Through high density SNP analysis, some AXB and BXA recombinant inbred strains were shown to be the same or nearly the same genetically.  BXA17/Pgn was found to be a replica of BXA8/Pgn.  BXA17/Pgn was lost in 1989 or 1990.<br>The AXB and BXA set of RI strains are useful in the genetic analysis of several complex diseases including cardiovascular disease, diabetes, cancer, cleft palate, and hydrocephalus. The individual strains within the RI set also differ in their susceptibility to infectious diseases and in their responses to alcohol, stress, and endotoxin. <p>The strain distribution pattern (SDP) for the BXA RI strains is available through the Mouse Genome Informatics 

<a href=" http://www.informatics.jax.org/downloads/datasets/index.html#MGIRI"target="_blank"> Contributed Data Sets</a> and <a href=" http://gn2.genenetwork.org/"target="_blank"> Gene Network</a>.


Additional tools and information are presented through the Mouse Phenome Database 

<a href=" http://phenome.jax.org/panels/AXB_BXA"target="_blank"> Specialized Strain Panel Query Form</a>, and 

<a href=" http://www.genenetwork.org/mouseCross.html"target="_blank"> Gene Network </a>.



The AXB and BXA set of RI strains are useful in the genetic analysis of complex diseases. The individual strains within the RI set also differ in their susceptibility to infectious diseases and in their responses to alcohol, stress, and endotoxin. AXB and BXA strains are derived from the C57BL/6J (Stock No. 000664) and A/J (Stock No. 000646) progenitor strains.

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