CByJ;B6ByJ-skp/GrsrJ

Stock number: 022008
Research areas: Developmental Biology Research, Neurobiology Research, Reproductive Biology Research, Sensorineural Research

Description

Skimpy homozygotes are smaller than their littermates, walk on their toes, have poor balance, and die by four weeks of age.

Detailed description

Skimpy homozygotes are smaller than their littermates, walk on their toes, have poor balance, and die by four weeks of age.

Development

The skimpy mutation arose spontaneously in the strain CXB5/ByJ at The Jackson Laboratory in 2001 when that recombinant inbred strain was at generation F107. This mutant subline was maintained by sibling inbreeding progeny tested heterozygotes and in 2014 sperm was cryopreserved from heterozygous males. Cryo-recovery will use BALB/cByJ oocytes.

Allele

Symbol: skp
Name: skimpy
MGI accession ID: MGI:4365786
Generation method: Spontaneous
Marker symbol: skp
Marker name: skimpy
Chromosome: 7
Strain of origin: Not Specified
Molecular note: This spontaneous mutation was identified at The Jackson Laboratory.