Females heterozygous for the Tabl mutation have a striped pattern in their fur and hemizygous males have sparse fur, similar to the phenotype found for Eda mutants and this spontaneous mutation maps to a region of the X Chromosome that includes Eda. Heterozygous females can breed and when crossed to wild type males they produce both affected and unaffected males and females. Generally hemizygous males can also breed but not all are productive breeders and histology found aspermia in two hemizygous males at four weeks of age with abnormal seminiferous tubules in one of those.

Females heterozygous for the Tabl mutation have a striped pattern in their fur and hemizygous males have sparse fur, similar to the phenotype found for Eda mutants and this spontaneous mutation maps to a region of the X Chromosome that includes Eda.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

Typically mice are recovered in 12-16 weeks. <a target="_blank" href="https://www.jax.org/jax-mice-and-services/customer-support" rel="noreferrer">Contact Customer Service</a> to place an order or for more information.