The predominant phenotypes of mice homozygous for the small body small eyes mutation (<i>sbse</i>) are small ear pinnae, craniofacial deformities, and a reduced body size such that the body weight is approximately 30% less than normal at 4, 8, 12, and 16 weeks of age.  Homozygotes also display hearing loss and reduced litter size.  The craniofacial defects include smaller skull, nose, and jaw lengths with domed skull compared with controls.

Homozygous <i>sbse</i> mice exhibit craniofacial deformities, reduced body size, and hearing loss.

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