Overview

This strain is extinct. Please search JAX^® Mice Database for other alleles of Myo6.

Genetic overview

Genetic Background	Generation

Myo6^sv-4J

Allele Type	Gene Symbol	Gene Name
Spontaneous	Myo6	myosin VI

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Research Applications

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Details

Control Suggestions

Heterozygote from the colony
002448 129S1/SvImJ

Additional Information

Considerations for Choosing Controls

Selected References

Kane K; Johnson KR. 2008. Snell's waltzer 4J, a new spontaneous mutation in the Myo6 gene MGI Direct Data SubmissionMGI: J:135836

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Genetics

Myo6^sv-4J

Allele Symbol: Myo6^sv-4J

Allele Name	Snell's waltzer 4 Jackson
Allele Type	Spontaneous
Allele Synonym(s)
Gene Symbol and Name	Myo6, myosin VI
Gene Synonym(s)
Strain of Origin	129S1/SvImJ
Chromosome	9
Molecular Note	Non-complementation with the sv-2J allele proved this spontaneous mutation allelic.

Disease/Phenotype

Disease Terms

Research Areas By Phenotype

This mouse can be used to support research in many areas including:

Mammalian Phenotype Terms by Genotype

The following phenotype relates to a compound genotype created using this strain

Genotype: Myo6^sv-4J/Myo6^sv-4J
129S1/SvImJ-Myo6/J

behavior/neurological phenotype

circling

head shaking

head tossing

hearing/vestibular/ear phenotype

deafness

increased or absent threshold for auditory brainstem response
- at 6 to 7 weeks of age 100 dB SPL evoked no response

References

Kane K; Johnson KR. 2008. Snell's waltzer 4J, a new spontaneous mutation in the Myo6 gene MGI Direct Data SubmissionMGI: J:135836

Additional - Myo6^sv-4J related

Technical Support

CONTACT TECHNICAL SUPPORT

Genotyping Protocols
- Genotyping resources and troubleshooting

Terms Of Use

General Terms and Conditions

Questions about Terms of Use

Licensing Information

Phone: 207-288-6470

Email: TechTran@jax.org

Genetic overview

Research Applications

Control Suggestions

Additional Information

Selected References

Myo6sv-4J

Allele Symbol: Myo6sv-4J

Disease Terms

Research Areas By Phenotype

This mouse can be used to support research in many areas including:

Mammalian Phenotype Terms by Genotype

Genotype: Myo6sv-4J/Myo6sv-4J129S1/SvImJ-Myo6/J

behavior/neurological phenotype

hearing/vestibular/ear phenotype

References

Additional - Myo6sv-4J related

Genotyping Protocols

Terms Of Use

Licensing Information

Myo6^sv-4J

Allele Symbol: Myo6^sv-4J

Genotype: Myo6^sv-4J/Myo6^sv-4J
129S1/SvImJ-Myo6/J

Additional - Myo6^sv-4J related