Hemizygous mice are viable and fertile.  When young, these mice look similar to wildtype mice, but as they age, their coats become shorter and more sparse.  Molecular analysis shows delayed development of sebaceous glands, accelerated hair cycle and less-differentiated epidermis.  RNA and protein expressed from the transgene are detected in skin as determined by Western and Northern analysis.  This strain may be useful as a model for skin and hair development studies. 

-When young, these mice look similar to wildtype mice, but as they age, their coats become shorter and more sparse. Molecular analysis shows delayed development of sebaceous glands, accelerated hair cycle and less-differentiated epidermis. This strain may be useful as a model for skin and hair development studies.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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B6;SJL-Tg(KRT14-Hr)551Cct/J Frozen Embryo