B6.D2-(D13Mit314-D13Mit35)/1LusJ

Stock number: 006061
Strain synonyms: B6.D2-Chr13D
Research areas: Research Tools

Description

This strain is one of a set of overlapping congenic strains called genome-tagged mice (GTM). Each member of the panel carries an average of a 23 cM segment (range 8 to 58 cM) from DBA/2J introgressed on to a C57BL/6J background. GTM are a valuable resource for mapping and confirmation of loci contributing to complex traits.

Detailed description

This C57BL/6J congenic carries the distal portion of chromosome 13 from DBA/2J. The Mit or SNP (rs) markers in the strain name define the congenic interval.

Marker-assisted breeding was used to construct a set of overlapping congenic strains called genome-tagged mice (GTM) that span the entire mouse genome. Each member of the panel carries an average of a 23 cM segment (range 8 to 58 cM) from DBA/2J introgressed on to a C57BL/6J background. The segments represent the distal (D), middle (M), and proximal (P) portions of all or most of a given chromosome. (Iakoubova OA, et. al., 2001) GTM are a valuable resource for mapping and confirmation of loci contributing to complex traits.

The Jackson Laboratory is working with Dr. Lusis' group to import and make available additional strains in the panel.

Allele

MGI accession ID: MGI:89762
Marker symbol: D13Mit35
Marker name: DNA segment, Chr 13, Massachusetts Institute of Technology 35
Chromosome: 13

Allele

MGI accession ID: MGI:105837
Marker symbol: D13Mit314
Marker name: DNA Segment, Chr 13 Massachusetts Institute of Technology 314
Chromosome: 13