CBy(Cg)-Gpi1^a-m1J/BrkJ

Stock number: 006560
Research areas: Research Tools

Development

The a-m1J mutation arose spontaneously on the CByJ.Cg-Foxn1^nu/J background (Stock No. 000711) at the Jackson Laboratory in 2000. Heterozygous matings were used to breed away from the Foxn1^nu mutation. This strain is segregating the Gpi1^a and Gpi1^a-m1J alleles. The colony was maintained in laboratory of Dr. Jane Barker and donated to the Repository in 2007.

Allele

Symbol: Gpi1^a-m1J
Name: mutant 1, Jackson
MGI accession ID: MGI:3764995
Generation method: Spontaneous
Synonyms: Gpi1^c-J
Marker symbol: Gpi1
Marker name: glucose phosphate isomerase 1
Marker synonyms: AMF; autocrine motility factor; GNPI; Gpi-1; Gpi-1r; Gpi1-r; Gpi-1s; Gpi1-s; Gpi-1t; Gpi1-t; maturation factor; MF; neuroleukin; NK; NK/GPI; Nlk; Org; PGI; Phi; SA36; SA-36
Chromosome: 7
Strain of origin: CByJ.Cg-Foxn1^nu/J
Molecular note: In 2000, a mouse of BALB/cByJ background from a production colony at The Jackson Laboratory (TJL) was subjected to isoenzyme analysis in the TJL Quality Control Laboratory and found to have glucose phosphate isomerase 1 activity associated with an electrophoretic band of fast mobility identical to that of GPI1^c, rather than the expected slower mobility of GPI1^a.