Mice that carry this transgene are viable, fertile and significantly smaller than wildtype mice.  At 10 days of age, expression of the transgenic &#8220;GC-B2&#8221; isoform is found in growth plate cartilage and cGMP levels of tail bones are decreased by 25%.  Skeletal growth, as measured by naso-anal length, is slightly reduced as compared with wildtype mice. These mice may be used in studies of endochondral ossification and bone development.

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Mice that carry this transgene are significantly smaller than wildtype mice.  At 10 days of age, expression of the transgenic &#8220;GC-B2&#8221; isoform is found in growth plate cartilage and cGMP levels of tail bones are decreased by 25%.  These mice may be used in studies of endochondral ossification and bone development.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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