These transgenic mice express Cre recombinase under the control of the mouse S100a4, S100 calcium binding protein A4, promoter. Cre recombinase expression is detected specifically in stromal fibroblasts of tissues such as the prostate, forestomach, mammary gland. Mice that are homozygous for the transgene are viable, normal in size and do not display any gross physical or behavioral abnormalities. 

Of note, this transgene is also available on a congenic BALB/c genetic background as Stock No. <a href="https://www.jax.org/strain/012641">012641</a>.

In an attempt to offer alleles on well-characterized or multiple genetic backgrounds, alleles are frequently moved to a genetic background different from that on which an allele was first characterized. It should be noted that the phenotype of these B6-congenic mice could vary from that originally described on a BALB/c genetic background. We may modify the strain description if necessary as published results become available.

Use of MICE by companies or for-profit entities requires a license prior to shipping.

 This transgenic cre strain (also called FSP1cre) may be useful for generating fibroblast specific-targeted mutants.

A minimum of two mice must be ordered. Additional mice will be charged on a per-mouse basis. Click the “Details” button to learn more.

Our minimum guarantee for cryorecovery orders is 2 carriers. To ensure that your colony can be rapidly expanded upon arrival, additional carriers may be added to your order.