This congenic expresses the C57BL/6J derived sequence of Fscn2, rather than the Fscn2ahl8 sequence, and has a resulting amelioration of the early onset hearing loss characteristic in DBA/2J mice. Distinct from the DBA/2J host background these congenic mice have click, 8 kHz, and 16 kHz ABR thresholds at 2 months of age that are equivalent to those of C57BL/6J, although the 32 kHz thresholds are elevated similar to those of DBA/2J. This congenic rescue is similar to that found in the transgenic rescue in DBA/2J-Tg(RP24-180N9)2Kjn/Kjn (stock #012440).

This congenic expresses the C57BL/6J derived sequence of Fscn2, rather than the Fscn2ahl8 sequence, and has a resulting amelioration of the early onset hearing loss characteristic in DBA/2J mice. This congenic rescue is similar to that found in the transgenic rescue in DBA/2J-Tg(RP24-180N9)2Kjn/Kjn (stock #012440).

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

Typically mice are recovered in 12-16 weeks. <a target="_blank" href="https://www.jax.org/jax-mice-and-services/customer-support" rel="noreferrer">Contact Customer Service</a> to place an order or for more information.