Mice hemizygous for the ePet-Cre transgene are viable and fertile, with the FEV (ePet or Pet1 ETS oncogene family) promoter sequence directing expression of Cre recombinase in all mid-hindbrain serotonin (5HT)-synthesizing neurons and their postmitotic precursors.  When these transgenic mice are bred with mice containing a <i>loxP</i>-flanked sequence, Cre-mediated recombination is expected to result in deletion of the floxed sequences in the Cre recombinase-expressing tissues of the offspring.  These mice may be useful for inducing cre-mediated recombination in serotonergic neurons. 

These mice express cre under the direction of the <i>Fev</i> promoter. They may be useful for inducing cre-mediated recombination in serotonergic neurons. 



Live mice available in varying quantities. Check with customer service for specifics.