Routine ophthalmoscopic examination revealed mutants with retinal spots or mottled retina. Histology performed on a single eye surgically removed from a mutant at 186 days of age, revealed severe photoreceptor degeneration. Male mutants do not breed well, and the colony is maintained through heterozygote matings.
<p>Histology performed on a single eye surgically removed from a mutant at 186 days of age, revealed severe photoreceptor degeneration.


These mice carry an ENU-induced mutation that is characterized by photoreceptor degeneration.

<p><i>The Jackson Laboratory cannot guarantee that cryorecovery of strains from the discontinued NIH-funded Neuroscience Mutagenesis Facility (NMF) will be successful or that the anticipated phenotype or genotype will be obtained. The cryorecovery fee for this effort will not be refunded or prorated if the recovery is unsuccessful or is in any way unsatisfactory. Genotyping will be the responsibility of the Purchaser.</i>

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