AK.L-Lith1^C57L/J Lith2^C57L/J/989Pgn

Stock number: 005896
Strain synonyms: AKR-lith1 lith2/989Pgn
Research areas: Internal/Organ Research, Research Tools

Development

This double congenic was constructed from the congenic strains AK.L-Lith1^C57L/J and AK.L-Lith2^C57L/J. At the time of the intercross both congenics were N5. Both the Lith1 and Lith2 congenics retain the lithogenic diet-induced gallstone susceptibility phenotype from C57L/J on the gallstone resistant AKR/J background.

Allele

Symbol: Lith2^C57L/J
Name: C57L/J
MGI accession ID: MGI:2446826
Generation method: QTL
Marker symbol: Lith2
Marker name: lithogenic gene 2
Chromosome: 19
Strain of origin: C57L/J
Molecular note: This allele confers susceptibility to gallstone formation compared to AKR/J.

Allele

Symbol: Lith1^C57L/J
Name: C57L/J
MGI accession ID: MGI:2446828
Generation method: QTL
Marker symbol: Lith1
Marker name: lithogenic gene 1
Chromosome: 2
Strain of origin: C57L/J
Molecular note: This allele confers susceptibility to gallstone formation compared to AKR/J.