This compound transgenic strain was created by co-injecting a BAC clone encoding the entire mouse Per1 locus and a transgenic vector in which the Per1 promoter drives expression of luciferase (Per1:luc). The expression of Per1:luc oscillates in the suprachiasmatic nuclei (SCN) as well as peripheral tissues in ex vivo cultures (unlike most other Per1:luc transgenic strains which have weak rhythms in peripheral tissues).

This compound transgenic strain was created by co-injecting a BAC clone encoding the entire mouse Per1 locus and a transgenic vector in which the Per1 promoter drives expression of luciferase (Per1:luc). Unlike most Per1:luc transgenic mice, expression of Per1:luc oscillates in the suprachiasmatic nuclei (SCN) as well as peripheral tissues in ex vivo cultures. This strain may be useful in studies of circadian rhythm.

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