These transgenic mice express two distinct fluorophores in subsets of cells in the brain: a HA tagged YFP under the control of Mobp for yellow fluorescing oligodendrocytes, and mCherry under the control of Snap25 for red fluorescing neurons. Transgene expression, for each transgenic construct, mimics endogenous gene expression patterns. Hemizygotes are viable and fertile. The Donating Investigator has not attempted to make the strain homozygous.

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This bitransgenic mouse model allows distinct fluorescent visualization of neurons and oligodendrocytes and may be useful for noninvasive and/or in vivo studies of the central nervous system and neural circuits, as well as a source for cell culture experiments.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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