This is one of two reciprocal congenic strains generated to characterize the <i>Cdh23</i> variant between CBA/CaJ and C57BL/6J.  This strain has the wild-type allele of cadherin 23 from CBA/CaJ on the C57BL/6J background, resulting in a predominantly C57BL/6J mouse in which age related hearing loss is delayed and less severe compared with normal C57BL/6J mice. Photomicrographs of cochlear surface preparations show that despite no longer carrying the age related hearing loss mutation, this predominantly C57BL/6J strain does have some inner hair cells missing at 18 months of age.

This congenic is valuable in the study of the genetically complex phenotype of age related hearing loss.

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