B6.129P2-Atp8a1^tm1Dgen/J

Stock number: 006433
Product name: Atp8a1-

Description

LacZ expression in these Atp8a1 knock-out/reporter mice is detected particularly in the nervous system and lungs.

Detailed description

This targeted mutant was created and characterized by Deltagen, Inc. View phenotypic data developed by Deltagen.

Allele

Symbol: Atp8a1^tm1Dgen
Name: targeted mutation 1, Deltagen
MGI accession ID: MGI:3663343
Generation method: Targeted
Attributes: Reporter; Null/Knockout
Marker symbol: Atp8a1
Marker name: ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
Chromosome: 5
Strain of origin: 129P2/OlaHsd
Expressed genes: lacZ,beta-galactosidase,E. coli
Molecular note: A LacZ-neomycin cassette was inserted into the gene so that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts were detected in all tissues analysed. LacZ expression was detected in most tissues examined, particularly nervous system and lungs. No LacZ expression was detected in lymph nodes, aorta, liver, or pancreas.