The loop tail like mutation is similar to the loop tail mutation of the <i>Vangl2</i> gene  in causing neurodevelopmental defects leading to short, curly tails and spina bifida.  There is incomplete penetrance and prenatal and perinatal lethality.  Some heterozygous with mild spina bifida survive to adulthood and have bred.  Some heterozygous females have closed vaginas. 

Mutant mice exhibit neurodevelopmental defects leading to short, curly tails and spina bifida.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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