Mice homozygous for the Snell's waltzer mutations are characterized by circling and head tossing behavior.
The Jackson Laboratory cannot guarantee that cryorecovery of strains from the discontinued NIH-funded Neuroscience Mutagenesis Facility (NMF) will be successful or that the anticipated phenotype or genotype will be obtained. The cryorecovery fee for this effort will not be refunded or prorated if the recovery is unsuccessful or is in any way unsatisfactory. Genotyping will be the responsibility of the Purchaser.
The C57BL/6J background strain is homozygous for the age related hearing loss mutation Cdh23ahl, which on this background causes progressive hearing loss with onset after 10 months of age.
|Allele Name||Snell's waltzer 3 Jackson|
|Allele Type||Chemically induced (ENU)|
|Gene Symbol and Name||Myo6, myosin VI|
|Strain of Origin||C57BL/6J|
|Molecular Note||A complementation test with the original Snell's waltzer mutation showed this to be allelic with it.|