Mice homozygous for the fused phalanges 4 Jackson mutation have fused or missing third digits of the hind feet.
The fused phalanges 4 Jackson mutation arose spontaneously in the BALB/cByJ-Map7mshi/J strain at The Jackson Laboratory and the Map7mshi mutation was selectively bred out. In 2013 sperm was cryopreserved from Fbn2fp-4J homozygous males.
|Allele Name||fused phalanges 4 Jackson|
|Gene Symbol and Name||Fbn2, fibrillin 2|
|Strain of Origin||CByJ.CBy-Map7mshi/J|
|Molecular Note||This spontaneous A-to-G variant at Chr18: 58,035,907 (GRCm38) (T-to-C on negative gene strand) results in the missense mutation p.S2267P in one transcript of fibrillin 2 and p.S998P in a second transcript.|
When using the BALB/cByJ-Fbn2fp-4J/GrsrJ mouse strain in a publication, please cite the originating article(s) and include JAX stock #021490 in your Materials and Methods section.