The Quackenbush Swiss inbred line 5 (QSi5) mice were selectively bred for high number of pups born alive (NBA) and low interlitter interval (ILI) over 50+ generations. QSi5 mice has an NBA of 13.4 and an ILI of 29 days, averaged over the first four parities, and a total productivity of 50.7 NBA. Females exhibit high milk production. This strain has been used for multiple quantitative trait loci (QTL) studies including, but not limited to, steady state platelet count (with CBA/CaH), maternal performance, lactational performance, and cardiac atrial septal morphology (with 129T2). The excellent reproductive performance of this strain makes it useful for resource creation including analysis of QTL, advanced intercross lines, and cost-effective congenic lines.Information on QSi5 is available at <a href="https://phenome.jax.org/strains/781"> The Mouse Phenome Database </a>. Haplotype data is available at <a href="https://data.broadinstitute.org/mouse/hapmap/prev_index.html"> The Broad Institute</a>.

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QSi5 inbred mice were selectively bred for increased litter size and 
decreased time between litters. The excellent reproductive performance 
of this strain makes it useful for resource creation including analysis 
of quantitative trait loci, advanced intercross lines, and 
cost-effective congenic lines.

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