Mouse Strain Datasheet - 008715
Mouse Strain Datasheet - 008715
Mice carrying this targeted mutation of Ywhae (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide) exhibit hippocampal defects, neuronal migration abnormalities, and increased apoptosis in the brain. This mutant mouse strain may be useful in studies of Miller-Dieker Lissencephaly Syndrome and neuronal migration during brain development.
Dr. Anthony Wynshaw-Boris, Case Western Reserve University, School of Medicine
| Genetic Background | Generation |
|---|---|
|
|
| Allele Type | Gene Symbol | Gene Name |
|---|---|---|
| Targeted (Null/Knockout) | Ywhae | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide |
| Service | Genotype | Price |
|---|---|---|
| Heterozygous or wildtype for whae<tm1Awb> |
We will fulfill your order by providing at least two carriers for each strain ordered. The total number, sex, and genotypes provided will vary, although typically 8 or more animals are provided. Please check genotypes which will be recovered. While the genotypes of all animals produced will be communicated to you prior to scheduling shipment, the genotypes of animals provided may not reflect the mating scheme and genotypes described in the strain description. Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, then delivery time would increase to approximately 25 weeks. If we fail to produce animals of the correct genotype, you will not be charged. We cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.
Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation.
| Frozen Mouse Embryo | 129S-Ywhae<tm1Awb>/J Frozen Embryo | $2595.00 |
| Frozen Mouse Embryo | 129S-Ywhae<tm1Awb>/J Frozen Embryo | $2595.00 |
| Frozen Mouse Embryo | 129S-Ywhae<tm1Awb>/J Frozen Embryo | $3373.50 |
| Frozen Mouse Embryo | 129S-Ywhae<tm1Awb>/J Frozen Embryo | $3373.50 |
