Brian Soper, The Jackson Laboratory
The a-m1J mutation arose spontaneously on the CByJ.Cg-Foxn1nu/J background (Stock No. 000711) at the Jackson Laboratory in 2000. Heterozygous matings were used to breed away from the Foxn1nu mutation. This strain is segregating the Gpi1a and Gpi1a-m1J alleles. The colony was maintained in laboratory of Dr. Jane Barker and donated to the Repository in 2007.
|Allele Name||mutant 1, Jackson|
|Gene Symbol and Name||Gpi1, glucose phosphate isomerase 1|
|Strain of Origin||CByJ.Cg-Foxn1nu/J|
|Molecular Note||In 2000, a mouse of BALB/cByJ background from a production colony at The Jackson Laboratory (TJL) was subjected to isoenzyme analysis in the TJL Quality Control Laboratory and found to have glucose phosphate isomerase 1 activity associated with an electrophoretic band of fast mobility identical to that of GPI1c, rather than the expected slower mobility of GPI1a.|
When using the CBy(Cg)-Gpi1a-m1J/BrkJ mouse strain in a publication, please cite the originating article(s) and include JAX stock #006560 in your Materials and Methods section.