Mice homozygous for this floxed allele are viable and fertile. These mutant mice have loxP sites flanking the C-terminal coding exon. When bred to Cre-recombinase expressing mice, offspring will have a deletion of this exon in the cre expressing tissue(s). These floxed mice may be useful in studying steroidogenic factors and pituitary gonadotrope function.
 For example, when crossed to a strain expressing Cre recombinase in the anterior and intermediate lobes of the pituitary gland (see Stock No. <a href="https://www.jax.org/strain/004426">004426</a>), this mutant mouse strain may be useful in studies of pituitary gonadotrope function.

These floxed mutant mice possess loxP sites flanking the C-terminal coding exon of the Nr5a1 gene. This strain may be useful for generating conditional mutations in applications studying steroidogenic factors and pituitary gonadotrope function.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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