Mice homozygous for the severe runting mutation can be identified by their unusually small body size by approximately 2 weeks of age. Many homozygotes die by wean age and slight tremors are often observed before death.
The mutation severe runting arose spontaneously in 1998 in the C3H/HeJ colony at The Jackson Laboratory and has been maintained on this inbred background.
|Allele Name||severe runting|
|Gene Symbol and Name||sevr, severe runting|
|Strain of Origin||C3H/HeJ|
|Molecular Note||This mutation arose in a colony of inbred C3H/HeJ mice in the Mouse Mutant Resource at The Jackson Laboratory in 1998.|