IMR Colony, The Jackson Laboratory
|Allele Name||targeted mutation 1, Peter Mombaerts|
|Allele Type||Targeted (Null/Knockout)|
|Allele Synonym(s)||beta-; CBeta-; TCRb-; TCRbeta-; TCR-Cbeta-|
|Gene Symbol and Name||Tcrb, T cell receptor beta chain|
|Strain of Origin||129P2/OlaHsd|
|Molecular Note||15kb of sequence was replaced with a PGK-neo cassette. The deletion included one of the two D gene segments, ten of the twelve J gene segments, and both constant gene segments.|
|Mutations Made By|| |
Peter Mombaerts, Max Planck Research Unit for Neurogenetics
When maintaining a live colony, homozygous mice may be bred together.
When using the TCRbeta- mouse strain in a publication, please cite the originating article(s) and include JAX stock #007081 in your Materials and Methods section.