Routine ophthalmoscopic examination at 12 weeks of age identified a grainy appearance of the retina in NMF191 mutants; electroretinographic recordings were normal (n=7). Standard pathology work-up on two mutants (92 days of age) revealed no gross morphological abnormalities. 

The mutants breed well, and the colony is maintained through regular breeding.





These mice carry an ENU-induced mutation that is characterized by a grainy appearing retina.

<p><i>The Jackson Laboratory cannot guarantee that cryorecovery of strains from the discontinued NIH-funded Neuroscience Mutagenesis Facility (NMF) will be successful or that the anticipated phenotype or genotype will be obtained. The cryorecovery fee for this effort will not be refunded or prorated if the recovery is unsuccessful or is in any way unsatisfactory. Genotyping will be the responsibility of the Purchaser.</i>

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