BZ; Mesbahi A; Wlodarczyk B; Geissmann F; Finnell RH; Wallingford JB; Liu KJ. 2013. Fuz Mutant Mice Reveal Shared Mechanisms between Ciliopathies and FGF-Related Syndromes. Dev Cell 25(6):623-35. PubMed: 23806618 MGI: J:198631
Tabler JM; Rice CP; Liu KJ; Wallingford JB. 2016. A novel ciliopathic skull defect arising from excess neural crest. Dev Biol 417(1):4-10. PubMed: 27395007 MGI: J:235627
Tabler JM; Rigney MM; Berman GJ; Gopalakrishnan S; Heude E; Al-Lami HA; Yannakoudiadkis BZ; Fitch RD; Carter C; Vokes S; Liu KJ; Tajbakhsh S; Egnor SR; Wallingford JB. 2017. Cilia-mediated Hedgehog signaling controls form and function in the mammalian larynx. Elife 6:. PubMed: 28177282 MGI: J:241145
Tadokoro T; Gao X; Hong CC; Hotten D; Hogan BL. 2016. BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors. Development 143(5):764-73. PubMed: 26811382 MGI: J:240088
Takeda N; Jain R; Leboeuf MR; Padmanabhan A; Wang Q; Li L; Lu MM; Millar SE; Epstein JA. 2013. Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells. Development 140(8):1655-64. PubMed: 23487314 MGI: J:195123
Takeda N; Jain R; Leboeuf MR; Wang Q; Lu MM; Epstein JA. 2011. Interconversion Between Intestinal Stem Cell Populations in Distinct Niches. Science :. PubMed: 22075725 MGI: J:178296
Talbot S; Abdulnour RE; Burkett PR; Lee S; Cronin SJ; Pascal MA; Laedermann C; Foster SL; Tran JV; Lai N; Chiu IM; Ghasemlou N; DiBiase M; Roberson D; Von Hehn C; Agac B; Haworth O; Seki H; Penninger JM; Kuchroo VK; Bean BP; Levy BD; Woolf CJ. 2015. Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation. Neuron 87(2):341-54. PubMed: 26119026 MGI: J:227431
Tarlow BD; Pelz C; Naugler WE; Wakefield L; Wilson EM; Finegold MJ; Grompe M. 2014. Bipotential adult liver progenitors are derived from chronically injured mature hepatocytes. Cell Stem Cell 15(5):605-18. PubMed: 25312494 MGI: J:218537
Tarlungeanu DC; Deliu E; Dotter CP; Kara M; Janiesch PC; Scalise M; Galluccio M; Tesulov M; Morelli E; Sonmez FM; Bilguvar K; Ohgaki R; Kanai Y; Johansen A; Esharif S; Ben-Omran T; Topcu M; Schlessinger A; Indiveri C; Duncan KE; Caglayan AO; Gunel M; Gleeson JG; Novarino G. 2016. Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder. Cell 167(6):1481-1494.e18. PubMed: 27912058 MGI: J:238065
Teisanu RM; Chen H; Matsumoto K; McQualter JL; Potts E; Foster WM; Bertoncello I; Stripp BR. 2011. Functional analysis of two distinct bronchiolar progenitors during lung injury and repair. Am J Respir Cell Mol Biol 44(6):794-803. PubMed: 20656948 MGI: J:185030
Terakawa J; Rocchi A; Serna VA; Bottinger EP; Graff JM; Kurita T. 2016. FGFR2IIIb-MAPK Activity Is Required for Epithelial Cell Fate Decision in the Lower Mullerian Duct. Mol Endocrinol 30(7):783-95. PubMed: 27164167 MGI: J:234158
Tevosian SG; Jimenez E; Hatch HM; Jiang T; Morse DA; Fox SC; Padua MB. 2015. Adrenal Development in Mice Requires GATA4 and GATA6 Transcription Factors. Endocrinology 156(7):2503-17. PubMed: 25933105 MGI: J:224628
Thompson NJ; Sengelaub DR; English AW. 2014. Enhancement of peripheral nerve regeneration due to treadmill training and electrical stimulation is dependent on androgen receptor signaling. Dev Neurobiol 74(5):531-40. PubMed: 24293191 MGI: J:241818
Tian X; Hu T; Zhang H; He L; Huang X; Liu Q; Yu W; He L; Yang Z; Yan Y; Yang X; Zhong TP; Pu WT; Zhou B. 2014. Vessel formation. De novo formation of a distinct coronary vascular population in neonatal heart. Science 345(6192):90-4. PubMed: 24994653 MGI: J:212075
Tian X; Hu T; Zhang H; He L; Huang X; Liu Q; Yu W; He L; Yang Z; Zhang Z; Zhong TP; Yang X; Yang Z; Yan Y; Baldini A; Sun Y; Lu J; Schwartz RJ; Evans SM; Gittenberger-de Groot AC; Red-Horse K; Zhou B. 2013. Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries. Cell Res 23(9):1075-90. PubMed: 23797856 MGI: J:220957
Toh B; Wang X; Keeble J; Sim WJ; Khoo K; Wong WC; Kato M; Prevost-Blondel A; Thiery JP; Abastado JP. 2011. Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cells infiltrating the primary tumor. PLoS Biol 9(9):e1001162. PubMed: 21980263 MGI: J:184038
Tong MH; Yang QE; Davis JC; Griswold MD. 2013. Retinol dehydrogenase 10 is indispensible for spermatogenesis in juvenile males. Proc Natl Acad Sci U S A 110(2):543-8. PubMed: 23267101 MGI: J:193281
Tong PL; Roediger B; Kolesnikoff N; Biro M; Tay SS; Jain R; Shaw LE; Grimbaldeston MA; Weninger W. 2015. The skin immune atlas: three-dimensional analysis of cutaneous leukocyte subsets by multiphoton microscopy. J Invest Dermatol 135(1):84-93. PubMed: 25007044 MGI: J:216200
Trembley MA; Velasquez LS; de Mesy Bentley KL; Small EM. 2015. Myocardin-related transcription factors control the motility of epicardium-derived cells and the maturation of coronary vessels. Development 142(1):21-30. PubMed: 25516967 MGI: J:217680
Troeger JS; Mederacke I; Gwak GY; Dapito DH; Mu X; Hsu CC; Pradere JP; Friedman RA; Schwabe RF. 2012. Deactivation of hepatic stellate cells during liver fibrosis resolution in mice. Gastroenterology 143(4):1073-83.e22. PubMed: 22750464 MGI: J:231716
Trowe MO; Maier H; Petry M; Schweizer M; Schuster-Gossler K; Kispert A. 2011. Impaired stria vascularis integrity upon loss of E-cadherin in basal cells. Dev Biol 359(1):95-107. PubMed: 21925491 MGI: J:178162
Trowe MO; Zhao L; Weiss AC; Christoffels V; Epstein DJ; Kispert A. 2013. Inhibition of Sox2-dependent activation of Shh in the ventral diencephalon by Tbx3 is required for formation of the neurohypophysis. Development 140(11):2299-309. PubMed: 23674600 MGI: J:198684
Tuduri E; Denroche HC; Kara JA; Asadi A; Fox JK; Kieffer TJ. 2014. Partial ablation of leptin signaling in mouse pancreatic alpha-cells does not alter either glucose or lipid homeostasis. Am J Physiol Endocrinol Metab 306(7):E748-55. PubMed: 24473435 MGI: J:211592
Turcatel G; Rubin N; Menke DB; Martin G; Shi W; Warburton D. 2013. Lung mesenchymal expression of Sox9 plays a critical role in tracheal development. BMC Biol 11:117. PubMed: 24274029 MGI: J:225175
Turner CJ; Badu-Nkansah K; Crowley D; van der Flier A; Hynes RO. 2015. alpha5 and alphav integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo. Development 142(4):797-808. PubMed: 25670798 MGI: J:218158
Turner CJ; Badu-Nkansah K; Crowley D; van der Flier A; Hynes RO. 2014. Integrin-alpha5beta1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation. Dev Biol 392(2):381-92. PubMed: 24858485 MGI: J:215000
Ucar O; Li K; Dvornikov D; Kreutz C; Timmer J; Matt S; Brenner L; Smedley C; Travis MA; Hofmann TG; Klingmuller U; Kyewski B. 2016. A Thymic Epithelial Stem Cell Pool Persists throughout Ontogeny and Is Modulated by TGF-beta. Cell Rep 17(2):448-457. PubMed: 27705793 MGI: J:240661
Ueki Y; Ramirez G; Salcedo E; Stabio ME; Lefcort F. 2016. Loss of Ikbkap Causes Slow, Progressive Retinal Degeneration in a Mouse Model of Familial Dysautonomia. eNeuro 3(5):. PubMed: 27699209 MGI: J:237775
Ueki Y; Wilken MS; Cox KE; Chipman LB; Bermingham-McDonogh O; Reh TA. 2015. A transient wave of BMP signaling in the retina is necessary for Muller glial differentiation. Development 142(3):533-43. PubMed: 25605781 MGI: J:238901
Van Batavia J; Yamany T; Molotkov A; Dan H; Mansukhani M; Batourina E; Schneider K; Oyon D; Dunlop M; Wu XR; Cordon-Cardo C; Mendelsohn C. 2014. Bladder cancers arise from distinct urothelial sub-populations. Nat Cell Biol 16(10):982-91, 1-5. PubMed: 25218638 MGI: J:217711
Vassilev VS; Mandai M; Yonemura S; Takeichi M. 2012. Loss of N-cadherin from the endothelium causes stromal edema and epithelial dysgenesis in the mouse cornea. Invest Ophthalmol Vis Sci 53(11):7183-93. PubMed: 22991418 MGI: J:214277
Vaughan AE; Brumwell AN; Xi Y; Gotts JE; Brownfield DG; Treutlein B; Tan K; Tan V; Liu FC; Looney MR; Matthay MA; Rock JR; Chapman HA. 2015. Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury. Nature 517(7536):621-5. PubMed: 25533958 MGI: J:218377
Venkatareddy M; Verma R; Kalinowski A; Patel SR; Shisheva A; Garg P. 2016. Distinct Requirements for Vacuolar Protein Sorting 34 Downstream Effector Phosphatidylinositol 3-Phosphate 5-Kinase in Podocytes Versus Proximal Tubular Cells. J Am Soc Nephrol :. PubMed: 26825532 MGI: J:232994
Visbal AP; LaMarca HL; Villanueva H; Toneff MJ; Li Y; Rosen JM; Lewis MT. 2011. Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened. Dev Biol 352(1):116-27. PubMed: 21276786 MGI: J:171474
Vishvanath L; MacPherson KA; Hepler C; Wang QA; Shao M; Spurgin SB; Wang MY; Kusminski CM; Morley TS; Gupta RK. 2015. Pdgfrbeta Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat-Diet Feeding and Prolonged Cold Exposure in Adult Mice. Cell Metab :. PubMed: 26626462 MGI: J:226969
Volz KS; Jacobs AH; Chen HI; Poduri A; McKay AS; Riordan DP; Kofler N; Kitajewski J; Weissman I; Red-Horse K. 2015. Pericytes are progenitors for coronary artery smooth muscle. Elife 4:. PubMed: 26479710 MGI: J:229606
Wahl SE; McLane LE; Bercury KK; Macklin WB; Wood TL. 2014. Mammalian target of rapamycin promotes oligodendrocyte differentiation, initiation and extent of CNS myelination. J Neurosci 34(13):4453-65. PubMed: 24671992 MGI: J:210457
Wang B; Zhao L; Fish M; Logan CY; Nusse R. 2015. Self-renewing diploid Axin2(+) cells fuel homeostatic renewal of the liver. Nature 524(7564):180-5. PubMed: 26245375 MGI: J:225792
Wang D; Cai C; Dong X; Yu QC; Zhang XO; Yang L; Zeng YA. 2015. Identification of multipotent mammary stem cells by protein C receptor expression. Nature 517(7532):81-4. PubMed: 25327250 MGI: J:217483
Wang G; Lu X; Dey P; Deng P; Wu CC; Jiang S; Fang Z; Zhao K; Konaparthi R; Hua S; Zhang J; Li-Ning-Tapia EM; Kapoor A; Wu CJ; Patel NB; Guo Z; Ramamoorthy V; Tieu TN; Heffernan T; Zhao D; Shang X; Khadka S; Hou P; Hu B; Jin EJ; Yao W; Pan X; Ding Z; Shi Y; Li L; Chang Q; Troncoso P; Logothetis CJ; McArthur MJ; Chin L; Wang YA; DePinho RA. 2016. Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression. Cancer Discov 6(1):80-95. PubMed: 26701088 MGI: J:232811
Wang H; Graham I; Hastings R; Gunewardena S; Brinkmeier ML; Conn PM; Camper SA; Kumar TR. 2015. Gonadotrope-specific Deletion of Dicer Results in Severely Suppressed Gonadotropins and Fertility Defects. J Biol Chem 290(5):2699-714. PubMed: 25525274 MGI: J:217871
Wang JH; Wang QJ; Wang C; Reinholt B; Grant AL; Gerrard DE; Kuang S. 2015. Heterogeneous activation of a slow myosin gene in proliferating myoblasts and differentiated single myofibers. Dev Biol 402(1):72-80. PubMed: 25794679 MGI: J:222436
Wang L; Benedito R; Bixel MG; Zeuschner D; Stehling M; Savendahl L; Haigh JJ; Snippert H; Clevers H; Breier G; Kiefer F; Adams RH. 2013. Identification of a clonally expanding haematopoietic compartment in bone marrow. EMBO J 32(2):219-30. PubMed: 23188081 MGI: J:193124
Wang S; Sengel C; Emerson MM; Cepko CL. 2014. A gene regulatory network controls the binary fate decision of rod and bipolar cells in the vertebrate retina. Dev Cell 30(5):513-27. PubMed: 25155555 MGI: J:214806
Wang W; Kissig M; Rajakumari S; Huang L; Lim HW; Won KJ; Seale P. 2014. Ebf2 is a selective marker of brown and beige adipogenic precursor cells. Proc Natl Acad Sci U S A 111(40):14466-71. PubMed: 25197048 MGI: J:216370
Wang X; Wang Y; Snitow ME; Stewart KM; Li S; Lu M; Morrisey EE. 2016. Expression of histone deacetylase 3 instructs alveolar type I cell differentiation by regulating a Wnt signaling niche in the lung. Dev Biol 414(2):161-9. PubMed: 27141870 MGI: J:233746
Watanabe K; Villarreal-Ponce A; Sun P; Salmans ML; Fallahi M; Andersen B; Dai X. 2014. Mammary morphogenesis and regeneration require the inhibition of EMT at terminal end buds by Ovol2 transcriptional repressor. Dev Cell 29(1):59-74. PubMed: 24735879 MGI: J:211311
Weinl C; Riehle H; Park D; Stritt C; Beck S; Huber G; Wolburg H; Olson EN; Seeliger MW; Adams RH; Nordheim A. 2013. Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae. J Clin Invest 123(5):2193-206. PubMed: 23563308 MGI: J:201346
Weisend CM; Kundert JA; Suvorova ES; Prigge JR; Schmidt EE. 2009. Cre activity in fetal albCre mouse hepatocytes: Utility for developmental studies. Genesis 47(12):789-92. PubMed: 19830819 MGI: J:156028
Weiss AC; Airik R; Bohnenpoll T; Greulich F; Foik A; Trowe MO; Rudat C; Costantini F; Adams RH; Kispert A. 2014. Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme. Development 141(17):3420-30. PubMed: 25139858 MGI: J:214811
Wessels A; van den Hoff MJ; Adamo RF; Phelps AL; Lockhart MM; Sauls K; Briggs LE; Norris RA; van Wijk B; Perez-Pomares JM; Dettman RW; Burch JB. 2012. Epicardially derived fibroblasts preferentially contribute to the parietal leaflets of the atrioventricular valves in the murine heart. Dev Biol 366(2):111-24. PubMed: 22546693 MGI: J:185565
Wilhelm JC; Xu M; Cucoranu D; Chmielewski S; Holmes T; Lau KS; Bassell GJ; English AW. 2012. Cooperative roles of BDNF expression in neurons and Schwann cells are modulated by exercise to facilitate nerve regeneration. J Neurosci 32(14):5002-9. PubMed: 22492055 MGI: J:184131
Wirrig EE; Gomez MV; Hinton RB; Yutzey KE. 2015. COX2 inhibition reduces aortic valve calcification in vivo. Arterioscler Thromb Vasc Biol 35(4):938-47. PubMed: 25722432 MGI: J:241336
Wood MA; Acharya A; Finco I; Swonger JM; Elston MJ; Tallquist MD; Hammer GD. 2013. Fetal adrenal capsular cells serve as progenitor cells for steroidogenic and stromal adrenocortical cell lineages in M. musculus. Development 140(22):4522-32. PubMed: 24131628 MGI: J:204972
Wu B; Zhou B; Wang Y; Cheng HL; Hang CT; Pu WT; Chang CP; Zhou B. 2010. Inducible cardiomyocyte-specific gene disruption directed by the rat Tnnt2 promoter in the mouse. Genesis 48(1):63-72. PubMed: 20014345 MGI: J:157454
Wu J; Zheng C; Wang X; Yun S; Zhao Y; Liu L; Lu Y; Ye Y; Zhu X; Zhang C; Shi S; Liu Z. 2015. MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes. J Clin Invest 125(11):4091-106. PubMed: 26436650 MGI: J:227487
Wu Q; Song R; Ortogero N; Zheng H; Evanoff R; Small CL; Griswold MD; Namekawa SH; Royo H; Turner JM; Yan W. 2012. The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis. J Biol Chem 287(30):25173-90. PubMed: 22665486 MGI: J:188848
Wu R; Li H; Zhai L; Zou X; Meng J; Zhong R; Li C; Wang H; Zhang Y; Zhu D. 2015. MicroRNA-431 accelerates muscle regeneration and ameliorates muscular dystrophy by targeting Pax7 in mice. Nat Commun 6:7713. PubMed: 26151913 MGI: J:224368
Xiao X; Gaffar I; Guo P; Wiersch J; Fischbach S; Peirish L; Song Z; El-Gohary Y; Prasadan K; Shiota C; Gittes GK. 2014. M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7. Proc Natl Acad Sci U S A 111(13):E1211-20. PubMed: 24639504 MGI: J:207370
Xie S; Xu J; Ma W; Liu Q; Han J; Yao G; Huang X; Zhang Y. 2013. Lcn5 promoter directs the region-specific expression of cre recombinase in caput epididymidis of transgenic mice. Biol Reprod 88(3):71. PubMed: 23349236 MGI: J:194481
Xu B; Yang L; Hinton BT. 2013. The Role of fibroblast growth factor receptor substrate 2 (FRS2) in the regulation of two activity levels of the components of the extracellular signal-regulated kinase (ERK) pathway in the mouse epididymis. Biol Reprod 89(2):48. PubMed: 23782834 MGI: J:203744
Xu EE; Krentz NA; Tan S; Chow SZ; Tang M; Nian C; Lynn FC. 2015. SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models. Diabetologia 58(5):1013-23. PubMed: 25652387 MGI: J:220744
Xu M; Horrell J; Snitow M; Cui J; Gochnauer H; Syrett CM; Kallish S; Seykora JT; Liu F; Gaillard D; Katz JP; Kaestner KH; Levin B; Mansfield C; Douglas JE; Cowart BJ; Tordoff M; Liu F; Zhu X; Barlow LA; Rubin AI; McGrath JA; Morrisey EE; Chu EY; Millar SE. 2017. WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation. Nat Commun 8:15397. PubMed: 28589954 MGI: J:242196
Xu Y; Evaristo C; Alegre ML; Gurbuxani S; Kee BL. 2015. Analysis of GzmbCre as a Model System for Gene Deletion in the Natural Killer Cell Lineage. PLoS One 10(4):e0125211. PubMed: 25923440 MGI: J:220371
Yang J; Dominguez B; de Winter F; Gould TW; Eriksson JE; Lee KF. 2011. Nestin negatively regulates postsynaptic differentiation of the neuromuscular synapse. Nat Neurosci 14(3):324-30. PubMed: 21278733 MGI: J:170107
Yang J; Kantrow S; Sai J; Hawkins OE; Boothby M; Ayers GD; Young ED; Demicco EG; Lazar AJ; Lev D; Richmond A. 2012. Ikk4a/Arf inactivation with activation of the NF-kappaB/IL-6 pathway is sufficient to drive the development and growth of angiosarcoma. Cancer Res 72(18):4682-95. PubMed: 22836752 MGI: J:191329
Yazji I; Sodhi CP; Lee EK; Good M; Egan CE; Afrazi A; Neal MD; Jia H; Lin J; Ma C; Branca MF; Prindle T; Richardson WM; Ozolek J; Billiar TR; Binion DG; Gladwin MT; Hackam DJ. 2013. Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling. Proc Natl Acad Sci U S A 110(23):9451-6. PubMed: 23650378 MGI: J:197450
Yee M; Buczynski BW; O'Reilly MA. 2014. Neonatal hyperoxia stimulates the expansion of alveolar epithelial type II cells. Am J Respir Cell Mol Biol 50(4):757-66. PubMed: 24188066 MGI: J:232090
Yu K; Karuppaiah K; Ornitz DM. 2015. Mesenchymal fibroblast growth factor receptor signaling regulates palatal shelf elevation during secondary palate formation. Dev Dyn 244(11):1427-38. PubMed: 26250517 MGI: J:226187
Yu YR; You LR; Yan YT; Chen CM. 2014. Role of OVCA1/DPH1 in craniofacial abnormalities of Miller-Dieker syndrome. Hum Mol Genet 23(21):5579-96. PubMed: 24895408 MGI: J:214744
Zandvakili I; Davis AK; Hu G; Zheng Y. 2015. Loss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice. PLoS One 10(6):e0127923. PubMed: 26030593 MGI: J:237723
Zeng L; Cai C; Li S; Wang W; Li Y; Chen J; Zhu X; Zeng YA. 2016. Essential Roles of Cyclin Y-Like 1 and Cyclin Y in Dividing Wnt-Responsive Mammary Stem/Progenitor Cells. PLoS Genet 12(5):e1006055. PubMed: 27203244 MGI: J:231881
Zhang G; Xie Y; Zhou Y; Xiang C; Chen L; Zhang C; Hou X; Chen J; Zong H; Liu G. 2017. p53 pathway is involved in cell competition during mouse embryogenesis. Proc Natl Acad Sci U S A 114(3):498-503. PubMed: 28049824 MGI: J:239540
Zhang H; Liu L; Li X; Busayavalasa K; Shen Y; Hovatta O; Gustafsson JA; Liu K. 2014. Life-long in vivo cell-lineage tracing shows that no oogenesis originates from putative germline stem cells in adult mice. Proc Natl Acad Sci U S A 111(50):17983-8. PubMed: 25453063 MGI: J:218250
Zhang L; Zhang B; Han SJ; Shore AN; Rosen JM; Demayo FJ; Xin L. 2012. Targeting CreER(T2) expression to keratin 8-expressing murine simple epithelia using bacterial artificial chromosome transgenesis. Transgenic Res :. PubMed: 22350718 MGI: J:181829
Zhang M; Mani SB; He Y; Hall AM; Xu L; Li Y; Zurakowski D; Jay GD; Warman ML. 2016. Induced superficial chondrocyte death reduces catabolic cartilage damage in murine posttraumatic osteoarthritis. J Clin Invest 126(8):2893-902. PubMed: 27427985 MGI: J:237120
Zhang T; Liu J; Zhang J; Thekkethottiyil EB; Macatee TL; Ismat FA; Wang F; Stoller JZ. 2013. Jun is required in Isl1-expressing progenitor cells for cardiovascular development. PLoS One 8(2):e57032. PubMed: 23437302 MGI: J:199412
Zhang W; Menke DB; Jiang M; Chen H; Warburton D; Turcatel G; Lu CH; Xu W; Luo Y; Shi W. 2013. Spatial-temporal targeting of lung-specific mesenchyme by a Tbx4 enhancer. BMC Biol 11:111. PubMed: 24225400 MGI: J:225177
Zhang X; Garbett K; Veeraraghavalu K; Wilburn B; Gilmore R; Mirnics K; Sisodia SS. 2012. A Role for Presenilins in Autophagy Revisited: Normal Acidification of Lysosomes in Cells Lacking PSEN1 and PSEN2. J Neurosci 32(25):8633-48. PubMed: 22723704 MGI: J:185660
Zhang Y; Call MK; Yeh LK; Liu H; Kochel T; Wang IJ; Chu PH; Taketo MM; Jester JV; Kao WW; Liu CY. 2010. Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea. J Cell Sci 123(Pt 8):1285-94. PubMed: 20332116 MGI: J:159631
Zhang Y; Lam O; Nguyen MT; Ng G; Pear WS; Ai W; Wang IJ; Kao WW; Liu CY. 2013. Mastermind-like transcriptional co-activator-mediated Notch signaling is indispensable for maintaining conjunctival epithelial identity. Development 140(3):594-605. PubMed: 23293291 MGI: J:194073
Zhao C; Cai S; Shin K; Lim A; Kalisky T; Lu WJ; Clarke MF; Beachy PA. 2017. Stromal Gli2 activity coordinates a niche signaling program for mammary epithelial stem cells. Science 356(6335):. PubMed: 28280246 MGI: J:242165
Zhao C; Guo H; Li J; Myint T; Pittman W; Yang L; Zhong W; Schwartz RJ; Schwarz JJ; Singer HA; Tallquist MD; Wu M. 2014. Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation. Development 141(2):281-95. PubMed: 24335256 MGI: J:206589
Zhao W; Ajima R; Ninomiya Y; Saga Y. 2015. Segmental border is defined by Ripply2-mediated Tbx6 repression independent of Mesp2. Dev Biol 400(1):105-17. PubMed: 25641698 MGI: J:221162
Zhao Z; Zhu X; Cui K; Mancuso J; Federley R; Fischer K; Teng GJ; Mittal V; Gao D; Zhao H; Wong ST. 2016. In Vivo Visualization and Characterization of Epithelial-Mesenchymal Transition in Breast Tumors. Cancer Res 76(8):2094-104. PubMed: 26893478 MGI: J:231694
Zheng D; Limmon GV; Yin L; Leung NH; Yu H; Chow VT; Chen J. 2012. Regeneration of alveolar type I and II cells from Scgb1a1-expressing cells following severe pulmonary damage induced by bleomycin and influenza. PLoS One 7(10):e48451. PubMed: 23119022 MGI: J:192278
Zheng D; Yin L; Chen J. 2014. Evidence for Scgb1a1(+) cells in the generation of p63(+) cells in the damaged lung parenchyma. Am J Respir Cell Mol Biol 50(3):595-604. PubMed: 24134540 MGI: J:232094
Zheng W; Zhang H; Gorre N; Risal S; Shen Y; Liu K. 2014. Two classes of ovarian primordial follicles exhibit distinct developmental dynamics and physiological functions. Hum Mol Genet 23(4):920-8. PubMed: 24087793 MGI: J:206011
Zhong Z; Baker JJ; Zylstra-Diegel CR; Williams BO. 2012. Lrp5 and Lrp6 play compensatory roles in mouse intestinal development. J Cell Biochem 113(1):31-8. PubMed: 21866564 MGI: J:179033
Zhong Z; Zylstra-Diegel CR; Schumacher CA; Baker JJ; Carpenter AC; Rao S; Yao W; Guan M; Helms JA; Lane NE; Lang RA; Williams BO. 2012. Wntless functions in mature osteoblasts to regulate bone mass. Proc Natl Acad Sci U S A 109(33):E2197-204. PubMed: 22745162 MGI: J:188416
Zhong ZA; Zahatnansky J; Snider J; Van Wieren E; Diegel CR; Williams BO. 2015. Wntless spatially regulates bone development through beta-catenin-dependent and independent mechanisms. Dev Dyn 244(10):1347-55. PubMed: 26249818 MGI: J:226188
Zhou B; Pu WT. 2012. Genetic Cre-loxP assessment of epicardial cell fate using Wt1-driven Cre alleles. Circ Res 111(11):e276-80. PubMed: 23139287 MGI: J:205034
Zhou HJ; Qin L; Zhang H; Tang W; Ji W; He Y; Liang X; Wang Z; Yuan Q; Vortmeyer A; Toomre D; Fuh G; Yan M; Kluger MS; Wu D; Min W. 2016. Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med 22(9):1033-42. PubMed: 27548575 MGI: J:240446
Zhu X; Hill RA; Dietrich D; Komitova M; Suzuki R; Nishiyama A. 2011. Age-dependent fate and lineage restriction of single NG2 cells. Development 138(4):745-53. PubMed: 21266410 MGI: J:167902
Zhu Y; He Q; Aydin C; Rubera I; Tauc M; Chen M; Weinstein LS; Marshansky V; Juppner H; Bastepe M. 2016. Ablation of the Stimulatory G Protein alpha-Subunit in Renal Proximal Tubules Leads to Parathyroid Hormone-Resistance With Increased Renal Cyp24a1 mRNA Abundance and Reduced Serum 1,25-Dihydroxyvitamin D. Endocrinology 157(2):497-507. PubMed: 26671181 MGI: J:233851
Zhu Y; Zhang L; Gidday JM. 2013. Role of hypoxia-inducible factor-1alpha in preconditioning-induced protection of retinal ganglion cells in glaucoma. Mol Vis 19:2360-72. PubMed: 24319330 MGI: J:211869
Zito G; Saotome I; Liu Z; Ferro EG; Sun TY; Nguyen DX; Bilguvar K; Ko CJ; Greco V. 2014. Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk. Nat Commun 5:3543. PubMed: 24667544 MGI: J:210472
de Visser KE; Ciampricotti M; Michalak EM; Tan DW; Speksnijder EN; Hau CS; Clevers H; Barker N; Jonkers J. 2012. Developmental stage-specific contribution of LGR5(+) cells to basal and luminal epithelial lineages in the postnatal mammary gland. J Pathol 228(3):300-9. PubMed: 22926799 MGI: J:190035
van Amerongen R; Bowman AN; Nusse R. 2012. Developmental Stage and Time Dictate the Fate of Wnt/beta-Catenin-Responsive Stem Cells in the Mammary Gland. Cell Stem Cell 11(3):387-400. PubMed: 22863533 MGI: J:186834
van Berlo JH; Kanisicak O; Maillet M; Vagnozzi RJ; Karch J; Lin SC; Middleton RC; Marban E; Molkentin JD. 2014. c-kit+ cells minimally contribute cardiomyocytes to the heart. Nature 509(7500):337-41. PubMed: 24805242 MGI: J:210584
van de Pavert SA; Ferreira M; Domingues RG; Ribeiro H; Molenaar R; Moreira-Santos L; Almeida FF; Ibiza S; Barbosa I; Goverse G; Labao-Almeida C; Godinho-Silva C; Konijn T; Schooneman D; O'Toole T; Mizee MR; Habani Y; Haak E; Santori FR; Littman DR; Schulte-Merker S; Dzierzak E; Simas JP; Mebius RE; Veiga-Fernandes H. 2014. Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity. Nature 508(7494):123-7. PubMed: 24670648 MGI: J:208884
von Gise A; Zhou B; Honor LB; Ma Q; Petryk A; Pu WT. 2011. WT1 regulates epicardial epithelial to mesenchymal transition through beta-catenin and retinoic acid signaling pathways. Dev Biol 356(2):421-31. PubMed: 21663736 MGI: J:175466

Also Known As: mT/mG

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Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo

Allele Symbol: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo

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This mouse can be used to support research in many areas including:

Genotype: GFP related

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Genotype: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luoinvolves: 129S1/Sv * 129X1/SvJ

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Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}

Allele Symbol: Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}

Genotype: Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}/Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}
involves: 129S1/Sv * 129X1/SvJ

Additional - Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo} related