Mouse Strain Datasheet - 008577
Mouse Strain Datasheet - 008577
Homozygous targeted mutant mice have thymocytes and splenocytes that, studied in vitro, are insensitive to pH-dependent cAMP production. A preliminary examination of homozygous animals has not revealed any major abnormalities in the development of the immune system or in its major functions. A green fluorescent protein (GFP) insertion acts as a marker for cells that normally express the targeted gene. This strain may be helpful in elucidating the role of this and other G protein-coupled receptors in the regulation of immune cell responses in acidic microenvironments.
Owen Witte, University of California, Los Angeles
| Genetic Background | Generation |
|---|---|
|
|
| Allele Type | Gene Symbol | Gene Name |
|---|---|---|
| Targeted (Reporter, Null/Knockout) | Gpr65 | G-protein coupled receptor 65 |
| Service | Genotype | Price |
|---|---|---|
| Heterozygous or wildtype for Gpr65<tm1Witt> |
We will fulfill your order by providing at least two carriers for each strain ordered. The total number, sex, and genotypes provided will vary, although typically 8 or more animals are provided. Please check genotypes which will be recovered. While the genotypes of all animals produced will be communicated to you prior to scheduling shipment, the genotypes of animals provided may not reflect the mating scheme and genotypes described in the strain description. Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, then delivery time would increase to approximately 25 weeks. If we fail to produce animals of the correct genotype, you will not be charged. We cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.
Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation.
| Frozen Mouse Embryo | B6.129X1-Gpr65<tm1Witt>/J Frozen Embryo | $2595.00 |
| Frozen Mouse Embryo | B6.129X1-Gpr65<tm1Witt>/J Frozen Embryo | $2595.00 |
| Frozen Mouse Embryo | B6.129X1-Gpr65<tm1Witt>/J Frozen Embryo | $3373.50 |
| Frozen Mouse Embryo | B6.129X1-Gpr65<tm1Witt>/J Frozen Embryo | $3373.50 |
