FVB-Tg(Myh6/tetO-Bex1)12.2Jmol/J

Stock number: 030368
Product name: Bex1 Tg
Research areas: Research Tools

Description

These animals conditionally over-express full-length mouse Bex1 (brain expressed X-linked 1) cDNA from the cardiac-specific Myh6/tetO promoter. When bred with transgenic mice expressing a tetracycline transactivator or reverse transactivator protein, cardiac-specific expression can be controlled by withdrawal or administration of a tetracycline analog.

Detailed description

These animals conditionally over-express full-length mouse Bex1 (brain expressed X-linked 1) cDNA from the cardiac-specific Myh6/tetO promoter. Mice exhibit no overt phenotype at baseline. When bred with transgenic mice expressing a tetracycline transactivator or reverse transactivator protein, cardiac-specific expression can be controlled by withdrawal or administration of a tetracycline analog.

Development

Full-length mouse Bex1 cDNA was placed under the regulatory control of the mouse Myh6 promoter/tetO. The mutation was created and maintained on an FVB genetic background by the donating laboratory.