Mice that carry this transgene are viable, fertile and do not display any gross physical or behavioral abnormalities.  Mice transgenic for this "GC-B1" isoform do not have a remarkable phenotype, but when bred to mice carrying a targeted knockout of the gene, this transgene rescues their severe dwarfism and early death phenotypes.  These mice may be used in studies of endochondral ossification and bone development.

These mice, transgenic for this ?GC-B1? isoform of the gene, do not have a remarkable phenotype. But when bred to mice carrying a targeted knockout of the gene, this transgene rescues their severe dwarfism and early death phenotypes. These mice may be used in studies of endochondral ossification and bone development.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

Typically mice are recovered in 12-16 weeks. <a target="_blank" href="https://www.jax.org/jax-mice-and-services/customer-support" rel="noreferrer">Contact Customer Service</a> to place an order or for more information.