B6.D2-(D12Mit269-D12Mit134)/LusJ

Stock number: 005186
Product name: B6.D2.12C
Research areas: Research Tools

Description

These congenic genome-tagged mice carry a Chromosome 12 segment between markers Mit269to Mit134from the DBA/2 strain.

Development

This congenic panel was initiated by a cross of B6D2F1/J (Stock #100006) females to C57BL/6J males. Male progeny at each generation were selected by marker assisted genome scan and were backcrossed to C57BL/6J females to produce the N3-N6 generations. All animals in the panel carry a C57BL/6J Y chromosome. Sibling pairs at the N6 generation were intercrossed to produce homozygotes. Iakoubova OA, et. al. provides a more detailed explanation of the chromosome intervals. Dr. Lusis donated the panel to The Jackson Laboratory in 2004.

Allele

MGI accession ID: MGI:105435
Marker symbol: D12Mit269
Marker name: DNA segment, Chr 12, Massachusetts Institute of Technology 269
Chromosome: 12

Allele

MGI accession ID: MGI:89381
Marker symbol: D12Mit134
Marker name: DNA segment, Chr 12, Massachusetts Institute of Technology 134
Chromosome: 12