This strain is one of a set of overlapping congenic strains called genome-tagged mice (GTM). Each member of the panel carries an average of a 23 cM segment (range 8 to 58 cM) from DBA/2J introgressed on to a C57BL/6J background. GTM are a valuable resource for mapping and confirmation of loci contributing to complex traits.
Read More +Genetic Background | Generation |
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Marker Symbol | Marker Name | |
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D13Mit35 | DNA segment, Chr 13, Massachusetts Institute of Technology 35 | |
D13Mit314 | DNA Segment, Chr 13 Massachusetts Institute of Technology 314 |
This C57BL/6J congenic carries the distal portion of chromosome 13 from DBA/2J. The Mit or SNP (rs) markers in the strain name define the congenic interval.
Marker-assisted breeding was used to construct a set of overlapping congenic strains called genome-tagged mice (GTM) that span the entire mouse genome. Each member of the panel carries an average of a 23 cM segment (range 8 to 58 cM) from DBA/2J introgressed on to a C57BL/6J background. The segments represent the distal (D), middle (M), and proximal (P) portions of all or most of a given chromosome. (Iakoubova OA, et. al., 2001) GTM are a valuable resource for mapping and confirmation of loci contributing to complex traits.
The Jackson Laboratory is working with Dr. Lusis' group to import and make available additional strains in the panel.
When using the B6.D2-(D13Mit314-D13Mit35)/1LusJ mouse strain in a publication, please cite the originating article(s) and include JAX stock #006061 in your Materials and Methods section.
Facility Barrier Level Descriptions
Service/Product | Description | Price |
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Homozygous, 1 pair minimum |
Frozen Mouse Embryo | B6.D2-(D13Mit314-D13Mit35)/1LusJ Frozen Embryos | $2595.00 |
Frozen Mouse Embryo | B6.D2-(D13Mit314-D13Mit35)/1LusJ Frozen Embryos | $2595.00 |
Frozen Mouse Embryo | B6.D2-(D13Mit314-D13Mit35)/1LusJ Frozen Embryos | $3373.50 |
Frozen Mouse Embryo | B6.D2-(D13Mit314-D13Mit35)/1LusJ Frozen Embryos | $3373.50 |
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.
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