This C57BL/6J congenic carries the middle portion of chromosome 2 from CAST/Ei. The Mit or SNP (rs) markers in the strain name define the congenic interval. <p>Marker-assisted breeding was used to construct a set of overlapping congenic strains called genome-tagged mice (GTM) that span the entire mouse genome.  Each member of the panel carries an average of a 23 cM segment (range 8 to 58 cM) from CAST/Ei introgressed on to a C57BL/6J background.  The segments represent the distal (D), middle (M),  and proximal (P) portions of all or most of a given chromosome. (Iakoubova OA, et. al., 2001) GTM are a valuable resource for mapping and confirmation of loci contributing to complex traits.  <p>The Jackson Laboratory is working with Dr. Lusis' group to import and make available additional strains in the panel.

This one of a set of congenic strains carrying chrosomal segments as identified by SNP markers from CAST/Ei on a C57BL/6J background.  This strain carries a segment from the middle portion of Chromosome 2.

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B6.CAST-(rs4222996-rs13476494)/LusJ Frozen Embryos