Brian Soper, The Jackson Laboratory
Genetic Background | Generation |
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|
Allele Type | Gene Symbol | Gene Name |
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Spontaneous | Gpi1 | glucose phosphate isomerase 1 |
The a-m1J mutation arose spontaneously on the CByJ.Cg-Foxn1nu/J background (Stock No. 000711) at the Jackson Laboratory in 2000. Heterozygous matings were used to breed away from the Foxn1nu mutation. This strain is segregating the Gpi1a and Gpi1a-m1J alleles. The colony was maintained in laboratory of Dr. Jane Barker and donated to the Repository in 2007.
Allele Name | mutant 1, Jackson |
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Allele Type | Spontaneous |
Allele Synonym(s) | Gpi1c-J |
Gene Symbol and Name | Gpi1, glucose phosphate isomerase 1 |
Gene Synonym(s) | |
Strain of Origin | CByJ.Cg-Foxn1nu/J |
Chromosome | 7 |
Molecular Note | In 2000, a mouse of BALB/cByJ background from a production colony at The Jackson Laboratory (TJL) was subjected to isoenzyme analysis in the TJL Quality Control Laboratory and found to have glucose phosphate isomerase 1 activity associated with an electrophoretic band of fast mobility identical to that of GPI1c, rather than the expected slower mobility of GPI1a. |
When using the CBy(Cg)-Gpi1a-m1J/BrkJ mouse strain in a publication, please cite the originating article(s) and include JAX stock #006560 in your Materials and Methods section.
Facility Barrier Level Descriptions
Service/Product | Description | Price |
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Heterozygous for Gpi1<a-m1J> |
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.
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