Mice that carry this transgene are viable, fertile and significantly smaller than wildtype mice.  At 10 days of age, expression of the transgenic &#8220;GC-B2&#8221; isoform is found in growth plate cartilage and cGMP levels of tail bones are decreased by 25%.  Skeletal growth, as measured by naso-anal length, is slightly reduced as compared with wildtype mice. These mice may be used in studies of endochondral ossification and bone development.

Mice that carry this transgene are significantly smaller than wildtype mice.  At 10 days of age, expression of the transgenic &#8220;GC-B2&#8221; isoform is found in growth plate cartilage and cGMP levels of tail bones are decreased by 25%.  These mice may be used in studies of endochondral ossification and bone development.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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