Peter Mombaerts, Max Planck Research Unit for Neurogenetics
Genetic Background | Generation |
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|
Allele Type | Gene Symbol | Gene Name |
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Targeted (Reporter, Null/Knockout) | Olfr160 | olfactory receptor 160 |
This targeted mutation was generated in 129P2/OlaHsd derived E14 ES cells and the resulting mice from clone W213 were crossed to Tg(EIIa-cre) bearing mice to excise the loxP flanked pgkneo (LNL) cassette. Although Tg(EIIa-cre) was generated in FVB/N mice, it was backcrossed onto C57BL/6J prior to this cross. The offspring were intercrossed and the transgene was selectively bred out of this line. Thus, this STOCK background is predominantly C57BL/6J and 129P2/OlaHsd. In 2007 sperm were cryopreserved from homozygous males.
Expressed Gene | GFP, Green Fluorescent Protein, |
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Expressed Gene | lacZ, beta-galactosidase, E. coli |
Site of Expression | GFP and lacZ are observed in olfactory sensory neurons located in the dorsal epithelium. |
Allele Name | targeted mutation 2, Peter Mombaerts |
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Allele Type | Targeted (Reporter, Null/Knockout) |
Allele Synonym(s) | GFP->M72-GFP-IRES-taulacZ; GFP->M72-LacZ(deltaM72); M72-IRES-tauGFP; Olfr160tm2(GFP)Mom |
Gene Symbol and Name | Olfr160, olfactory receptor 160 |
Gene Synonym(s) | |
Expressed Gene | GFP, Green Fluorescent Protein, |
Expressed Gene | lacZ, beta-galactosidase, E. coli |
Site of Expression | GFP and lacZ are observed in olfactory sensory neurons located in the dorsal epithelium. |
Strain of Origin | 129P2/OlaHsd |
Chromosome | 9 |
Molecular Note | The coding region was replaced with GFP and IRES-taulacZ. |
Mutations Made By | Peter Mombaerts, Max Planck Research Unit for Neurogenetics |
When using the ΔM72 mouse strain in a publication, please cite the originating article(s) and include JAX stock #006652 in your Materials and Methods section.
Facility Barrier Level Descriptions
Service/Product | Description | Price |
---|---|---|
Heterozygous for Olfr160<tm2(GFP)Mom> |
Frozen Mouse Embryo | STOCK Olfr160<tm2Mom>/MomJ | $2595.00 |
Frozen Mouse Embryo | STOCK Olfr160<tm2Mom>/MomJ | $2595.00 |
Frozen Mouse Embryo | STOCK Olfr160<tm2Mom>/MomJ | $3373.50 |
Frozen Mouse Embryo | STOCK Olfr160<tm2Mom>/MomJ | $3373.50 |
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