The BXD recombinant inbred (RI) strains are used to study the genetics of behavioral phenotypes including alcohol and drug addiction, stress, and locomotor activity. The BXD set of RI strains also are used in the genetic analysis of numerous complex or potentially complex physiologic phenotypes including differences in organ weight and bone mineral density. This set is useful in QTL mapping and analysis of gene function. The strain distribution pattern (SDP) for the BXD RI strains is available through the Mouse Genome Informatics <a href=" http://www.informatics.jax.org/downloads/datasets/index.html#MGIRI" target="_blank"> Contributed Data Sets</a> and <a href=" http://gn2.genenetwork.org/" target="_blank"> Gene Network</a>. Additional tools and information are presented through the Mouse Phenome Database <a href=" http://phenome.jax.org/panels/BXD" target="_blank"> Specialized Strain Panel Query Form</a>, and <a href=" http://www.genenetwork.org/mouseCross.html" target="_blank"> Gene Network </a>. Of note, the small eye phenotype is segregating in this colony.

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The BXD#/Rww recombinant inbred (RI) strains originate from crosses between C57BL/6J (<a href="https://www.jax.org/strain/000664">000664</a>) females and DBA/2J (<a href="https://www.jax.org/strain/000671">000671</a>) males. They may be used to study the genetics of behavioral phenotypes (including alcohol and drug addiction, stress, and locomotor activity) and complex or potentially complex physiologic phenotypes (including differences in organ weight and bone mineral density).

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