This Myc-tagged <i>Piwil4</i> (piwi-like homolog 4 (Drosophila); also known as Miwi2) transgenic line permits the biochemical purification of the Miwi2 complex (a key component of the piRNA pathway) using robust anti-Myc antibodies. Expression, under the control of the transgene's native promoter, reproduces the developmentally timed pattern and subcellular localization of the endogenous protein. It begins as early as embryonic day 14.5 (E14.5) in developing germ cells of the testes and persists until shortly after birth. This strain may be helpful in studies of stem cell differentiation and spermatogenesis.

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This Myc-tagged <i>Piwil4</i> (piwi-like homolog 4 (Drosophila); also known as Miwi2) transgenic line permits the biochemical purification of the Miwi2 complex (a key component of the piRNA pathway)  using robust anti-Myc antibodies. This strain may be helpful in studies of stem cell differentiation and spermatogenesis.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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