Mice hemizygous for the mouse <i>Lactb</i> (lactamase, beta)  transgene are viable, fertile, normal in size and do not display any gross behavioral abnormalities. The transgene encompasses the entire mouse structural gene and its regulatory sequences.  Transgenic mice have a higher fat-mass-to-lean-mass (FMLM) ratio compared to wild-type littermates when fed a 6% fat diet. Over time the FMLM ratio difference between transgenic and wild-type animals increases. This mutant mouse strain may be useful in studies of metabolic syndrome and obesity.

Mice hemizygous for the mouse <i>Lactb</i> (lactamase, beta) transgene have a higher fat-mass-to-lean-mass (FMLM) ratio compared to wild-type littermates when fed a 6% fat diet. Over time the FMLM ratio difference between transgenic and wild-type animals increases. This mutant mouse strain may be useful in studies of metabolic syndrome and obesity.


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