Mice homozygous for the flimsy hind leg mutation drag one or both hind feet or legs when walking. There is variable expressivity such that some homozygotes clearly display the phenotype at wean age while other have a more mild phenotype with a slightly later presentation. In some homozygotes one hind leg is more severely impacted than the other or is faster to present the phenotype. This spontaneous mutation has been mapped to Chromosome 2 with no recombinants of 12 mutants assessed for rs3682381 and no recombinants of 10 mutants assessed for rs4223212.

This spontaneous mutation causes homozygotes to drag one of both hind feet or legs when walking

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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